Primacy (and recency) effects in delayed recognition of items from instances of repeated events.

In repeated-event paradigms where participants are asked to recall details of a sequence of similar instances they viewed/experienced previously, more accurate details are typically recalled from the first and final instances (i.e., long-term primacy and recency effects). Participants likely encode distinct attributes of details of the boundary instances that subsequently facilitate source monitoring. To date, most repeated event research has measured memory performance via free-/cued-recall paradigms; we examined delayed memory for repeated events using the recognition paradigm. In two preregistered experiments, participants viewed four videos, and after a delay completed a recognition task. In Experiment 1 (N = 168, between-subjects), participants decided whether an item was old (i.e., presented in any video) or new, or whether an item was presented in video 1/2/3/4 or was new. In Experiment 2 (N = 160, within-subjects), the old/new decision was followed by an instance attribution decision. Old items were recognised faster in the old/new task compared to the instance-attribution task. In the instance-attribution task, items from the boundary instances were accurately attributed faster compared to items from the middle instances. We found further evidence for primacy (and recency) effects in measures of confidence, memory judgments, recognition accuracy and discriminability, and confidence-accuracy calibration.

Asthma symptoms, spirometry and air pollution exposure in schoolchildren in an informal settlement and an affluent area of Nairobi, Kenya.

BACKGROUND: Although 1 billion people live in informal (slum) settlements, the consequences for respiratory health of living in these settlements remain largely unknown. This study investigated whether children living in an informal settlement in Nairobi, Kenya are at increased risk of asthma symptoms. METHODS: Children attending schools in Mukuru (an informal settlement in Nairobi) and a more affluent area (Buruburu) were compared. Questionnaires quantified respiratory symptoms and environmental exposures; spirometry was performed; personal exposure to particulate matter (PM2.5) was estimated. RESULTS: 2373 children participated, 1277 in Mukuru (median age, IQR 11, 9-13 years, 53% girls), and 1096 in Buruburu (10, 8-12 years, 52% girls). Mukuru schoolchildren were from less affluent homes, had greater exposure to pollution sources and PM2.5. When compared with Buruburu schoolchildren, Mukuru schoolchildren had a greater prevalence of symptoms, 'current wheeze' (9.5% vs 6.4%, p=0.007) and 'trouble breathing' (16.3% vs 12.6%, p=0.01), and these symptoms were more severe and problematic. Diagnosed asthma was more common in Buruburu (2.8% vs 1.2%, p=0.004). Spirometry did not differ between Mukuru and Buruburu. Regardless of community, significant adverse associations were observed with self-reported exposure to 'vapours, dusts, gases, fumes', mosquito coil burning, adult smoker(s) in the home, refuse burning near homes and residential proximity to roads. CONCLUSION: Children living in informal settlements are more likely to develop wheezing symptoms consistent with asthma that are more severe but less likely to be diagnosed as asthma. Self-reported but not objectively measured air pollution exposure was associated with increased risk of asthma symptoms.

Categorizing Complainant-Accused Relationships in Cases of Child Sexual Abuse: The Distinctive Nature of Community Connections.

We examined the categorization of relationships between child complainants and accused perpetrators in cases of child sexual abuse (CSA). Researchers that have focused on complainant-accused relationships and other case variables, often combining two extrafamilial complainant-accused relationship categories: Relationships where the accused is connected to the child through their position in the community (i.e. community connections) and relationships where the non-relative accused is known to the child through a connection to the child's family (i.e. non-relative family connections). Using a database of 4,237 Canadian judicial decisions in cases of CSA, we reviewed a subset of 1,515 judicial decisions to explore differences between these two relationship categories. Compared to cases involving non-relative family connections, cases involving community connections had more male complainants, more multiple complainants, older complainants, higher frequencies of abuse, longer durations, and longer delays. We conclude that community and non-relative family connections are distinct relationships that should be separated for analyses in future research. Practical implications of recognizing the distinctiveness of non-relative family and community connection relationship categories in the context of abuse prevention and treatment are also discussed.

The impact of COVID-19 on Canadian child maltreatment workers.

