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1.
BMC Health Serv Res ; 21(1): 917, 2021 Sep 05.
Artigo em Inglês | MEDLINE | ID: mdl-34482842

RESUMO

BACKGROUND: Significant resources are spent on hospital accreditation worldwide. However, documentation of the effects of accreditation on processes, quality of care and outcomes in healthcare remain scarce. This study aimed to examine changes in the delivery of patient care in accordance with clinical guidelines (recommended care) after first-time accreditation in a care setting not previously exposed to systematic quality improvement initiatives. METHODS: We conducted a before and after study based on medical record reviews in connection with introducing first-time accreditation. We included patients with stroke/transient ischemic attack, bleeding gastric ulcer, diabetes, chronic obstructive pulmonary disease (COPD), childbirth, heart failure and hip fracture treated at public, non-psychiatric Faroese hospitals during 2012-2013 (before accreditation) or 2017-2018 (after accreditation). The intervention was the implementation of a modified second version of The Danish Healthcare Quality Program (DDKM) from 2014 to 2016 including an on-site accreditation survey in the Faroese hospitals. Recommended care was assessed using 63 disease specific patient level process performance measures in seven clinical conditions. We calculated the fulfillment and changes in the opportunity-based composite score and the all-or-none score. RESULTS: We included 867 patient pathways (536 before and 331 after). After accreditation, the total opportunity-based composite score was marginally higher though the change did not reach statistical significance (adjusted percentage point difference (%): 4.4%; 95% CI: - 0.7 to 9.6). At disease level, patients with stroke/transient ischemic attack, bleeding gastric ulcer, COPD and childbirth received a higher proportion of recommended care after accreditation. No difference was found for heart failure and diabetes. Hip fracture received less recommended care after accreditation. The total all-or-none score, which is the probability of a patient receiving all recommended care, was significantly higher after accreditation (adjusted relative risk (RR): 2.32; 95% CI: 2.03 to 2.67). The improvement was particularly strong for patients with COPD (RR: 16.22; 95% CI: 14.54 to 18.10). CONCLUSION: Hospitals were in general more likely to provide recommended care after first-time accreditation.


Assuntos
Acreditação , Insuficiência Cardíaca , Dinamarca , Hospitais Públicos , Humanos , Melhoria de Qualidade
2.
Physiol Rep ; 10(13): e15382, 2022 07.
Artigo em Inglês | MEDLINE | ID: mdl-35822425

RESUMO

Angiotensin-converting enzyme (ACE) activity may be one determinant of adaptability to exercise training, but well-controlled studies in humans without confounding conditions are lacking. Thus, the purpose of the present study was to investigate whether ACE inhibition affects cardiovascular adaptations to exercise training in healthy humans. Healthy participants of both genders (40 ± 7 years) completed a randomized, double-blind, placebo-controlled trial. Eight weeks of exercise training combined with placebo (PLA, n = 25) or ACE inhibitor (ACEi, n = 23) treatment was carried out. Before and after the intervention, cardiovascular characteristics were investigated. Mean arterial blood pressure was reduced (p < 0.001) by -5.5 [-8.4; -2.6] mmHg in ACEi , whereas the 0.7 [-2.0; 3.5] mmHg fluctuation in PLA was non-significant. Maximal oxygen uptake increased (p < 0.001) irrespective of ACE inhibitor treatment by 13 [8; 17] % in ACEi and 13 [9; 17] % in PLA. In addition, skeletal muscle endurance increased (p < 0.001) to a similar extent in both groups, with magnitudes of 82 [55; 113] % in ACEi and 74 [48; 105] % in PLA. In contrast, left atrial volume decreased (p < 0.05) by -9 [-16; -2] % in ACEi , but increased (p < 0.01) by 14 [5; 23] % in PLA. Total hemoglobin mass was reduced (p < 0.01) by -3 [-6; -1] % in ACEi , while a non-significant numeric increase of 2 [-0.4; 4] % existed in PLA. The lean mass remained constant in ACEi but increased (p < 0.001) by 3 [2; 4] % in PLA. In healthy middle-aged adults, 8 weeks of high-intensity exercise training increases maximal oxygen uptake and skeletal muscle endurance irrespective of ACE inhibitor treatment. However, ACE inhibitor treatment counteracts exercise training-induced increases in lean mass and left atrial volume. ACE inhibitor treatment compromises total hemoglobin mass.


