Detalhe da pesquisa
1.
Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.
Am J Hum Genet
; 94(4): 586-98, 2014 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24702955
2.
Structure-activity-relationship of amide and sulfonamide analogs of omarigliptin.
Bioorg Med Chem Lett
; 25(24): 5767-71, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26546218
3.
Development of a novel class of potent and selective FIXa inhibitors.
Bioorg Med Chem Lett
; 25(21): 4945-4949, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25978966
4.
A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus.
PLoS Genet
; 7(6): e1002128, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21738483
5.
Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
PLoS Genet
; 7(5): e1002079, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21637784
6.
Novel tetrahydropyran analogs as dipeptidyl peptidase IV inhibitors: Profile of clinical candidate (2R,3S,5R)-2- (2,5-difluorophenyl)-5-(4,6-dihydropyrrolo [3,4-c]pyrazol-5-(1H)-yl)tetrahydro-2H-pyran-3-amine (23) [corrected].
Bioorg Med Chem Lett
; 23(19): 5361-6, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23972441
7.
Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.
PLoS Genet
; 6(2): e1000841, 2010 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20169177
8.
Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus.
Proc Natl Acad Sci U S A
; 107(36): 15838-43, 2010 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20733074
9.
Association of a functional IRF7 variant with systemic lupus erythematosus.
Arthritis Rheum
; 63(3): 749-54, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21360504
10.
Recombinant human growth hormone in the treatment of C.836A/G-caused short stature in a girl: a case report and literature review.
Transl Pediatr
; 11(5): 774-780, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35685070
11.
Determination of modification sites and relative quantitation in large protein conjugation via automated data processing.
J Pharm Biomed Anal
; 198: 113995, 2021 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33706146
12.
Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases.
Rheumatology (Oxford)
; 49(7): 1239-44, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20338887
13.
Discovery of new binding elements in DPP-4 inhibition and their applications in novel DPP-4 inhibitor design.
Bioorg Med Chem Lett
; 18(13): 3706-10, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18524582
14.
N-alkyl-4-piperidinyl-2,3-diarylpyrrole derivatives with heterocyclic substitutions as potent and broad spectrum anticoccidial agents.
Bioorg Med Chem Lett
; 18(6): 2019-22, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18276140
15.
Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9.
Diabetes
; 54(10): 2988-94, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16186403
16.
Omarigliptin (MK-3102): a novel long-acting DPP-4 inhibitor for once-weekly treatment of type 2 diabetes.
J Med Chem
; 57(8): 3205-12, 2014 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24660890
17.
Association of FcγRIIIa-158V/F with systemic lupus erythematosus in a Chinese population.
Int J Rheum Dis
; 16(6): 685-91, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24131500
18.
Optimization of 1,4-diazepan-2-one containing dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes.
Bioorg Med Chem Lett
; 17(7): 1903-7, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17291750
19.
Synthesis and SAR studies of potent imidazopyridine anticoccidial agents.
Bioorg Med Chem Lett
; 17(13): 3558-61, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17475489
20.
(3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
Bioorg Med Chem Lett
; 17(1): 49-52, 2007 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17055272