As cases of child maltreatment become an increasing concern during the COVID-19 pandemic, the perspectives of those charged with protecting and supporting children and families is an important area of inquiry. We sought to examine the experiences of child maltreatment workers during the first wave of the pandemic (i.e., May-July 2020). We specifically aimed to examine child maltreatment experiences related to the following: (1) their work practices during the pandemic, (2) their perceived safety during the pandemic, and (3) their perceptions on the safety of the children and families with whom they work. A total of 106 child maltreatment investigators and forensic interviewers provided responses to a national survey disseminated across Canada. Using a cross-sectional design, data were collected through a survey management program. The survey combined both open-ended and forced choice questions to gather perspectives on respondents' experiences. More than half (67%) reported a reduction in their caseloads during the pandemic (May-July 2020) and continued in-person interviews, with the use of preventative health measures (i.e., PPE, physical distancing, gloves). Most respondents reported elevated stress levels and similarly high stress levels amongst the children and families to whom they provide services. Overall, our findings highlight both how child maltreatment investigators have adapted to preventative measures and the continuing areas of weakness where further supports are required.

Perceptions of familiar and unfamiliar ear- and eyewitnesses.

A witness's relationship with a defendant is frequently discussed in criminal trials, yet investigations into perceptions of this relationship have been scarce. Further, an exploration of witnesses other than eyewitnesses has been missing from the literature. The present studies explored how witness type and familiarity with a defendant impact the perceived credibility of a witness. In Study 1, a familiar earwitness was perceived as more credible and honest than a stranger earwitness but the same was not found for eyewitnesses. Results from Study 2 suggest an eyewitness was seen as more credible and believable than an earwitness, and that a familiar witness was seen as more reliable than a stranger, but not than an acquaintance. There was no impact of familiarity or witness type on legal decisions. The present studies indicate that the prior definitions of familiarity might only capture a restricted range of potentially familiar relations.

How Do Judges Discuss Memory Failures in Childhood Sexual Abuse Cases? A Brief Report.

The natural fading of memory presents a difficulty for complainants who report childhood sexual abuse after a significant delay. The complainant's recollections, and their failures to recollect, may be the only source of evidence about the alleged offense and so may be determinative of outcome. We analyzed 101 published judicial decisions of timely tried and delayed complaints of child sexual abuse and coded for judge's comments related to complainants' memory failures. We utilized qualitative and quantitative methods for this study. There were more memory failure comments reported for cases with a delay to trial compared to no delay to trial. Further, there were more memory failure comments in cases that ended in acquittals than convictions when there was a delay to trial. Judicial discussion of memory failures about abuse setting or circumstances accounted for the highest percentage of comments.

Using machine learning analyses to explore relations between eyewitness lineup looking behaviors and suspect guilt.

OBJECTIVE: We conducted 2 experiments using machine learning to better understand which lineup looking behaviors postdict suspect guilt., Hypotheses: We hypothesized that (a) lineups with guilty suspects would be subject to shorter viewing duration of all images and fewer image looks overall than lineups with innocent suspects, and (b) confidence and accuracy would be positively correlated. The question of which factors would combine to best postdict suspect guilt was exploratory. METHOD: Experiment 1 included 405 children (6-14 years; 43% female) who each made 2 eyewitness identifications after viewing 2 live targets. Experiment 2 included 342 adult participants (Mage = 21.00; females = 75%) who each made 2 identifications after viewing a video including 2 targets. Participants made identifications using an interactive touchscreen simultaneous lineup in which they were restricted to viewing one image at a time and their interaction with the lineup was recorded. RESULTS: In Experiment 1, five variables (filler look time, suspect look time, number of suspect looks, number of filler looks, and winner look time) together postdicted (with a 67% accuracy score) target presence. In Experiment 2, four variables (number of suspect looks, number of filler looks, number of loser looks, and winner looks) together postdicted (with a 73% accuracy score) target presence. CONCLUSIONS: Further exploration of witness search behaviors can provide context to identification decisions. Understanding which behaviors postdict suspect guilt may assist with interpretation of identification decisions in the same way that decision confidence is currently used. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

A meta-analysis of differences in children's reports of single and repeated events.

