Detalhe da pesquisa
1.
Mitochondrial translocation of TFEB regulates complex I and inflammation.
EMBO Rep
; 25(2): 704-724, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38263327
2.
Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.
Blood
; 139(26): 3737-3751, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35443029
3.
Slit-Robo signalling establishes a Sphingosine-1-phosphate gradient to polarise fin mesenchyme.
EMBO Rep
; 23(8): e54464, 2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35679135
4.
Targeting Acute Myeloid Leukemia Using Sphingosine Kinase 1 Inhibitor-Loaded Liposomes.
Mol Pharm
; 20(8): 3937-3946, 2023 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37463151
5.
Integrated in silico and experimental assessment of disease relevance of PCDH19 missense variants.
Hum Mutat
; 42(8): 1030-1041, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34082468
6.
Kelch-like protein 5-mediated ubiquitination of lysine 183 promotes proteasomal degradation of sphingosine kinase 1.
Biochem J
; 476(21): 3211-3226, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31652307
7.
In vitro and in vivo roles of sphingosine kinase 2 during dengue virus infection.
J Gen Virol
; 100(4): 629-641, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30869582
8.
Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.
Blood
; 129(6): 771-782, 2017 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27956387
9.
Topical Application of Fingolimod Perturbs Cutaneous Inflammation.
J Immunol
; 196(9): 3854-64, 2016 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27001955
10.
Identifying natural substrates for dipeptidyl peptidases 8 and 9 using terminal amine isotopic labeling of substrates (TAILS) reveals in vivo roles in cellular homeostasis and energy metabolism.
J Biol Chem
; 288(20): 13936-13949, 2013 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23519473
11.
The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism.
Sci Rep
; 12(1): 454, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35013382
12.
Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition.
Neoplasia
; 24(1): 1-11, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34826777
13.
Hydrophilic residues surrounding the S1 and S2 pockets contribute to dimerisation and catalysis in human dipeptidyl peptidase 8 (DP8).
Biol Chem
; 391(8): 959-72, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20536396
14.
Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma.
Oncogene
; 38(8): 1151-1165, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30250299
15.
Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8.
FEBS Lett
; 582(5): 819-25, 2008 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18275857
16.
An Improved Isoform-Selective Assay for Sphingosine Kinase 1 Activity.
Methods Mol Biol
; 1697: 9-20, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-28540558
17.
Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD.
PLoS One
; 12(11): e0179577, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29112690
18.
CIB2 Negatively Regulates Oncogenic Signaling in Ovarian Cancer via Sphingosine Kinase 1.
Cancer Res
; 77(18): 4823-4834, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28729416
19.
Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress.
Oncotarget
; 8(27): 43602-43616, 2017 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28467788
20.
Recent advances in the development of sphingosine kinase inhibitors.
Cell Signal
; 28(9): 1349-1363, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27297359