Pesquisa | Biblioteca Virtual em Saúde

1.

Sustained remissions in CLL after frontline FCR treatment with very-long-term follow-up.

Thompson, Philip A; Bazinet, Alexandre; Wierda, William G; Tam, Constantine S; O'Brien, Susan M; Saha, Satabdi; Peterson, Christine B; Plunkett, William; Keating, Michael J.

Blood ; 142(21): 1784-1788, 2023 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-37595283

2.

Ibrutinib and Venetoclax for First-Line Treatment of CLL.

Jain, Nitin; Keating, Michael; Thompson, Philip; Ferrajoli, Alessandra; Burger, Jan; Borthakur, Gautam; Takahashi, Koichi; Estrov, Zeev; Fowler, Nathan; Kadia, Tapan; Konopleva, Marina; Alvarado, Yesid; Yilmaz, Musa; DiNardo, Courtney; Bose, Prithviraj; Ohanian, Maro; Pemmaraju, Naveen; Jabbour, Elias; Sasaki, Koji; Kanagal-Shamanna, Rashmi; Patel, Keyur; Jorgensen, Jeffrey; Garg, Naveen; Wang, Xuemei; Sondermann, Katrina; Cruz, Nichole; Wei, Chongjuan; Ayala, Ana; Plunkett, William; Kantarjian, Hagop; Gandhi, Varsha; Wierda, William.

N Engl J Med ; 380(22): 2095-2103, 2019 05 30.

Artigo em Inglês | MEDLINE | ID: mdl-31141631

3.

Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.

Luo, Yongde; Yang, Yaying; Liu, Muyun; Wang, Dan; Wang, Feng; Bi, Yawei; Ji, Juntao; Li, Suyun; Liu, Yan; Chen, Rong; Huang, Haojie; Wang, Xiaojie; Swidnicka-Siergiejko, Agnieszka K; Janowitz, Tobias; Beyaz, Semir; Wang, Guoqiang; Xu, Sulan; Bialkowska, Agnieszka B; Luo, Catherine K; Pin, Christoph L; Liang, Guang; Lu, Xiongbin; Wu, Maoxin; Shroyer, Kenneth R; Wolff, Robert A; Plunkett, William; Ji, Baoan; Li, Zhaoshen; Li, Ellen; Li, Xiaokun; Yang, Vincent W; Logsdon, Craig D; Abbruzzese, James L; Lu, Weiqin.

Gastroenterology ; 157(5): 1413-1428.e11, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31352001

4.

Phase 1/2 study of DFP-10917 administered by continuous intravenous infusion in patients with recurrent or refractory acute myeloid leukemia.

Kantarjian, Hagop M; Jabbour, Elias J; Garcia-Manero, Guillermo; Kadia, Tapan M; DiNardo, Courtney D; Daver, Naval G; Borthakur, Gautam; Jain, Nitin; Waukau, Jane B; Kwari, Monica I; Ravandi, Farhad; Anderson, Barry D; Iizuka, Kenzo; Jin, Cheng; Zhang, Chun; Plunkett, William K.

Cancer ; 125(10): 1665-1673, 2019 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-30668890

5.

Fludarabine, cyclophosphamide, and rituximab treatment achieves long-term disease-free survival in IGHV-mutated chronic lymphocytic leukemia.

Thompson, Philip A; Tam, Constantine S; O'Brien, Susan M; Wierda, William G; Stingo, Francesco; Plunkett, William; Smith, Susan C; Kantarjian, Hagop M; Freireich, Emil J; Keating, Michael J.

Blood ; 127(3): 303-9, 2016 Jan 21.

Artigo em Inglês | MEDLINE | ID: mdl-26492934

6.

Targeting BTK through microRNA in chronic lymphocytic leukemia.

Bottoni, Arianna; Rizzotto, Lara; Lai, Tzung-Huei; Liu, Chaomei; Smith, Lisa L; Mantel, Rose; Reiff, Sean; El-Gamal, Dalia; Larkin, Karilyn; Johnson, Amy J; Lapalombella, Rosa; Lehman, Amy; Plunkett, William; Byrd, John C; Blachly, James S; Woyach, Jennifer A; Sampath, Deepa.

Blood ; 128(26): 3101-3112, 2016 12 29.

Artigo em Inglês | MEDLINE | ID: mdl-27756747

7.

A randomized phase 2 study of idarubicin and cytarabine with clofarabine or fludarabine in patients with newly diagnosed acute myeloid leukemia.

Jabbour, Elias; Short, Nicholas J; Ravandi, Farhad; Huang, Xuelin; Xiao, Lianchun; Garcia-Manero, Guillermo; Plunkett, William; Gandhi, Varsha; Sasaki, Koji; Pemmaraju, Naveen; Daver, Naval G; Borthakur, Gautam; Jain, Nitin; Konopleva, Marina; Estrov, Zeev; Kadia, Tapan M; Wierda, William G; DiNardo, Courtney D; Brandt, Mark; O'Brien, Susan M; Cortes, Jorge E; Kantarjian, Hagop.

Cancer ; 123(22): 4430-4439, 2017 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-28708931

8.

Arginine addiction in AML.

Plunkett, William.

Blood ; 125(26): 3971-2, 2015 Jun 25.

Artigo em Inglês | MEDLINE | ID: mdl-26113532

9.

Long-term results of first salvage treatment in CLL patients treated initially with FCR (fludarabine, cyclophosphamide, rituximab).

Tam, Constantine S; O'Brien, Susan; Plunkett, William; Wierda, William; Ferrajoli, Alessandra; Wang, Xuemei; Do, Kim-Anh; Cortes, Jorge; Khouri, Issa; Kantarjian, Hagop; Lerner, Susan; Keating, Michael J.