When children report abuse, they often report that it occurred repeatedly. In most jurisdictions, children will be asked to report each instance of abuse with as many details as possible. In the current meta-analysis, we analyzed data from 31 experiments and 3099 children. When accuracy was defined as the number of correct details from the target instance (i.e., narrow definition), repeated-event children were less accurate than single-event children. However, we argue that defining accuracy as the number of reported details that were experienced across instances (i.e., broad definition) is more appropriate for repeated events. When a broad definition was applied, single- and repeated-event children were similarly accurate. Importantly, repeated-event children were less likely than single-event children to report details that had never been experienced and they were no more likely to say "I don't know." Overall, repeated-event children were more suggestible than single-event children, but this was moderated by length of delay to recall. In analyses of recognition data, single-event children's sensitivity score was higher than repeated-event children's, with no significant difference in response bias as a function of event frequency. We discuss these results in the context of how children's memory for repeated events is organized. We also consider the advantage of applying a broad definition of accuracy for victims of repeated abuse and charging repeated abuse as a continuous offense rather than discrete acts. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Boys Abused in a Community Setting: An Analysis of Gender, Relationship, and Delayed Prosecutions in Cases of Child Sexual Abuse.

Previous research on gender differences and delay of disclosure of child sexual abuse is inconclusive; some research has found that male victims are more likely to delay disclosure than female victims, while other studies have found no gender difference. The present archival study investigated this inconsistency by examining factors that interact with delay. Judicial outcomes of child sexual abuse cases were coded (N = 4237) for variables related to the offense, the complainant-accused relationship, and court proceedings. Males and females differed with respect to delay only when the relationship between the complainant and the accused was established in the community (e.g., sports coach) or was a stranger to the child. When the accused was a parent, other relative, or a non-relative connected to the child through the family, there was no difference in delay between males and females. Further, males were more vulnerable in the community, as evidenced by a higher proportion of accused community members with male than female complainants, even though males represented fewer than 25% of cases in the database. These findings may help explain inconsistencies in gender differences in delayed disclosure. Implications regarding education about child sexual abuse are discussed, with a focus on male victims.

Eyewitness Identification: Live, Photo, and Video Lineups.

The medium used to present lineup members for eyewitness identification varies according to the location of the criminal investigation. Although in some jurisdictions live lineups remain the default procedure, elsewhere this practice has been replaced with photo or video lineups. This divergence leads to two possibilities: Either some jurisdictions are not using the lineup medium that best facilitates accurate eyewitness identification or the lineup medium has no bearing on the accuracy of eyewitness identification. Photo and video lineups are the more practical options, but proponents of live lineups believe witnesses make better identification decisions when the lineup members are physically present. Here, the authors argue against this live superiority hypothesis. To be superior in practice, the benefits of live presentation would have to be substantial enough to overcome the inherent difficulties of organizing and administering a live lineup. The review of the literature suggests that even in experimental settings, where these difficulties can be minimized, it is not clear that live lineups are superior. The authors conclude that live lineups are rarely the best option in practice and encourage further research to establish which nonlive medium provides the best balance between probative value and practical utility.

Investigator Sensitivity to Alibi Witness Inconsistency after a Long Delay.

In two studies, mock investigators conducted a computer-based investigation of a crime involving an alibi witness who varied in the consistency of his statements taken 5 years apart. Investigators showed evidence of skepticism of alibi witness statements in which major contradictions (activity, location) were present, and some skepticism of statements in which minor (activity) details were contradictory. Entirely consistent statements were judged favorably, and reduced perceptions of suspect guilt (Study 2). The age of the alibi witness did not impact judgments of suspect guilt when children (6 years) and adults (25 years) were compared (Study 1, N = 254), or when children of different ages were compared (6, 8, 11 years; Study 2, N = 234). The present data suggest that investigators were relatively more sensitive to considerations of accuracy than honesty. Copyright © 2017 John Wiley & Sons, Ltd.

How sure are you that this is the man you saw? Child witnesses can use confidence judgments to identify a target.

