Detalhe da pesquisa
1.
Development and Evaluation of a Height-Based Tobramycin Initial Dosing Nomogram for the Treatment of Adult Cystic Fibrosis Pulmonary Exacerbations.
Ther Drug Monit
; 45(2): 259-264, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36730982
2.
Consideration of height-based tobramycin dosing regimens for the treatment of adult cystic fibrosis pulmonary exacerbations.
Br J Clin Pharmacol
; 88(5): 2246-2255, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34820875
3.
Remdesivir (VEKLURY) for Treating COVID-19: Guinea Pig Ex Vivo and In Vivo Cardiac Electrophysiological Effects.
J Cardiovasc Pharmacol
; 80(4): 616-622, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35881906
4.
SCN5A-C683R exhibits combined gain-of-function and loss-of-function properties related to adrenaline-triggered ventricular arrhythmia.
Exp Physiol
; 106(3): 683-699, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33480457
5.
The guinea-pig expresses functional CYP2C and P-glycoprotein: further validation of its usefulness in drug biotransformation/transport studies.
Biopharm Drug Dispos
; 36(3): 183-203, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25472529
6.
Decreased CYP3A expression and activity in guinea pig models of diet-induced metabolic syndrome: is fatty liver infiltration involved?
Drug Metab Dispos
; 41(5): 952-7, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23412133
7.
Homologation of the Alkyl Side Chain of Antimitotic Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonate Prodrugs Selectively Targeting CYP1A1-Expressing Breast Cancers Improves Their Stability in Rodent Liver Microsomes.
J Med Chem
; 66(4): 2477-2497, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36780426
8.
Iloperidone (Fanapt®), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration.
Pharmacol Res
; 66(1): 60-5, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22465688
9.
Metabolic syndrome potentiates the cardiac action potential-prolonging action of drugs: a possible 'anti-proarrhythmic' role for amlodipine.
Pharmacol Res
; 65(3): 320-7, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22154802
10.
Prolongation of cardiac ventricular repolarization under paliperidone: how and how much?
J Cardiovasc Pharmacol
; 57(6): 690-5, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21394035
11.
Fingolimod (Gilenya® ) in multiple sclerosis: bradycardia, atrioventricular blocks, and mild effect on the QTc interval. Something to do with the L-type calcium channel?
Fundam Clin Pharmacol
; 31(4): 392-402, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28299825
12.
Altered Protein Expression of Cardiac CYP2J and Hepatic CYP2C, CYP4A, and CYP4F in a Mouse Model of Type II Diabetes-A Link in the Onset and Development of Cardiovascular Disease?
Pharmaceutics
; 9(4)2017 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29023376
13.
A novel nonsense mutation in the SCN5A gene leads to Brugada syndrome and a silent gene mutation carrier state.
Can J Cardiol
; 21(11): 925-31, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16239976
14.
Modulation of CYP3a expression and activity in mice models of type 1 and type 2 diabetes.
Pharmacol Res Perspect
; 2(6): e00082, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25505621
15.
Tizanidine (Zanaflex): a muscle relaxant that may prolong the QT interval by blocking IKr.
J Cardiovasc Pharmacol Ther
; 17(1): 102-9, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21317414
16.
Galantamine (Reminyl) delays cardiac ventricular repolarization and prolongs the QT interval by blocking the HERG current.
Eur J Pharmacol
; 681(1-3): 68-74, 2012 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22366430
17.
QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile.
Fundam Clin Pharmacol
; 26(5): 599-608, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21623902
18.
A novel KCNQ1 variant (L203P) associated with torsades de pointes-related syncope in a Steinert syndrome patient.
Can J Cardiol
; 27(2): 263.e5-12, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21459285
19.
Toward optimal treatment in women: the effect of sex on metoprolol-diphenhydramine interaction.
J Clin Pharmacol
; 50(2): 214-25, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19948945
20.
Influence of the menstrual cycle on the timing of acute coronary events in premenopausal women.
Am J Med
; 114(7): 599-602, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12753884