RESUMO
Gastric cancer is one of the most frequent worldwide. Brain metastases from gastric cancer are rare and are diagnosed in less than 1% of patients with gastric cancer. We present the case of a 61-year-old woman with a history of decreased visual acuity, headache, and involuntary movements. She underwent an MRI that showed a left occipital extraparenchymal appearance lesion. The PET scan reveals a hypermetabolic zone in the lesser curvature of the stomach, and the endoscopy reveals a lesion suggestive of gastric malignant neoplasia in the Borrmann I fundus. It was decided to perform a tumor excision by neurosurgery, whose pathological anatomy study revealed metastatic adenocarcinoma to the brain. She undergoes a total D2 gastrectomy, no other metastases are evident. The patient evolves favorably in the postoperative period. The pathology study revealed a poorly differentiated adenocarcinoma. In Peru and in the world, standard recommendations on how to treat these patients have not yet been established, although it is known that surgical resection of brain metastases can significantly decrease morbidity and prolong survival compared to non-surgical approaches. As far as we know, it is the first report of this type presented in the country.
Assuntos
Adenocarcinoma , Neoplasias Encefálicas , Neoplasias Gástricas , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias Gástricas/patologia , Gastrectomia , Adenocarcinoma/patologia , Neoplasias Encefálicas/cirurgia , EndoscopiaRESUMO
The primary intestinal follicular lymphoma is a rare disease described in the last classification of lymphomas from WHO. It is a localized disease with excellent prognosis. We describe in this article ,a 64 year-old Peruvian female with abdominal pain and delayed vomiting for the last two years, has undergone a partial intestinal resection due to bowel obstruction. There was a well-circumscribed annular tumor. A diagnosis of non-polypoid primary intestinal follicular lymphoma was made. We report the case and review the literature in this article.
Assuntos
Neoplasias do Jejuno/diagnóstico , Jejuno/patologia , Linfoma Folicular/diagnóstico , Biópsia , Feminino , Humanos , Neoplasias do Jejuno/patologia , Linfoma Folicular/patologia , Pessoa de Meia-IdadeRESUMO
INTRODUCTION: There is epidemiologic evidence that suggest the relation between the histological type and location of gastric adenocarcinoma. Knowing that there is a predominance of Helicobacter pylori infection in the antral region and this is considered an environmental factor; make us suppose that there is a relation among intestinal type and distal location. OBJECTIVE: The aim of this study is to investigate the relation among histological type and location of gastric cancer, using the Lauren classification and the Japanese Gastric Cancer Association classification. METHOD: During the period between January 1st 2007 and December 31th 2010, 460 patients with the proven diagnostic of adenocarcinoma were admitted for surgical treatment at the gastric cancer specialized ward of Rebagliati National Hospital, Lima, Peru. RESULTS: Female was more frequent in diffuse type (39% vs. 33%; p: 0,153), the mean age among intestinal type is greater than diffuse type (70,7 vs. 62,6 años; p<0,001). There is association among poorly differentiated with upper location (22% vs. 12,7%; p = 0,009), signet cell with middle location (50% vs. 32,5%; p: 0,006), tubular type with distal location (57,6% vs. 42,8%; p: 0,002), intestinal type with distal location (58,3% vs. 44,1%; p: 0,004), and diffuse type with upper location (19,3% vs. 12,5%; p: 0,049). CONCLUSION: Adenocarcinomas histologically differentiated or intestinal type are associated with distal location. Poorly differentiated type and signet ring cell type are associated with upper and middle location respectively.