We tested whether an alternative lineup procedure designed to minimize problematic influences (e.g., metacognitive development) on decision criteria could be effectively used by children and improve child eyewitness identification performance relative to a standard identification task. Five hundred sixteen children (6- to 13-year-olds) watched a video of a target reading word lists and, the next day, made confidence ratings for each lineup member or standard categorical decisions for 8 lineup members presented sequentially. Two algorithms were applied to classify confidence ratings into categorical decisions and facilitate comparisons across conditions. The classification algorithms produced accuracy rates for the confidence rating procedure that were comparable to the categorical procedure. These findings demonstrate that children can use a ratings-based procedure to discriminate between previously seen and unseen faces. In turn, this invites more nuanced and empirical consideration of ratings-based identification evidence as a probabilistic index of guilt that may attenuate problematic social influences on child witnesses' decision criteria. (PsycINFO Database Record

Assessment of Urine Proteomics in Type 1 Primary Hyperoxaluria.

BACKGROUND: Primary hyperoxaluria type 1 (PH1) and idiopathic hypercalciuria (IHC) are stone-forming diseases that may result in the formation of calcium (Ca) oxalate (Ox) stones, nephrocalcinosis, and progressive chronic kidney disease (CKD). Poorer clinical outcome in PH1 is segregated by the highest urine (Ur)-Ox (UrOx), while IHC outcomes are not predictable by UrCa. We hypothesized that differences would be found in selected Ur-protein (PRO) patterns in PH1 and IHC, compared to healthy intra-familial sibling controls (C) of PH1 patients. We also hypothesized that the PRO patterns associated with higher UrOx levels would reflect injury, inflammation, biomineralization, and abnormal tissue repair processes in PH1. METHODS: Twenty four-hour Ur samples were obtained from 3 cohorts: PH1 (n = 47); IHC (n = 35) and C (n = 13) and were analyzed using targeted platform-based multi-analyte profile immunoassays and for UrOx and UrCa by biochemical measurements. RESULTS: Known stone matrix constituents, osteopontin, calbindin, and vitronectin were lowest in PH1 (C > IHC > PH1; p < 0.05). Ur-interleukin-10; chromogranin A; epidermal growth factor (EGF); insulin-like growth factor-1 (IGF-1), and macrophage inflammatory PRO-1α (MIP-1α) were higher in PH1 > C (p = 0.03 to p < 0.05). Fetuin A; IGF-1, MIP-1α, and vascular cell adhesion molecule-1 were highest in PH1 > IHC (p < 0.001 to p = 0.005). CONCLUSION: PH1 Ur-PROs reflected overt inflammation, chemotaxis, oxidative stress, growth factors (including EGF), and pro-angiogenic and calcification regulation/inhibition compared to the C and IHC cohorts. Many of the up- and downregulated PH1-PROs found in this study are also found in CKD, acute kidney injury, stone formers, and/or stone matrices. Further data analyses may provide evidence for PH1 unique PROs or demonstrate a poorer clinical outcome.

Children who experienced a repeated event only appear less accurate in a second interview than those who experienced a unique event.

When children have experienced a repeated event, reports of experienced details may be inconsistently reported across multiple interviews. In 3 experiments, we explored consistency of children's reports of an instance of a repeated event after a long delay (Exp. 1, N = 53, Mage = 7.95 years; Exp. 2, N = 70, Mage = 5.77 years, Exp. 3, N = 59, Mage = 4.88 years). In all experiments, children either experienced 1 or 4 activity sessions, followed at a relatively short delay (days or weeks) by an initial memory test. Then, following a longer delay (4 months or 1 year), children were reinterviewed with the same memory questions. We analyzed the consistency of children's memory reports across the 2 interviews, as well as forgetting, reminiscence, and accuracy, defined with both narrow and broad criteria. A highly consistent pattern was observed across the 3 experiments with children who experienced a single event appearing more consistent than children who experienced a repeated event. We conclude that inconsistencies across multiple interviews can be expected from children who have experienced repeated events and these inconsistencies are often reflective of accurate, but different, recall. (PsycINFO Database Record

True (but not false) memories are subject to retrieval-induced forgetting in children.

