Detalhe da pesquisa
1.
Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.
Nat Immunol
; 19(12): 1299-1308, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30374129
2.
A Randomized Controlled Clinical Trial of Nasal Immunization with Live Virulence Attenuated Streptococcus pneumoniae Strains Using Human Infection Challenge.
Am J Respir Crit Care Med
; 208(8): 868-878, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37556679
3.
Human Infection Challenge with Serotype 3 Pneumococcus.
Am J Respir Crit Care Med
; 206(11): 1379-1392, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802840
4.
Targeted Transcriptomic Screen of Pneumococcal Genes Expressed during Murine and Human Infection.
Infect Immun
; 90(7): e0017522, 2022 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35674445
5.
Experimental Human Pneumococcal Colonization in Older Adults Is Feasible and Safe, Not Immunogenic.
Am J Respir Crit Care Med
; 203(5): 604-613, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32941735
6.
Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens.
Am J Respir Crit Care Med
; 201(3): 335-347, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31626559
7.
Pneumococcal Colonization in Healthy Adult Research Participants in the Conjugate Vaccine Era, United Kingdom, 2010-2017.
J Infect Dis
; 219(12): 1989-1993, 2019 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30690468
8.
Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage.
Am J Respir Crit Care Med
; 194(12): 1523-1531, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27403678
9.
Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis.
Neurobiol Dis
; 75: 131-41, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25555543
10.
Hands are vehicles for transmission of Streptococcus pneumoniae in novel controlled human infection study.
Eur Respir J
; 52(4)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30305331
11.
Participant perceptions and experiences of a novel community-based respiratory longitudinal sampling method in Liverpool, UK: A mixed methods feasibility study.
PLoS One
; 18(11): e0294133, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37943741
12.
Influence of sex, season and environmental air quality on experimental human pneumococcal carriage acquisition: a retrospective cohort analysis.
ERJ Open Res
; 8(2)2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35415189
13.
Protocol for a phase IV double-blind randomised controlled trial to investigate the effect of the 13-valent pneumococcal conjugate vaccine and the 23-valent pneumococcal polysaccharide vaccine on pneumococcal colonisation using the experimental human pneumococcal challenge model in healthy adults (PREVENTING PNEUMO 2).
BMJ Open
; 12(7): e062109, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35798520
14.
Streptococcus pneumoniae colonization associates with impaired adaptive immune responses against SARS-CoV-2.
J Clin Invest
; 132(7)2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35139037
15.
Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine.
JCI Insight
; 6(4)2021 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33497364
16.
Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults.
mBio
; 12(1)2021 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33436429
17.
The nose is the best niche for detection of experimental pneumococcal colonisation in adults of all ages, using nasal wash.
Sci Rep
; 11(1): 18279, 2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34521967
18.
Symptoms associated with influenza vaccination and experimental human pneumococcal colonisation of the nasopharynx.
Vaccine
; 38(10): 2298-2306, 2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32035708
19.
Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface.
Nat Commun
; 10(1): 3060, 2019 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31311921
20.
Minimally Invasive Nasal Sampling in Children Offers Accurate Pneumococcal Colonization Detection.
Pediatr Infect Dis J
; 38(11): 1147-1149, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31577644