Assuntos
Adenocarcinoma/patologia , Neoplasias Gástricas/patologia , Adenocarcinoma/classificação , Adenocarcinoma/epidemiologia , Adenocarcinoma Mucinoso/epidemiologia , Adenocarcinoma Mucinoso/patologia , Adenocarcinoma Papilar/epidemiologia , Adenocarcinoma Papilar/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Carcinoma de Células em Anel de Sinete/epidemiologia , Carcinoma de Células em Anel de Sinete/patologia , Cárdia/patologia , Feminino , Fundo Gástrico/patologia , Hospitais Públicos/estatística & dados numéricos , Hospitais Urbanos/estatística & dados numéricos , Humanos , Masculino , Metaplasia , Pessoa de Meia-Idade , Peru/epidemiologia , Antro Pilórico/patologia , Neoplasias Gástricas/classificação , Neoplasias Gástricas/epidemiologiaRESUMO
BACKGROUND: Esophagojejunal fistula is a serious complication after total gastrectomy in gastric cancer patients. This study describes the successful conservative management in 3 gastric cancer patients with esophagojejunal fistula after total gastrectomy using total enteral nutrition. METHODS: Between January 2004 to December 2008, 588 consecutive patients with a proven diagnosis of gastric cancer were taken to the operation room to try a curative treatment. Of these, 173 underwent total gastrectomy, 9 of them had esophagojejunal fistula (5.2%). In three selected patients a trans-anastomotic naso-enteral feeding tube was placed under fluoroscopic vision when the fistula was clinically detected and a complete polymeric enteral formula was used. RESULTS: The complete closing of the esophagojejunal fistula was obtained in day 8, 14 and 25 respectively. CONCLUSION: In some selected cases it is possible to make a successful enteral nutrition using a feeding tube distal to the leak area inserted with the help of fluoroscopic vision. The specialized management of a gastric surgery unit and nutritional therapy unit are highlighted.
Assuntos
Nutrição Enteral , Fístula Esofágica/terapia , Gastrectomia/efeitos adversos , Doenças do Jejuno/terapia , Complicações Pós-Operatórias/prevenção & controle , Neoplasias Gástricas/cirurgia , Fístula Esofágica/etiologia , Humanos , Doenças do Jejuno/etiologia , Cuidados Pós-Operatórios , Resultado do TratamentoRESUMO
This report describes the characteristics of early gastric cancer surgically treated in the Gastric Cancer Unit at Rebagliati National Hospital between January 2004 and December 2008. Mean age was 68 years; males, distal location, submucosa infiltration and intestinal histological type predominate in these patients. Lymph node involvement was 13%.
Assuntos
Carcinoma/cirurgia , Hospitais Públicos/estatística & dados numéricos , Neoplasias Gástricas/cirurgia , Idoso , Carcinoma/epidemiologia , Carcinoma/patologia , Diferenciação Celular , Feminino , Gastrectomia/métodos , Gastrectomia/estatística & dados numéricos , Humanos , Metástase Linfática , Masculino , Metaplasia , Pessoa de Meia-Idade , Invasividade Neoplásica , Estadiamento de Neoplasias , Peru/epidemiologia , Estudos Retrospectivos , Neoplasias Gástricas/epidemiologia , Neoplasias Gástricas/patologiaRESUMO
El cáncer gástrico es uno de los más frecuentes a nivel mundial. Las metástasis cerebrales por cáncer gástrico son poco frecuentes y se diagnostican en menos del 1% de los pacientes. Presentamos el caso de una mujer de 61 años con historia de disminución de la agudeza visual, cefalea y movimientos involuntarios. Le realizan una resonancia magnética que muestra una lesión de apariencia extraparenquimal occipital izquierda. El PET scan revela una zona hipermetabólica en curvatura menor del estómago, y la endoscopia evidencia una lesión sugerente de neoplasia maligna en fondo gástrico Borrmann I. Se decide realizar una excéresis tumoral por neurocirugía, cuyo estudio de anatomía patológica reveló adenocarcinoma metastásico a cerebro. Se le realiza una gastrectomía total D2, no se evidencian otras metástasis. La paciente evoluciona favorablemente en el postoperatorio. El estudio anatomopatológico revelo adenocarcinoma pobremente diferenciado. En Perú y en el mundo, aún no se han establecido recomendaciones estándar sobre cómo tratar a estos pacientes, aunque se sabe que la resección quirúrgica de metástasis cerebrales puede disminuir significativamente la morbilidad y prolongar la supervivencia en comparación con los enfoques no quirúrgicos. Hasta donde sabemos, es el primer reporte de este tipo que se presenta en el país.
