Detalhe da pesquisa
1.
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
J Allergy Clin Immunol
; 133(6): 1564-71, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24388013
2.
Heterocyclic methylsulfone hydroxamic acid LpxC inhibitors as Gram-negative antibacterial agents.
Bioorg Med Chem Lett
; 22(22): 6832-8, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23046961
3.
Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors.
J Med Chem
; 58(7): 3223-52, 2015 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25781223
4.
A novel morpholino oligomer targeting ISS-N1 improves rescue of severe spinal muscular atrophy transgenic mice.
Hum Gene Ther
; 24(3): 331-42, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23339722
5.
Improved antisense oligonucleotide design to suppress aberrant SMN2 gene transcript processing: towards a treatment for spinal muscular atrophy.
PLoS One
; 8(4): e62114, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23630626
6.
Complement-mediated muscle cell lysis: a possible mechanism of myonecrosis in anti-SRP associated necrotizing myopathy (ASANM).
J Neuroimmunol
; 264(1-2): 65-70, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24041831
7.
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization.
Nat Genet
; 45(8): 902-906, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23817571
8.
Inactivation of a class A and a class C ß-lactamase by 6ß-(hydroxymethyl)penicillanic acid sulfone.
Biochem Pharmacol
; 83(4): 462-71, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22155308
9.
Potent inhibitors of LpxC for the treatment of Gram-negative infections.
J Med Chem
; 55(2): 914-23, 2012 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22175825
10.
Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections.
J Med Chem
; 55(4): 1662-70, 2012 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22257165
11.
One-pot (1-ethoxycarbonylcyclopropyl)triphenylphosphonium tetrafluoroborate ring-opening and Wittig reaction.
Org Lett
; 13(19): 5338-41, 2011 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21910461
12.
Synthesis and characterization of a trifunctional aminoamide cellulose derivative.
Biomacromolecules
; 7(1): 139-45, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16398508