Veridical and false memories of children aged 6 to 15 years were studied in two experiments with the retrieval-induced forgetting paradigm. Using the Deese-Roediger-McDermott (DRM) false memory word lists, children's reports of true, but not false, memories showed evidence of retrieval-induced forgetting. These differences were observed across delays as long as 2 days following word list presentation. The lack of observation of retrieval-induced forgetting in children's false memories provides evidence that a key assumption in the theory of retrieval-induced forgetting, cue independence, might not consistently apply. These experiments underscore the need for both practical and theoretically motivated study of true and false memories.

Suspect filler similarity in eyewitness lineups: a literature review and a novel methodology.

Eyewitness lineups typically contain a suspect (guilty or innocent) and fillers (known innocents). The degree to which fillers should resemble the suspect is a complex issue that has yet to be resolved. Previously, researchers have voiced concern that eyewitnesses would be unable to identify their target from a lineup containing highly similar fillers; however, our literature review suggests highly similar fillers have only rarely been shown to have this effect. To further examine the effect of highly similar fillers on lineup responses, we used morphing software to create fillers of moderately high and very high similarity to the suspect. When the culprit was in the lineup, a higher correct identification rate was observed in moderately high similarity lineups than in very high similarity lineups. When the culprit was absent, similarity did not yield a significant effect on innocent suspect misidentification rates. However, the correct rejection rate in the moderately high similarity lineup was 20% higher than in the very high similarity lineup. When choosing rates were controlled by calculating identification probabilities for only those who made a selection from the lineup, culprit identification rates as well as innocent suspect misidentification rates were significantly higher in the moderately high similarity lineup than in the very high similarity lineup. Thus, very high similarity fillers yielded costs and benefits. Although our research suggests that selecting the most similar fillers available may adversely affect correct identification rates, we recommend additional research using fillers obtained from police databases to corroborate our findings.

Fibroblast growth factor-23 in obese, normotensive adolescents is associated with adverse cardiac structure.

OBJECTIVES: Fibroblast growth factor-23 (FGF23) is a biomarker for cardiovascular disease. Obesity may promote FGF23 production in the absence of chronic kidney disease. We sought to determine among normotensive African American adolescents whether FGF23 levels are greater in obese compared with normal-weight adolescents and to determine the relationship of FGF23 with markers of cardiac structure and insulin resistance. STUDY DESIGN: Cross-sectional data were obtained from a cohort of 130 normotensive, African American adolescents ages 13-18 years without chronic kidney disease; 74 were obese; 56 were normal weight. Plasma C-terminal FGF23, fasting glucose and insulin, and high-sensitivity C-reactive protein were measured; participants underwent M-mode echocardiography. RESULTS: FGF23 was skewed and approximately normally distributed after natural log transformation (logFGF23). FGF23 levels were greater in obese vs normal-weight participants (geometric mean 43 vs 23 RU/mL, P < .01). FGF23 values were significantly greater in participants with eccentric or concentric cardiac hypertrophy compared with those without hypertrophy P < .01). LogFGF23 directly correlated with body mass index, body mass index z-score, waist circumference, fasting insulin levels, and homeostasis model assessment scores. Regression models adjusted for age, sex, and high-sensitivity C-reactive protein suggest that each 10% increase in FGF23 is associated with a 1.31 unit increase in left ventricular mass (P < .01), a 0.29-unit increase in left ventricular mass index (P < .01), and a 0.01-unit increase in left atrial dimension indexed to height (P = .02). CONCLUSIONS: In this sample of obese African American adolescents, FGF23 blood levels were associated with abnormal cardiac structure. We postulate that FGF23 may be an early marker of cardiac injury in obese but otherwise-healthy African American adolescents.

Hyperphosphatemic familial tumoral calcinosis: response to acetazolamide and postulated mechanisms.