Gastric cancer is one of the most frequent worldwide. Brain metastases from gastric cancer are rare and are diagnosed in less than 1% of patients with gastric cancer. We present the case of a 61-year-old woman with a history of decreased visual acuity, headache, and involuntary movements. She underwent an MRI that showed a left occipital extraparenchymal appearance lesion. The PET scan reveals a hypermetabolic zone in the lesser curvature of the stomach, and the endoscopy reveals a lesion suggestive of gastric malignant neoplasia in the Borrmann I fundus. It was decided to perform a tumor excision by neurosurgery, whose pathological anatomy study revealed metastatic adenocarcinoma to the brain. She undergoes a total D2 gastrectomy, no other metastases are evident. The patient evolves favorably in the postoperative period. The pathology study revealed a poorly differentiated adenocarcinoma. In Peru and in the world, standard recommendations on how to treat these patients have not yet been established, although it is known that surgical resection of brain metastases can significantly decrease morbidity and prolong survival compared to non-surgical approaches. As far as we know, it is the first report of this type presented in the country.
RESUMO
Los lipomas gástricos son una patología muy rara que representan el 5% de los lipomas gastrointestinales y menos del 1% de los tumores benignos del estómago. Los lipomas gástricos gigantes (≥ 4 cm) son extremadamente raros, habiéndose encontrado solo 32 casos reportados en la bibliografía. Reportamos el primer caso de un lipoma gástrico gigante en el Perú, operado por gastrectomía corporal por laparotomía en una paciente mujer de 79 años que acudió con un cuadro clínico de dos meses de evolución caracterizado por dolor abdominal en epigastrio más sensación de llenura precoz, deposiciones oscuras y pérdida de peso. Al examen físico se halló una masa palpable de aproximadamente 8 cm en hipocondrio izquierdo. La endoscopía digestiva alta reveló una lesión elevada en el tercio proximal del cuerpo gástrico de aproximadamente 30 mm. Se realizó un estudio tomográfico que evidenció una masa sospechosa de lipoma gástrico por lo que se procedió a realizar una gastrectomía corporal por laparotomía. El informe anatomopatológico confirmó el diagnóstico de lipoma gástrico gigante. En el posoperatorio no hubo complicaciones y fue dada de alta al séptimo día.
Gastric lipoma is a very rare condition, which accounts for 5% of gastrointestinal lipomas and for less than 1% of benign tumors of the stomach. Giant gastric lipomas (≥ 4 cm) are extremely rare, and we found only 32 cases reported in the literature. We report the first case of a giant gastric lipoma in Peru, which led to a corporal gastrectomy using a laparotomy approach in a 79-year old woman, who presented with a 2-month history with abdominal and epigastric pain, early fullness, dark stools, and weight loss. Physical examination revealed a 7- to 8-cm palpable mass in the left upper quadrant. Upper gastrointestinal endoscopy revealed an elevated lesion in the proximal third of the gastric body, measuring approximately 30-mm. A CT scan revealed a mass compatible with a gastric lipoma, so a corporal gastrectomy with a laparotomy approach was performed. The anatomopathological report confirmed the diagnosis of a giant gastric lipoma. There were no complications during the postoperative period, and the patient was discharged on the seventh post-op day.
RESUMO
El linfoma folicular primario intestinal es un desorden raro descrito en la última clasificación de linfomas de la WHO. Es una entidad localizada con excelente pronóstico. En el presente artículo, reportamos una mujer peruana de 64 años de edad diagnosticada con linfoma folicular primario intestinal. Ella tuvo dos años con dolor abdominal y vómitos tardíos. Ella desarrolló una obstrucción intestinal y tuvo una resección completa del tumor. Se describe el caso y se realiza una revisión de la literatura de esta entidad.
The primary intestinal follicular lymphoma is a rare disease described in the last classification of lymphomas from WHO. It is a localized disease with excellent prognosis. We describe in this article ,a 64 year-old Peruvian female with abdominal pain and delayed vomiting for the last two years, has undergone a partial intestinal resection due to bowel obstruction. There was a well-circumscribed annular tumor. A diagnosis of non-polypoid primary intestinal follicular lymphoma was made. We report the case and review the literature in this article.
Assuntos
Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Tromboembolia Venosa/etiologia , Tromboembolia Venosa/prevenção & controle , Estudos Transversais , Coleta de Dados , Fidelidade a Diretrizes , Irã (Geográfico) , Medição de Risco , Fatores de RiscoRESUMO
Endoscopic submucosal dissection is a new treatment, basically for the management of early gastric cancer, it is also a good option for large benign lesions if a "una pieza" resection needs to be performed. However this technique requires not only gastroenterologist with proven technical skill, but also some special devices not necessarily disposables in our country. The present paper describes the case of a patient with a large hyperplastic polyp located in the upper third of the stomach who underwent an open endoscopic submucosal dissection to resect the lesion owing to its size and characteristics. According our knowledge this is the first case in the medical literature describing the use of this technique during an open surgery.
