Detalhe da pesquisa
1.
Challenges in distinguishing functional proteins from polyproteins in databases: implications for drug discovery.
Brief Bioinform
; 25(2)2024 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38305454
2.
Drug Potency Prediction of SARS-CoV-2 Main Protease Inhibitors Based on a Graph Generative Model.
Int J Mol Sci
; 24(10)2023 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37240128
3.
Identification of N-Acyl Hydrazones as New Non-Zinc-Binding MMP-13 Inhibitors by Structure-Based Virtual Screening Studies and Chemical Optimization.
Int J Mol Sci
; 24(13)2023 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446276
4.
The Mutational Landscape of SARS-CoV-2.
Int J Mol Sci
; 24(10)2023 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37240420
5.
Haste makes waste: A critical review of docking-based virtual screening in drug repurposing for SARS-CoV-2 main protease (M-pro) inhibition.
Med Res Rev
; 42(2): 744-769, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34697818
6.
Prediction of Recurrent Mutations in SARS-CoV-2 Using Artificial Neural Networks.
Int J Mol Sci
; 23(23)2022 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36499005
7.
A Review of the Current Landscape of SARS-CoV-2 Main Protease Inhibitors: Have We Hit the Bullseye Yet?
Int J Mol Sci
; 23(1)2021 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35008685
8.
Identification of Broad-Spectrum MMP Inhibitors by Virtual Screening.
Molecules
; 26(15)2021 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34361703
9.
Prediction of Novel Inhibitors of the Main Protease (M-pro) of SARS-CoV-2 through Consensus Docking and Drug Reposition.
Int J Mol Sci
; 21(11)2020 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32471205
10.
The Light and Dark Sides of Virtual Screening: What Is There to Know?
Int J Mol Sci
; 20(6)2019 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30893780
11.
Activity and selectivity cliffs for DPP-IV inhibitors: Lessons we can learn from SAR studies and their application to virtual screening.
Med Res Rev
; 38(6): 1874-1915, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29660786
12.
Tools for in silico target fishing.
Methods
; 71: 98-103, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25277948
13.
Molecular fingerprint similarity search in virtual screening.
Methods
; 71: 58-63, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25132639
14.
Ligand- and Structure-Based Virtual Screening Identifies New Inhibitors of the Interaction of the SARS-CoV-2 Spike Protein with the ACE2 Host Receptor.
Pharmaceutics
; 16(5)2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38794275
15.
DecoyFinder: an easy-to-use python GUI application for building target-specific decoy sets.
Bioinformatics
; 28(12): 1661-2, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22539671
16.
Recent advances in the development of methyltransferase (MTase) inhibitors against (re)emerging arboviruses diseases dengue and Zika.
Eur J Med Chem
; 252: 115290, 2023 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36958266
17.
The lipid-lowering effect of dietary proanthocyanidins in rats involves both chylomicron-rich and VLDL-rich fractions.
Br J Nutr
; 108(2): 208-17, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22011563
18.
Structural insights for the design of new PPARgamma partial agonists with high binding affinity and low transactivation activity.
J Comput Aided Mol Des
; 25(8): 717-28, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21691811
19.
Anti-Inflammatory and Immunomodulatory Effects of the Grifola frondosa Natural Compound o-Orsellinaldehyde on LPS-Challenged Murine Primary Glial Cells. Roles of NF-κß and MAPK.
Pharmaceutics
; 13(6)2021 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34071571
20.
Understanding the variability of the S1' pocket to improve matrix metalloproteinase inhibitor selectivity profiles.
Drug Discov Today
; 25(1): 38-57, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31513929