Detalhe da pesquisa
1.
Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency.
Nat Immunol
; 25(5): 764-777, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38609546
2.
Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children.
Nat Immunol
; 24(1): 186-199, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36536106
3.
Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity.
Nat Immunol
; 19(9): 986-1000, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30127432
4.
"Stripe" transcription factors provide accessibility to co-binding partners in mammalian genomes.
Mol Cell
; 82(18): 3398-3411.e11, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35863348
5.
PI3Kγδ inhibition suppresses key disease features in a rat model of asthma.
Respir Res
; 25(1): 175, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38654248
6.
Common genetic susceptibility loci link PFAPA syndrome, Behçet's disease, and recurrent aphthous stomatitis.
Proc Natl Acad Sci U S A
; 117(25): 14405-14411, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32518111
7.
T and B-cell signaling in activated PI3K delta syndrome: From immunodeficiency to autoimmunity.
Immunol Rev
; 291(1): 154-173, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31402502
8.
Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype.
Immunity
; 38(3): 596-605, 2013 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23499493
9.
Cytokine-regulated Th17 plasticity in human health and diseases.
Immunology
; 163(1): 3-18, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33064842
10.
Antibody-driven design of a human cytomegalovirus gHgLpUL128L subunit vaccine that selectively elicits potent neutralizing antibodies.
Proc Natl Acad Sci U S A
; 111(50): 17965-70, 2014 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25453106
11.
Somatic mutations and affinity maturation are impaired by excessive numbers of T follicular helper cells and restored by Treg cells or memory T cells.
Eur J Immunol
; 45(11): 3010-21, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26332258
12.
In vivo CRISPR screens reveal a HIF-1α-mTOR-network regulates T follicular helper versus Th1 cells.
Nat Commun
; 13(1): 805, 2022 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35145086
13.
A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells.
Sci Signal
; 15(743): eabl9169, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35857633
14.
Robust, persistent adaptive immune responses to SARS-CoV-2 in the oropharyngeal lymphoid tissue of children.
Res Sq
; 2022 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35350206
15.
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell Rep
; 37(2): 109804, 2021 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34644563
16.
Genetic Defects in Phosphoinositide 3-Kinase δ Influence CD8+ T Cell Survival, Differentiation, and Function.
Front Immunol
; 9: 1758, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30116245
17.
PI3K Orchestrates T Follicular Helper Cell Differentiation in a Context Dependent Manner: Implications for Autoimmunity.
Front Immunol
; 9: 3079, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30666254
18.
Special Focus Issue on Emerging Scientists and Science Communication.
DNA Cell Biol
; 41(1): 1-2, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34964672
19.
Experimental priming of encephalitogenic Th1/Th17 cells requires pertussis toxin-driven IL-1ß production by myeloid cells.
Nat Commun
; 7: 11541, 2016 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27189410
20.
CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development.
PLoS One
; 11(6): e0156072, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27258160