Assuntos
Gastroscopia , Pólipos/cirurgia , Neoplasias Gástricas/cirurgia , Idoso , Procedimentos Cirúrgicos do Sistema Digestório/métodos , Feminino , HumanosRESUMO
BACKGROUND: The best results in the surgical treatment of gastric cancer are those obtained by the Japanese surgical school that emphasizes D2 lymphadenectomy as a fundamental principle for obtaining better local control of the disease. However, this technique has not gained wide acceptance in the West, owing to the fact that the results of Japanese studies have not been reproduced frequently in Western countries. In recent years, a series of studies have recommended the centralization of gastric cancer treatment in specialized surgical units in order to obtain results similar to those achieved by Japanese centers. The objective of this study was to describe the specialization process and to show the short-term results obtained in the surgical treatment of gastric cancer in the Specialized Unit of the Rebagliati National Hospital, the largest general referral hospital in Lima, Peru. METHODS: In the year 2000 a specialized service was created for the surgical treatment of gastric cancer, initiating a process that included the establishment of surgical treatment guidelines, training in the Japanese surgical technique, and progress along the learning curve for D2 lymphadenectomy. Clinical, surgical, and pathological data were recorded prospectively in a fixed format, considering that strict documentation of cases was also an important step within this process. RESULTS: Between January 1, 2004, and December 31, 2005, 243 consecutive patients with a proven diagnosis of gastric adenocarcinoma were admitted to the operating theater for surgical treatment. During this study period, morbidity was 22.7% and hospital mortality, 2.8%. The numbers (mean +/- SD) of resected lymph nodes for distal gastrectomy and total gastrectomy were 37.3 +/- 12.4 and 45.3 +/- 14.5, respectively. Hospital stay was 13 days for distal gastrectomy as well as for total gastrectomy. CONCLUSION: According to our results, adequate training in the Japanese surgical technique, progress along the learning curve for D2 lymphadenectomy, and the establishment of specialized units are highly recommended for the surgical treatment of gastric cancer in Western referral hospitals.
Assuntos
Adenocarcinoma/cirurgia , Institutos de Câncer , Excisão de Linfonodo , Especialidades Cirúrgicas , Neoplasias Gástricas/cirurgia , Adenocarcinoma/mortalidade , Adulto , Idoso , Idoso de 80 Anos ou mais , Europa (Continente) , Feminino , Mortalidade Hospitalar , Humanos , Japão , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Peru , Complicações Pós-Operatórias , Estudos Prospectivos , Neoplasias Gástricas/mortalidade , Centro Cirúrgico HospitalarRESUMO
Gastrectomy with D2 lymphadenectomy is the standard surgical procedure in most hospitals in Peru due to the fact that this Japanese surgical technique has proven to provide the best results in the world. However, no comparative study of the results of D1 and D2 lymphadenectomies has ever been performed in our country. This retrospective cohort study compares D2 lymphadenectomy versus D1 in surgical treatment of gastric cancer.Between January 2000 and December 2002, 316 patients underwent surgery at the Rebagliati National Hospital and a total of 100 patients were randomly selected, 50 of which underwent a D1 lymphadenectomy and 50 a D2 lymphadenectomy. Mortality rates were 8% for D1 lymphadenectomy and 4% for D2, whereas morbidityrates were 24% for D1 and 12% for D2. Survival after 3 years was 36% for D1 and 56% for D2 thus establishing a statistically significant difference (p = 0.04). We recommend gastrectomy with D2 lymphadenectomy as the surgical treatment of choice for advanced gastric cancer.
