Detalhe da pesquisa
1.
Generalizing the Concept of Specific Compound Formulation Additives towards Non-Fluorescent Drugs: A Solubilization Study on Potential Anti-Alzheimer-Active Small-Molecule Compounds.
Angew Chem Int Ed Engl
; 55(30): 8752-6, 2016 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27282127
2.
Inhibition of tau filament formation by conformational modulation.
J Am Chem Soc
; 135(7): 2853-62, 2013 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23360400
3.
Antimicrobial, antiproliferative, cytotoxic, and tau inhibitory activity of rubellins and caeruleoramularin produced by the phytopathogenic fungus Ramularia collo-cygni.
Planta Med
; 75(14): 1523-5, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19565437
4.
Development of tau aggregation inhibitors for Alzheimer's disease.
Angew Chem Int Ed Engl
; 48(10): 1740-52, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19189357
5.
Screening of a neuronal cell model of tau pathology for therapeutic compounds.
Neurobiol Aging
; 76: 24-34, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30640040
6.
Mechanistic basis of phenothiazine-driven inhibition of Tau aggregation.
Angew Chem Int Ed Engl
; 52(12): 3511-5, 2013 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23401175
7.
Structural Basis of Small Molecule Targetability of Monomeric Tau Protein.
ACS Chem Neurosci
; 9(12): 2997-3006, 2018 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29944336
8.
Inhibition of tau aggregation in cell models of tauopathy.
Curr Alzheimer Res
; 4(5): 544-6, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18220518
9.
Screening for inhibitors of tau protein aggregation into Alzheimer paired helical filaments: a ligand based approach results in successful scaffold hopping.
Curr Alzheimer Res
; 4(3): 315-23, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17627489
10.
Inhibition of Tau Protein Aggregation by Rhodanine-based Compounds Solubilized Via Specific Formulation Additives to Improve Bioavailability and Cell Viability.
Curr Alzheimer Res
; 14(7): 742-752, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28155596
11.
Gaining Insights into Specific Drug Formulation Additives for Solubilizing a Potential Anti-Alzheimer Disease Drug B4A1.
Macromol Biosci
; 17(10)2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28488401
12.
Time course of Tau toxicity and pharmacologic prevention in a cell model of Tauopathy.
Neurobiol Aging
; 57: 47-63, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28600952
13.
Selection and Characterization of Tau Binding á´ -Enantiomeric Peptides with Potential for Therapy of Alzheimer Disease.
PLoS One
; 11(12): e0167432, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28006031
14.
Screening for inhibitors of tau polymerization.
Curr Alzheimer Res
; 2(2): 219-26, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15974921
15.
Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau.
Acta Neuropathol Commun
; 3: 25, 2015 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25958115
16.
Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies.
Curr Alzheimer Res
; 12(9): 814-28, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26510979
17.
Progress and developments in tau aggregation inhibitors for Alzheimer disease.
J Med Chem
; 56(11): 4135-55, 2013 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23484434
18.
Rhodanine-based tau aggregation inhibitors in cell models of tauopathy.
Angew Chem Int Ed Engl
; 46(48): 9215-9, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17985339
19.
"Lest we forget you--methylene blue...".
Neurobiol Aging
; 32(12): 2325.e7-16, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21316815
20.
N'-benzylidene-benzohydrazides as novel and selective tau-PHF ligands.
J Alzheimers Dis
; 27(4): 835-43, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21891864