Detalhe da pesquisa
1.
Hypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells.
Proc Natl Acad Sci U S A
; 112(14): 4441-6, 2015 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25792458
2.
TBC1D16 is a Rab4A GTPase activating protein that regulates receptor recycling and EGF receptor signaling.
Proc Natl Acad Sci U S A
; 109(39): 15787-92, 2012 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23019362
3.
The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation.
Cancer Cell
; 8(6): 443-54, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16338658
4.
Notch1 is an effector of Akt and hypoxia in melanoma development.
J Clin Invest
; 118(11): 3660-70, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18924608
5.
Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras mice.
Cancer Res
; 66(6): 2946-52, 2006 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16540642
6.
Targeting integrins and PI3K/Akt-mediated signal transduction pathways enhances radiation-induced anti-angiogenesis.
Radiat Res
; 168(1): 125-33, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17722999
7.
Inhibition of phosphatidylinositol-3-kinase and mitogen-activated protein kinase kinase 1/2 prevents melanoma development and promotes melanoma regression in the transgenic TPRas mouse model.
Mol Cancer Ther
; 5(12): 3071-7, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17172409
8.
Topical treatment with inhibitors of the phosphatidylinositol 3'-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways reduces melanoma development in severe combined immunodeficient mice.
Cancer Res
; 64(7): 2552-60, 2004 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15059911
9.
Effects of perillyl alcohol on melanoma in the TPras mouse model.
Cancer Epidemiol Biomarkers Prev
; 11(6): 573-9, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12050099
10.
Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers.
Arch Dermatol
; 140(7): 827-35, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15262693
11.
Neonatal ultraviolet radiation exposure is critical for malignant melanoma induction in pigmented Tpras transgenic mice.
J Invest Dermatol
; 125(5): 1074-7, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16297212
12.
Hypoxia, melanocytes and melanoma - survival and tumor development in the permissive microenvironment of the skin.
Pigment Cell Melanoma Res
; 22(2): 166-74, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19222803
13.
Skin hypoxia: a promoting environmental factor in melanomagenesis.
Cell Cycle
; 5(12): 1258-61, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16760649
14.
Melanocyte and keratinocyte carcinogenesis: p53 family protein activities and intersecting mRNA expression profiles.
J Investig Dermatol Symp Proc
; 10(2): 142-52, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16363065
15.
Unique transforming properties of Notch1 in human melanocytes.
Pigment Cell Melanoma Res
; 22(6): 702-3, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19708913