Assuntos
Gastrectomia/métodos , Excisão de Linfonodo/métodos , Neoplasias Gástricas/cirurgia , Idoso , Dissecação , Feminino , Humanos , Metástase Linfática/patologia , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Estudos Retrospectivos , Neoplasias Gástricas/mortalidade , Neoplasias Gástricas/patologia , Análise de SobrevidaRESUMO
INTRODUCCIÓN: Existe evidencia epidemiológica que sugiere la asociación entre un tipo histológico y la localización del adenocarcinoma gástrico. Sabiendo que existe un predominio de infección por Helicobacter pylori en la región antral y ésta es considerada como un factor ambiental, es válido sospechar la existencia de una relación entre el tipo histológico intestinal y la localización distal. OBJETIVO: El objetivo de este estudio es investigar la relación entre el tipo histológico y la localización del cáncer gástrico, utilizando la clasificación propuesta por la Asociación Japonesa de Cáncer Gástrico y la clasificación propuesta por Lauren. MATERIALES Y MÉTODO: durante el periodo de Enero 2007 a Diciembre 2010, 460 pacientes con diagnostico probado de adenocarcinoma admitidos en el Servicio especializado de Cirugía de Estómago del Hospital Rebagliati parta tratamiento quirúrgico. RESULTADOS: El sexo femenino fue más frecuente en el tipo difuso (39 por ciento vs 33 por ciento; p: 0,153), la media de edad en el tipo intestinal es mayor al tipo difuso (70,7 vs 62,6 años; p<0,001). Existe asociación entre el tipo histológico pobremente diferenciado con la localización proximal (22 por ciento vs 12,7 por ciento; p: 0,009), el tipo de células en anillo de sello con la localización media (50 por ciento vs 32,5 por ciento; p: 0,006), el tubular con la localización distal (57,6 por ciento vs 42,8 por ciento; p: 0,002), el tipo intestinal con la localización distal (58,3 por ciento vs 44,1 por ciento; p: 0,004), y el difuso con la localización proximal (19,3 por ciento vs 12,5 por ciento; p: 0,049). CONCLUSIÓN: Los adenocarcinomas de tipo diferenciado ó de tipo intestinal están asociados con la localización distal. Los pobremente diferenciados y con células en anillo de sello se asocian con la localización proximal y media respectivamente.
INTRODUCTION: There is epidemiologic evidence that suggest the relation between the histological type and location of gastric adenocarcinoma. Knowing that there is a predominance of Helicobacter pylori infection in the antral region and this is considered an environmental factor; make us suppose that there is a relation among intestinal type and distal location. OBJECTIVE: The aim of this study is to investigate the relation among histological type and location of gastric cancer, using the Lauren classification and the Japanese Gastric Cancer Association classification. METHOD: During the period between January 1st 2007 and December 31th 2010, 460 patients with the proven diagnostic of adenocarcinoma were admitted for surgical treatment at the gastric cancer specialized ward of Rebagliati National Hospital, Lima, Peru. RESULTS: Female was more frequent in diffuse type (39 percent vs. 33 percent; p: 0,153), the mean age among intestinal type is greater than diffuse type (70,7 vs. 62,6 años; p<0,001). There is association among poorly differentiated with upper location (22 percent vs. 12,7 percent; p = 0,009), signet cell with middle location (50 percent vs. 32,5 percent; p: 0,006), tubular type with distal location (57,6 percent vs. 42,8 percent; p: 0,002), intestinal type with distal location (58,3 percent vs. 44,1 percent; p: 0,004), and diffuse type with upper location (19,3 percent vs. 12,5 percent; p: 0,049). CONCLUSION: Adenocarcinomas histologically differentiated or intestinal type are associated with distal location. Poorly differentiated type and signet ring cell type are associated with upper and middle location respectively.
Assuntos
Humanos , Masculino , Adulto , Feminino , Pessoa de Meia-Idade , Idoso de 80 Anos ou mais , Adenocarcinoma , Neoplasias Gástricas/secundárioRESUMO
This report describes the case of a patient who underwent total gastrectomy, splenectomy and pancreatomy corporo-postero as a consequence of gastric and pancreatic metastasis from carcinoma to clear cells, five years after having undergone radical nephrectomy. Upper digestive bleeding was the first symptom, and pancreatic lesion was detected in previous CT scans. There are many documented cases of pancreatic metastasis, but only eight gastric metastasis in the last 15 years, although we did not find reports about surgical treatment for concomitant gastric and pancreatic injury. Surgical treatment which in some reports include highly complex surgeries such as gastrectomies with combined resections of invaded organs and pancreatoduodenectomy, are good options for select cases, because good survival rates have been reported.
