Detalhe da pesquisa
1.
Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases.
PLoS Genet
; 16(1): e1008538, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31917787
2.
Coronary Disease-Associated Gene TCF21 Inhibits Smooth Muscle Cell Differentiation by Blocking the Myocardin-Serum Response Factor Pathway.
Circ Res
; 126(4): 517-529, 2020 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31815603
3.
Environment-Sensing Aryl Hydrocarbon Receptor Inhibits the Chondrogenic Fate of Modulated Smooth Muscle Cells in Atherosclerotic Lesions.
Circulation
; 142(6): 575-590, 2020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32441123
4.
Genetic Regulatory Mechanisms of Smooth Muscle Cells Map to Coronary Artery Disease Risk Loci.
Am J Hum Genet
; 103(3): 377-388, 2018 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30146127
5.
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk.
PLoS Genet
; 14(10): e1007681, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30307970
6.
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.
PLoS Genet
; 14(11): e1007755, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30444878
7.
Advances in Transcriptomics: Investigating Cardiovascular Disease at Unprecedented Resolution.
Circ Res
; 122(9): 1200-1220, 2018 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29700068
8.
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells.
PLoS Genet
; 13(5): e1006750, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28481916
9.
CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation.
BMC Endocr Disord
; 19(1): 115, 2019 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31664995
10.
Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci.
PLoS Genet
; 11(5): e1005202, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26020271
11.
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap.
PLoS Genet
; 11(5): e1005155, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26020946
12.
Genetics and Genomics of Coronary Artery Disease.
Curr Cardiol Rep
; 18(10): 102, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27586139
13.
Nuclear Factor I genomic binding associates with chromatin boundaries.
BMC Genomics
; 14: 99, 2013 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23402308
14.
Nuclear factor I revealed as family of promoter binding transcription activators.
BMC Genomics
; 12: 181, 2011 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21473784
15.
From Locus Association to Mechanism of Gene Causality: The Devil Is in the Details.
Arterioscler Thromb Vasc Biol
; 35(10): 2079-2080, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26399919
16.
Molecular mechanisms of coronary disease revealed using quantitative trait loci for TCF21 binding, chromatin accessibility, and chromosomal looping.
Genome Biol
; 21(1): 135, 2020 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32513244
17.
TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression.
Genome Med
; 11(1): 23, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31014396
18.
Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation.
iScience
; 20: 42-59, 2019 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31557715
19.
Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis.
Nat Med
; 25(8): 1280-1289, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31359001
20.
The role of polycarbonate monomer bisphenol-A in insulin resistance.
PeerJ
; 5: e3809, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28929027