Detalhe da pesquisa
1.
Plasma and cerebrospinal fluid pharmacokinetics of vodobatinib, a neuroprotective c-Abl tyrosine kinase inhibitor for the treatment of Parkinson's disease.
Parkinsonism Relat Disord
; 108: 105281, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36717298
2.
Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissues.
Sci Rep
; 10(1): 22155, 2020 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33335114
3.
Considerations for drug development biomarker assays in the clinical laboratory.
Bioanalysis
; 15(10): 533-536, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37293797
4.
Real-time observation of protein aggregates in pharmaceutical formulations using liquid cell electron microscopy.
Lab Chip
; 17(2): 315-322, 2017 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27934977
5.
Development and Validation of Electrochemiluminescence Assays to Measure Free and Total sSLAMF7 in Human Serum in the Absence and Presence of Elotuzumab.
AAPS J
; 18(4): 989-99, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27116021
6.
Anti-PEG antibody bioanalysis: a clinical case study with PEG-IFN-λ-1a and PEG-IFN-α2a in naive patients.
Bioanalysis
; 7(9): 1093-106, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26039807
7.
Development and Fit-for-Purpose Validation of a Soluble Human Programmed Death-1 Protein Assay.
AAPS J
; 17(4): 976-87, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25924887
8.
An integrated multiplatform bioanalytical strategy for antibody-drug conjugates: a novel case study.
Bioanalysis
; 7(13): 1569-82, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26226308
9.
Optimization of Rolling-Circle Amplified Protein Microarrays for Multiplexed Protein Profiling.
J Biomed Biotechnol
; 2003(5): 299-307, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-14688416
10.
Conjugated critical reagent characterization for ligand-binding assays: using MALDI-TOF-MS as an orthogonal tool to assess assay performance.
Bioanalysis
; 6(7): 983-92, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24806906
11.
Measuring biotherapeutics with endogenous counterparts and pre-existing antibodies: an interferon case study.
Bioanalysis
; 6(8): 1113-22, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24830895
12.
Targeting an acid labile aspartyl-prolyl amide bond as a viable alternative to trypsin digestion to generate a surrogate peptide for LC-MS/MS analysis.
Bioanalysis
; 6(22): 2985-98, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25496253
13.
The FDA/critical path initiative/Duke-Margolis center for health policy public workshop on analytical validation of assays for biomarker qualification: an update on the White Paper.
Bioanalysis
; 10(12): 893-896, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29924636
14.
Biomarker assay validation.
Bioanalysis
; 10(12): 889-891, 2018 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29939799
15.
Roux-en-Y gastric bypass corrects hyperinsulinemia implications for the remission of type 2 diabetes.
J Clin Endocrinol Metab
; 96(8): 2525-31, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21593117
16.
Clinical evaluation of the Elecsys total prostate-specific antigen assay on the Elecsys 1010 and 2010 systems.
Clin Chem
; 48(6 Pt 1): 944-7, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12029015