Assuntos
Carcinoma de Células Renais/secundário , Neoplasias Renais/patologia , Neoplasias Pancreáticas/secundário , Neoplasias Gástricas/secundário , Idoso , Carcinoma de Células Renais/cirurgia , Feminino , Humanos , Neoplasias Renais/cirurgia , Neoplasias Pancreáticas/cirurgia , Neoplasias Gástricas/cirurgiaRESUMO
El presente reporte describe las características del cáncer gástrico temprano sometido a tratamiento quirúrgico en el Servicio de Cirugía de Estómago del Hospital Nacional Rebagliati en el quinquenio comprendido entre enero del 2004 y diciembre del 2008. La edad promedio fue de 68 años; predomina el sexo masculino, la localización distal, la infiltración a submucosa y el tipo histológico intestinal. La metástasis ganglionar se presenta en el 13%.
This report describes the characteristics of early gastric cancer surgically treated in the Gastric Cancer Unit at Rebagliati National Hospital between January 2004 and December 2008. Mean age was 68 years; males, distal location, submucosa infiltration and intestinal histological type predominate in these patients. Lymph node involvement was 13%.
Assuntos
Humanos , Masculino , Feminino , Idoso , Endoscopia do Sistema Digestório , Neoplasias Gástricas/cirurgiaRESUMO
The results of the surgical treatment for gastric cancer within a specialized surgical service in this pathology are described in this work. This system for surgical treatment of gastric cancer is new in our country. The implementation process included prepare a team of surgeons and establish protocols and guides to surgical treatment, based on the recommendations of the Japanese Gastric Cancer Association. Additional training in the Japanese advanced surgical technique was required, as well as a strict documentation of the cases. During 2004, 139 surgical interventions were carried out on 137 patients with tumoral gastric pathology. Surgical mortality was 2.1% and morbidity was 21.8%. The average resected glands was 38.6.t 13.7 (range: 20-87) for distal gastrectomy and 46.6 +/- 16.2 (range: 24-87) for total gastrectomy. The stay in the hospital was 11.7 +/- 6.3 days (range: 5-37) for distal gastrectomy and 14.8 +/- 11.3 days (range: 7-56) for total gastrectomy. The hospital and surgeon volumes are underlined as important factors in determining the short and long term results. Implementation of specialized surgical units in general hospitals, for surgical treatment of gastric cancer, is recommended.
Assuntos
Adenocarcinoma/cirurgia , Gastrectomia , Neoplasias Gástricas/cirurgia , Adenocarcinoma/mortalidade , Idoso , Institutos de Câncer , Europa (Continente) , Mortalidade Hospitalar , Humanos , Japão , Tempo de Internação , Excisão de Linfonodo , Peru , Complicações Pós-Operatórias , Estudos Prospectivos , Ensaios Clínicos Controlados Aleatórios como Assunto , Neoplasias Gástricas/mortalidade , Centro Cirúrgico HospitalarRESUMO
La disección submucosa por vía endoscópica es un método de tratamiento novedoso, difundido básicamente para el manejo del cáncer gástrico temprano, aunque también constituye una buena elección para lesiones benignas de regular tamaño si es que se quiere lograr una resección en "una pieza". Sin embargo para su realización se necesita no sólo gastroenterólogos entrenados y experimentados en dicha técnica sino también la utilización de instrumental apropiado que no necesariamente se encuentra disponible en nuestro país. El presente trabajo describe el caso de una paciente portadora de un pólipo hiperplásico de tercio superior de estómago que se que por sus dimensiones y características fue sometida a tratamiento quirúrgico a través de una disección submucosa a cielo abierto y es a nuestro entender el primer caso descrito en la literatura médica en que se emplea esta técnica en una cirugía a cielo abierto.
Endoscopic submucosal dissection is a new treatment, basically for the management of early gastric cancer, it is also a good option for large benign lesions if a "una pieza" resection needs to be performed. However this technique requires not only gastroenterologist with proven technical skill, but also some special devices not necessarily disposables in our country. The present paper describes the case of a patient with a large hyperplastic polyp located in the upper third of the stomach who underwent an open endoscopic submucosal dissection to resect the lesion owing to its size and characteristics. According our knowledge this is the first case in the medical literature describing the use of this technique during an open surgery.