Blood ; 124(20): 3059-64, 2014 Nov 13.

Artigo em Inglês | MEDLINE | ID: mdl-25281606

10.

Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe.

Jouanneau, Morgan; McClary, Brandon; Reyes, Jeremy Chris P; Chen, Rong; Chen, Yuling; Plunkett, William; Cheng, Xin; Milinichik, Andrew Z; Albone, Earl F; Liu, Jun O; Romo, Daniel.

Bioorg Med Chem Lett ; 26(8): 2092-7, 2016 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-26951751

11.

TRIM24 links a non-canonical histone signature to breast cancer.

Tsai, Wen-Wei; Wang, Zhanxin; Yiu, Teresa T; Akdemir, Kadir C; Xia, Weiya; Winter, Stefan; Tsai, Cheng-Yu; Shi, Xiaobing; Schwarzer, Dirk; Plunkett, William; Aronow, Bruce; Gozani, Or; Fischle, Wolfgang; Hung, Mien-Chie; Patel, Dinshaw J; Barton, Michelle Craig.

Nature ; 468(7326): 927-32, 2010 Dec 16.

Artigo em Inglês | MEDLINE | ID: mdl-21164480

12.

Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer.

Koay, Eugene J; Baio, Flavio E; Ondari, Alexander; Truty, Mark J; Cristini, Vittorio; Thomas, Ryan M; Chen, Rong; Chatterjee, Deyali; Kang, Ya'an; Zhang, Joy; Court, Laurence; Bhosale, Priya R; Tamm, Eric P; Qayyum, Aliya; Crane, Christopher H; Javle, Milind; Katz, Matthew H; Gottumukkala, Vijaya N; Rozner, Marc A; Shen, Haifa; Lee, Jeffrey E; Wang, Huamin; Chen, Yuling; Plunkett, William; Abbruzzese, James L; Wolff, Robert A; Maitra, Anirban; Ferrari, Mauro; Varadhachary, Gauri R; Fleming, Jason B.

Phys Biol ; 11(6): 065002, 2014 Nov 26.

Artigo em Inglês | MEDLINE | ID: mdl-25427073

13.

Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia.

Chen, Rong; Guo, Lei; Chen, Yuling; Jiang, Yingjun; Wierda, William G; Plunkett, William.

Blood ; 117(1): 156-64, 2011 Jan 06.

Artigo em Inglês | MEDLINE | ID: mdl-20971952

14.

Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study.

Kantarjian, Hagop; Faderl, Stefan; Garcia-Manero, Guillermo; Luger, Selina; Venugopal, Parameswaran; Maness, Lori; Wetzler, Meir; Coutre, Steven; Stock, Wendy; Claxton, David; Goldberg, Stuart L; Arellano, Martha; Strickland, Stephen A; Seiter, Karen; Schiller, Gary; Jabbour, Elias; Chiao, Judy; Plunkett, William.

Lancet Oncol ; 13(11): 1096-104, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23075701

15.

Homologous recombination as a resistance mechanism to replication-induced double-strand breaks caused by the antileukemia agent CNDAC.

Liu, Xiaojun; Wang, Yaqing; Benaissa, Sherri; Matsuda, Akira; Kantarjian, Hagop; Estrov, Zeev; Plunkett, William.

Blood ; 116(10): 1737-46, 2010 Sep 09.

Artigo em Inglês | MEDLINE | ID: mdl-20479284

16.

microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival.

Rossi, Simona; Shimizu, Masayoshi; Barbarotto, Elisa; Nicoloso, Milena S; Dimitri, Federica; Sampath, Deepa; Fabbri, Muller; Lerner, Susan; Barron, Lynn L; Rassenti, Laura Z; Jiang, Li; Xiao, Lianchun; Hu, Jianhua; Secchiero, Paola; Zauli, Giorgio; Volinia, Stefano; Negrini, Massimo; Wierda, William; Kipps, Thomas J; Plunkett, William; Coombes, Kevin R; Abruzzo, Lynne V; Keating, Michael J; Calin, George A.

Blood ; 116(6): 945-52, 2010 Aug 12.

Artigo em Inglês | MEDLINE | ID: mdl-20393129

17.

Sapacitabine, the prodrug of CNDAC, is a nucleoside analog with a unique action mechanism of inducing DNA strand breaks.

Liu, Xiao-Jun; Nowak, Billie; Wang, Ya-Qing; Plunkett, William.

Chin J Cancer ; 31(8): 373-80, 2012 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-22739266

18.

Cyclin-dependent kinase inhibitor fadraciclib (CYC065) depletes anti-apoptotic protein and synergizes with venetoclax in primary chronic lymphocytic leukemia cells.

Chen, Rong; Chen, Yuling; Xiong, Ping; Zheleva, Daniella; Blake, David; Keating, Michael J; Wierda, William G; Plunkett, William.

Leukemia ; 36(6): 1596-1608, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35383271

19.

DNA-dependent protein kinase and ataxia telangiectasia mutated (ATM) promote cell survival in response to NK314, a topoisomerase IIα inhibitor.

Guo, Lei; Liu, Xiaojun; Jiang, Yingjun; Nishikawa, Kiyohiro; Plunkett, William.

Mol Pharmacol ; 80(2): 321-7, 2011 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-21546556

20.

Intracellular succinylation of 8-chloroadenosine and its effect on fumarate levels.

Dennison, Jennifer B; Ayres, Mary L; Kaluarachchi, Kumar; Plunkett, William; Gandhi, Varsha.

J Biol Chem ; 285(11): 8022-30, 2010 Mar 12.

Artigo em Inglês | MEDLINE | ID: mdl-20064937

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