Detalhe da pesquisa
1.
Discovery of pyrazolopyrimidine derivatives as novel inhibitors of ataxia telangiectasia and rad3 related protein (ATR).
Bioorg Med Chem Lett
; 27(4): 750-754, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28131712
2.
Temozolomide analogs with improved brain/plasma ratios - Exploring the possibility of enhancing the therapeutic index of temozolomide.
Bioorg Med Chem Lett
; 26(20): 5103-5109, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27614414
3.
Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide.
Breast Cancer Res
; 16(1): R7, 2014 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24451109
4.
Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration-resistant prostate cancer.
Prostate
; 73(12): 1291-305, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23765603
5.
Elucidating host cell response pathways and repurposing therapeutics for SARS-CoV-2 and other coronaviruses.
Sci Rep
; 12(1): 18811, 2022 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36335206
6.
Cognition-enhancing properties of Dimebon in a rat novel object recognition task are unlikely to be associated with acetylcholinesterase inhibition or N-methyl-D-aspartate receptor antagonism.
J Pharmacol Exp Ther
; 333(3): 748-57, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20194526
7.
Long-term effects of B-type natriuretic peptide infusion after acute myocardial infarction in a rat model.
J Cardiovasc Pharmacol
; 55(1): 14-20, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19858735
8.
Prolonged effects of B-type natriuretic peptide infusion on cardiac remodeling after sustained myocardial injury.
Am J Physiol Heart Circ Physiol
; 297(2): H708-17, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19525373
9.
Inhibition of p38alpha mitogen-activated protein kinase prevents the development of osteolytic bone disease, reduces tumor burden, and increases survival in murine models of multiple myeloma.
Cancer Res
; 67(10): 4572-7, 2007 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17495322
10.
Transforming growth factor-beta blockade down-regulates the renin-angiotensin system and modifies cardiac remodeling after myocardial infarction.
Endocrinology
; 149(11): 5828-34, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18653707
11.
p38alpha-selective mitogen-activated protein kinase inhibitor SD-282 reduces inflammation in a subchronic model of tobacco smoke-induced airway inflammation.
J Pharmacol Exp Ther
; 324(3): 921-9, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18056868
12.
p38alpha-selective MAP kinase inhibitor reduces tumor growth in mouse xenograft models of multiple myeloma.
Anticancer Res
; 28(6A): 3827-33, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-19189670
13.
Role of p38 mitogen activated protein kinase in a model of osteosarcoma-induced pain.
Pharmacol Biochem Behav
; 90(4): 664-75, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18584857
14.
Pharmacological properties of SD-282 - an alpha-isoform selective inhibitor for p38 MAP kinase.
Pharmacology
; 81(3): 204-20, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18176091
15.
B-Type natriuretic peptide inhibited angiotensin II-stimulated cholesterol biosynthesis, cholesterol transfer, and steroidogenesis in primary human adrenocortical cells.
Endocrinology
; 148(8): 3722-9, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17478552
16.
Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model.
Neuro Oncol
; 9(3): 259-70, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17522330
17.
Antitumor activity of TGF-beta inhibitor is dependent on the microenvironment.
Anticancer Res
; 27(6B): 4149-57, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18229422
18.
Restricted Delivery of Talazoparib Across the Blood-Brain Barrier Limits the Sensitizing Effects of PARP Inhibition on Temozolomide Therapy in Glioblastoma.
Mol Cancer Ther
; 16(12): 2735-2746, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28947502
19.
B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibroblasts: fibrosis, myofibroblast conversion, proliferation, and inflammation.
Circ Res
; 94(4): 453-61, 2004 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-14726474
20.
B-type natriuretic peptide for the treatment of congestive heart failure.
Curr Opin Pharmacol
; 2(2): 142-7, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11950624