Detalhe da pesquisa
1.
Immunization of Mice with Virus-Like Vesicles of Kaposi Sarcoma-Associated Herpesvirus Reveals a Role for Antibodies Targeting ORF4 in Activating Complement-Mediated Neutralization.
J Virol
; 97(2): e0160022, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36757205
2.
Deoxycytidine kinase (dCK) inhibition is synthetic lethal with BRCA2 deficiency.
Drug Resist Updat
; 67: 100932, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36706533
3.
STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [18F]FLT PET imaging.
Proc Natl Acad Sci U S A
; 118(36)2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34480004
4.
NAD+ depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition.
Proc Natl Acad Sci U S A
; 118(8)2021 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33597293
5.
Targeting deoxycytidine kinase improves symptoms in mouse models of multiple sclerosis.
Immunology
; 168(1): 152-169, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35986643
6.
Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy.
Proc Natl Acad Sci U S A
; 117(26): 15172-15181, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32532924
7.
Lysosome inhibition sensitizes pancreatic cancer to replication stress by aspartate depletion.
Proc Natl Acad Sci U S A
; 116(14): 6842-6847, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30894490
8.
Detection of immune responses after immunotherapy in glioblastoma using PET and MRI.
Proc Natl Acad Sci U S A
; 114(38): 10220-10225, 2017 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28874539
9.
Activity and electrochemical properties: iron complexes of the anticancer drug triapine and its analogs.
J Biol Inorg Chem
; 24(5): 621-632, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31250199
10.
[18F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity.
Proc Natl Acad Sci U S A
; 113(15): 4027-32, 2016 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27035974
11.
Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the molecules.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 1): 68-78, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24419380
12.
In vivo imaging of therapy-induced anti-cancer immune responses in humans.
Cell Mol Life Sci
; 70(13): 2237-57, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23052208
13.
Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.
Proc Natl Acad Sci U S A
; 108(51): E1408-16, 2011 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22123951
14.
Targeting host deoxycytidine kinase mitigates Staphylococcus aureus abscess formation.
Elife
; 122024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38512723
15.
Structure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe.
J Biol Chem
; 287(1): 446-454, 2012 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22074768
16.
Targeted noninvasive imaging of the innate immune response.
Proc Natl Acad Sci U S A
; 112(19): 5868-9, 2015 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25934920
17.
Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses.
Proc Natl Acad Sci U S A
; 107(32): 14286-91, 2010 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20624956
18.
Requirement for deoxycytidine kinase in T and B lymphocyte development.
Proc Natl Acad Sci U S A
; 107(12): 5551-6, 2010 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20080663
19.
Looking for the unexpected in purine and pyrimidine metabolism.
Nucleosides Nucleotides Nucleic Acids
; : 1-9, 2023 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37874224
20.
Targeting host deoxycytidine kinase mitigates Staphylococcus aureus abscess formation.
bioRxiv
; 2023 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37645972