Hyperphosphatemic familial tumoral calcinosis (HFTC) is characterized by enhanced renal phosphate absorption, hyperphosphatemia, and tumor-like extraosseous calcifications due to inactivating mutations in FGF23 or associated proteins. Surgical excision is needed when low phosphate diet and phosphate binders are ineffective. Sporadic reports have supported acetazolamide use. We report on a 7-year-old African American boy who presented with severe HFTC requiring numerous surgical excisions. Tumors continued to appear and others reoccurred despite phosphate restriction and sevelamer carbonate. At the age of 9.5 years, acetazolamide (40 mg/kg/day) was added and resulted in mild metabolic acidosis (bicarbonate 25.3 mEq/L vs. 21.4 mEq/L, P < 0.001; serum pH 7.38 vs. 7.31, P = 0.013, pre- and post-acetazolamide, respectively) but no change in tubular reabsorption of phosphate (TRP) (96.9% vs. 95.9%, P = 0.34) or serum phosphate (6.6 mg/dl vs. 6.9 mg/dl, P = 0.52 pre- and post-acetazolamide, respectively). Following the initiation of acetazolamide therapy, the patient experienced significant improvement in disease course as indicated by resolution of localized bone pain, cessation of tumor formation, and no tumor recurrence. Despite mild metabolic acidosis, our patient had improved linear growth and did not develop any other side effects related to therapy. Intact FGF23 remained abnormally low throughout disease course, while C-terminal FGF23 increased with acetazolamide. We conclude that acetazolamide can control severe HFTC by inducing mild metabolic acidosis despite no change in serum phosphate or TRP. This effect may be exerted though improved calcium-phosphate complex solubility and increased FGF23 locally.

"I have to stay inside ": Experiences of air pollution for people with asthma.

Asthma, characterized by airway inflammation, sensitization and constriction, and leading to symptoms including cough and dyspnoea, affects millions of people globally. Air pollution is a known asthma trigger, yet how it is experienced is understudied and how individuals with asthma interact with air quality information and manage exacerbation risks is unclear. This study aimed to explore how people living with asthma in Scotland, UK, experienced and managed their asthma in relation to air pollution. We explored these issues with 36 participants using semi-structured interviews. We found that self-protection measures were influenced by place and sense of control (with the home being a "safe space"), and that the perception of clean(er) air had a liberating effect on outdoor activities. We discuss how these insights could shape air quality-related health advice in future.

Piloting co-developed behaviour change interventions to reduce exposure to air pollution and improve self-reported asthma-related health.

BACKGROUND: Exposure to air pollution can exacerbate asthma with immediate and long-term health consequences. Behaviour changes can reduce exposure to air pollution, yet its 'invisible' nature often leaves individuals unaware of their exposure, complicating the identification of appropriate behaviour modifications. Moreover, making health behaviour changes can be challenging, necessitating additional support from healthcare professionals. OBJECTIVE: This pilot study used personal exposure monitoring, data feedback, and co-developed behaviour change interventions with individuals with asthma, with the goal of reducing personal exposure to PM2.5 and subsequently improving asthma-related health. METHODS: Twenty-eight participants conducted baseline exposure monitoring for one-week, simultaneously keeping asthma symptom and medication diaries (previously published in McCarron et al., 2023). Participants were then randomised into control (n = 8) or intervention (n = 9) groups. Intervention participants received PM2.5 exposure feedback and worked with researchers to co-develop behaviour change interventions based on a health behaviour change programme which they implemented during the follow-up monitoring week. Control group participants received no feedback or intervention during the study. RESULTS: All interventions focused on the home environment. Intervention group participants reduced their at-home exposure by an average of 5.7 µg/m³ over the monitoring week (-23.0 to +3.2 µg/m³), whereas the control group had a reduction of 4.7 µg/m³ (-15.6 to +0.4 µg/m³). Furthermore, intervention group participants experienced a 4.6% decrease in participant-hours with reported asthma symptoms, while the control group saw a 0.5% increase. Similarly, the intervention group's asthma-related quality of life improved compared to the control group. IMPACT STATEMENT: This pilot study investigated a novel behaviour change intervention, utilising personal exposure monitoring, data feedback, and co-developed interventions guided by a health behaviour change programme. The study aimed to reduce personal exposure to fine particulate matter (PM2.5) and improve self-reported asthma-related health. Conducting a randomised controlled trial with 28 participants, co-developed intervention successfully targeted exposure peaks within participants' home microenvironments, resulting in a reduction in at-home personal exposure to PM2.5 and improving self-reported asthma-related health. The study contributes valuable insights into the environmental exposure-health relationship and highlights the potential of the intervention for individual-level decision-making to protect human health.