RESUMO
In this review we analyzed the guidelines for diagnosis and management of celiac disease, as well as the recent studies published on this issue. Capsule endoscopy could be used in patients unwilling or unable to undergo conventional endoscopy, in patients who have discordant results between serological and histopathological investigation, in patients with nonresponsive or refractory celiac disease.
Assuntos
Endoscopia por Cápsula/métodos , Doença Celíaca/diagnóstico , Intestino Delgado/diagnóstico por imagem , Guias de Prática Clínica como Assunto , HumanosRESUMO
AIM: To assess the efficacy of transcranial electrostimulation TES for treatmnet of anxiety-like behavior and motor disorders in rats with rotenone-induced parkinsonism. MATERIAL AND METHODS: The study was performed on 30 mature male-rats. Animals were divided into following groups: control, intact rats (group 1); rats with an experimental model of parkinsonism without treatment (group 2); rats with an experimental model of parkinsonism, which had 7 sessions of TES-therapy (group 3), the number of rats in each group was 10. The parkinsonism model was achieved by daily rotenone administration for 28 days. Parkinsonism's markers were assessed using 3-point scale; anxiety-like behavior and motor activity were assessed in the open-field test. TES was performed using TRANSAIR-stimulator for 7 days. Substantia nigra slices were stained with hematoxylin and Lillie's staining for neuromelanin. RESULTS: The rats of group 3 show less neurological deficits, less anxiety-like behavior and less neurodegeneration in the substantia nigra. There are a decrease in individual total scores of motor disorders by 50%, a decrease in the level of anxiety-like behavior or the absence of its increase in the open-field test. CONCLUSION: TES-therapy may be used as an additional non-pharmacological treatment of motor and related non-motor damage in Parkinson's disease.