Assuntos
Humanos , Idoso , Feminino , Dissecação , PóliposRESUMO
La gastrectomía con linfadenectomía D2 es la cirugía estándar en la mayoría de centros hospitalarios del Perú debido a que la técnica quirúrgica japonesa ha mostrado los mejores resultados en todo el mundo. Sin embargo nunca se ha realizado un estudio comparando los resultados de linfadenectomía D2 con D1 en nuestro país. El presente estudio de tipo cohorte retrospectivo compara la linfadenectomia D2 versus D1 en el tratamiento quirúrgico del cáncer gástrico. 316 pacientes fueron sometidos a cirugía por cáncer gástrico entre Enero del 2000 y Diciembre del 2002 en el Hospital Nacional Rebagliati y se seleccionaron en forma aleatoria un total de 100 pacientes, 50 de ellos fueron sometidos a linfadenectomía D1 y otros 50 a linfadenectomía D2 respectivamente. La mortalidad fue de 8 por ciento para D1 y 4 por ciento para D2 (p:NS), mientras que la morbilidad fue de 24 por ciento para D1 y 12 por ciento para D2 (p:NS). La sobrevida a 3 años fue de 36 por ciento para D1 y 56 por ciento para D2 estableciendo una diferencia estadísticamente significativa (p:0.04). Se recomienda la gastrectomía con linfadenectomía D2 como tratamiento quirúrgico de elección para el cáncer gástrico avanzado.
Gastrectomy with D2 lymphadenectomy is the standard surgical procedure in most hospitals in Peru due to the fact that this Japanese surgical technique has proven to provide the best results in the world. However, no comparative study of the results of D1 and D2 lymphadenectomies has ever been performed in our country. This retrospective cohort study compares D2 lymphadenectomy versus D1 in surgicaltreatment of gastric cancer. Between January 2000 and December 2002, 316 patients underwent surgery at the Rebagliati National Hospital and a total of 100 patients were randomly selected, 50 of which underwent a D1 lymphadenectomy and 50 a D2 lymphadenectomy. Mortality rates were 8 per cent for D1 lymphadenectomy and 4 per cent for D2, whereas morbidityrates were 24 per cent for D1 and 12 per cent for D2. Survival after 3 years was 36 per cent for D1 and 56 per centfor D2 thus establishing a statistically significant difference (p = 0.04). We recommend gastrectomy with D2 lymphadenectomy as the surgical treatment of choice for advanced gastric cancer.
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Feminino , Excisão de Linfonodo , Gastrectomia , Neoplasias Gástricas/cirurgia , Sobrevida , Estudos Retrospectivos , Estudos de CoortesRESUMO
El presente reporte se describe el caso de una paciente sometida a gastrectomía total, esplenectomía y pancreatectomía corporo-caudal por presentar metástasis gástrica y pancreática de carcinoma renal a células claras, 5 años después de haber sido sometida a nefrectomía radical. El cuadro se presentó como una hemorragia digestiva alta, y la lesión pancreática se evidenció en los estudios tomográficos previos a los que fue sometida la paciente. Existen muchos casos reportados en la literatura de metástasis pancreática, pero solo 8 en relación a metástasis gástrica. Sin embargo no encontramos reportado el tratamiento quirúrgico por lesión gástrica y pancreática concomitante. El tratamiento quirúrgico que en algunos reportes incluye cirugías de alta complejidad como gastrectomías con resecciones combinadas de otros órganos y pancreatoduodenectomía, se ofrecen como una buena alternativa para casos seleccionados ya que se han reportado buenas sobrevidas.
This report describes the case of a patient who underwent total gastrectomy,splenectomy and pancreatomy corporo-postero as a consequence of gastric and pancreatic metastasis from carcinoma to clear cells, five years after having undergoneradical nephrectomy. Upper digestive bleeding was the first symptom, and pancreatic lesion was detected in previous CT scans. There are many documented cases of pancreatic metastasis, but only eight gastric metastasis in the last 15 years, althoughwe did not find reports about surgical treatment for concomitant gastric and pancreatic injury. Surgical treatment which in so me reports include highly complex surgeries such as gastrectomies with combined resections of invaded organs andpancreato duodenectomy, are good options for select cases, because good survivalrates have been reported.