Assuntos
Inibidores da Enzima Conversora de Angiotensina , Sistema Cardiovascular , Exercício Físico , Adulto , Inibidores da Enzima Conversora de Angiotensina/administração & dosagem , Sistema Cardiovascular/efeitos dos fármacos , Método Duplo-Cego , Exercício Físico/fisiologia , Feminino , Hemoglobinas/metabolismo , Humanos , Masculino , Pessoa de Meia-Idade , Oxigênio/metabolismo
3.
J Aging Stud ; 59: 100968, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34794713

RESUMO

This paper addresses self-presentation among home-dwelling octogenarians living in the Faroe Islands. The purpose was to examine how older adults make meaning of ageing in interaction and examine the possible impact of social and cultural norms on this meaning making practice. The study is based on social constructionism. Interviews were conducted with both married couples and individual men and women during the spring of 2019. The interviewees projected a positive impression of life as older adults. They used humour to cover up health problems, and downward social comparison with others to enhance their own active lifestyle. They included third-party compliments to enhance the impression of appearing 'younger' than their chronological age, thus reconciling the misalignment between age norms and lived experience.


Assuntos
Envelhecimento , Cônjuges , Idoso , Idoso de 80 Anos ou mais , Dinamarca , Feminino , Humanos , Masculino
4.
Sci Rep ; 9(1): 13909, 2019 09 26.
Artigo em Inglês | MEDLINE | ID: mdl-31558765

RESUMO

Primary carnitine deficiency (PCD) not treated with L-Carnitine can lead to sudden cardiac death. To our knowledge, it is unknown if asymptomatic patients treated with L-Carnitine suffer from myocardial scarring and thus be at greater risk of potentially serious arrhythmia. Cardiac evaluation of function and myocardial scarring is non-invasively best supported by cardiac magnetic resonance imaging (CMR) with late gadolinium enhancement (LGE). The study included 36 PCD patients, 17 carriers and 17 healthy subjects. A CMR cine stack in the short-axis plane were acquired to evaluate left ventricle (LV) systolic and diastolic function and a similar LGE stack to evaluate myocardial scarring and replacement fibrosis. LV volumes and ejection fraction were not different between PCD patients, carriers and healthy subjects. However, LV mass was higher in PCD patients with the severe homozygous mutation, c.95 A > G (p = 0.037; n = 17). Among homozygous PCD patients there were two cases of unexplained myocardial scarring and this is in contrast to no myocardial scarring in any of the other study participants (p = 0.10). LV mass was increased in PCD patients. L-carnitine supplementation is essential in order to prevent potentially lethal cardiac arrhythmia and serious adverse cardiac remodeling.


Assuntos
Carnitina/deficiência , Cicatriz/epidemiologia , Coração/diagnóstico por imagem , Imageamento por Ressonância Magnética , Doenças Musculares/diagnóstico por imagem , Miocárdio/patologia , Adulto , Carnitina/genética , Cicatriz/diagnóstico por imagem , Meios de Contraste , Feminino , Gadolínio , Heterozigoto , Homozigoto , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Musculares/genética , Doenças Musculares/patologia , Mutação , Função Ventricular
5.
Int J Circumpolar Health ; 78(1): 1653139, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31429677

RESUMO

Objectives: Longer life expectancies imply increased prevalence of heart failure. Blittle is known about the maintenance of disease specific knowledge following patient education. Our aim was to investigate if self-care and heart failure knowledge persists at 9 month follow up among patients with heart failure after an outpatient programme in the Faroe Islands. Methods: A prospective cohort study with patients recently diagnosed with heart failure were recruited and evaluated by questionnaire at baseline, after 3 and 9 months using The European Heart Failure Self-Care Behaviour Scale and the Dutch Heart Failure Knowledge Scale. Clinical and demographic information was collected. Results: Seven (15%) women and 40 (85%) men with heart failure and NYHA > 2 were included. There was an overall improvement in patients' self-care from baseline 25 (8) to 3 months 15 (5) and to 9 months (16 (45); both p < 0.001). Mean knowledge score 10 (3) improved to 13 (2) at 3 months and 12 (2) at 9 months (both p < 0.001). Conclusions: Disease specific patient education is applicable to heart failure patients, which can produce persistent improvements in self-care and knowledge after multidisciplinary outpatient programme. Practice Implications: Multidisciplinary outpatient programmes are beneficial for patients with heart failure and alters disease specific knowledge and self-care.


Assuntos
Assistência Ambulatorial/métodos , Conhecimentos, Atitudes e Prática em Saúde , Insuficiência Cardíaca/terapia , Autocuidado/psicologia , Idoso , Assistência Ambulatorial/estatística & dados numéricos , Dinamarca , Escolaridade , Feminino , Insuficiência Cardíaca/psicologia , Humanos , Masculino , Pessoa de Meia-Idade , Educação de Pacientes como Assunto/estatística & dados numéricos , Estudos Prospectivos , Autocuidado/estatística & dados numéricos , Inquéritos e Questionários
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