Detalhe da pesquisa
1.
Mechanisms of 8-aminoquinoline induced haemolytic toxicity in a G6PDd humanized mouse model.
J Cell Mol Med
; 26(13): 3675-3686, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35665597
2.
Measurements of 5,6-Orthoquinone, a Surrogate for the Presumed Active Primaquine Metabolite 5-Hydroxyprimaquine, in the Urine of Cambodian Adults.
Antimicrob Agents Chemother
; 66(3): e0182121, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34978892
3.
Safety, Pharmacokinetics, and Activity of High-Dose Ivermectin and Chloroquine against the Liver Stage of Plasmodium cynomolgi Infection in Rhesus Macaques.
Antimicrob Agents Chemother
; 64(9)2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32660993
4.
Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
J Infect Dis
; 220(11): 1761-1770, 2019 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31549155
5.
Comparison of Anti-Xa Activity in Patients Receiving Apixaban or Rivaroxaban.
Ann Pharmacother
; 52(3): 251-256, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29047306
6.
Pre-clinical evaluation of CYP 2D6 dependent drug-drug interactions between primaquine and SSRI/SNRI antidepressants.
Malar J
; 15(1): 280, 2016 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27188854
7.
Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site.
Proc Natl Acad Sci U S A
; 110(28): E2552-61, 2013 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23798390
8.
Corrigendum to: Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
J Infect Dis
; 221(7): 1204, 2020 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31773155
9.
Differential cytochrome P450 2D metabolism alters tafenoquine pharmacokinetics.
Antimicrob Agents Chemother
; 59(7): 3864-9, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25870069
10.
Differential CYP 2D6 metabolism alters primaquine pharmacokinetics.
Antimicrob Agents Chemother
; 59(4): 2380-7, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25645856
11.
Investigation into novel thiophene- and furan-based 4-amino-7-chloroquinolines afforded antimalarials that cure mice.
Bioorg Med Chem
; 23(9): 2176-86, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25801154
12.
Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections.
Malar J
; 13: 141, 2014 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24731238
13.
Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds.
Malar J
; 13: 2, 2014 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24386891
14.
Enantioselective metabolism of primaquine by human CYP2D6.
Malar J
; 13: 507, 2014 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25518709
15.
Liver-targeted polymeric prodrugs delivered subcutaneously improve tafenoquine therapeutic window for malaria radical cure.
Sci Adv
; 10(16): eadk4492, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38640243
16.
Discovery and Optimization of Tambjamines as a Novel Class of Antileishmanial Agents.
J Med Chem
; 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38722757
17.
CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever.
Malar J
; 12: 214, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23800033
18.
The metabolism of primaquine to its active metabolite is dependent on CYP 2D6.
Malar J
; 12: 212, 2013 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23782898
19.
A Review of Omadacycline for Potential Utility in the Military Health System for the Treatment of Wound Infections.
Mil Med
; 2023 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37963013
20.
CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.
Malar J
; 11: 259, 2012 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22856549