Detalhe da pesquisa
1.
Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer's disease.
Alzheimers Dement
; 17(12): 1976-1987, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33984181
2.
Preliminary Results of a Trial of Atabecestat in Preclinical Alzheimer's Disease.
N Engl J Med
; 380(15): 1483-1485, 2019 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30970197
3.
Counterpoint to Jin et al, On weighted composite scores for early Alzheimer's trials. Pharm Stat. 18 (2):239-47, 2019, DOI: 10.1002/pst.1920.
Pharm Stat
; 19(4): 492-493, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32147862
4.
Optimal composite scores for longitudinal clinical trials under the linear mixed effects model.
Pharm Stat
; 14(5): 418-26, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26223663
5.
Disease progression model in subjects with mild cognitive impairment from the Alzheimer's disease neuroimaging initiative: CSF biomarkers predict population subtypes.
Br J Clin Pharmacol
; 75(1): 146-61, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22534009
6.
The ADAS-Cog revisited: novel composite scales based on ADAS-Cog to improve efficiency in MCI and early AD trials.
Alzheimers Dement
; 9(1 Suppl): S21-31, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23127469
7.
Sparse learning and stability selection for predicting MCI to AD conversion using baseline ADNI data.
BMC Neurol
; 12: 46, 2012 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22731740
8.
Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial.
JAMA Neurol
; 78(3): 293-301, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33464300
9.
Protocol of the Cognitive Health in Ageing Register: Investigational, Observational and Trial Studies in Dementia Research (CHARIOT): Prospective Readiness cOhort (PRO) SubStudy.
BMJ Open
; 11(6): e043114, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34168021
10.
Genome-wide copy number alterations detection in fresh frozen and matched FFPE samples using SNP 6.0 arrays.
Genes Chromosomes Cancer
; 47(11): 957-64, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18663747
11.
The high-level similarity of some disparate gene expression measures.
Bioinformatics
; 23(22): 3032-8, 2007 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17893087
12.
ABC gene-ranking for prediction of drug-induced cholestasis in rats.
Toxicol Rep
; 3: 252-261, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28959545
13.
Optimizing regions-of-interest composites for capturing treatment effects on brain amyloid in clinical trials.
J Alzheimers Dis
; 43(3): 809-21, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25114074
14.
Development and evaluation of a multiplexed mass spectrometry based assay for measuring candidate peptide biomarkers in Alzheimer's Disease Neuroimaging Initiative (ADNI) CSF.
Proteomics Clin Appl
; 9(7-8): 715-31, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25676562
15.
Novel Statistically-Derived Composite Measures for Assessing the Efficacy of Disease-Modifying Therapies in Prodromal Alzheimer's Disease Trials: An AIBL Study.
J Alzheimers Dis
; 46(4): 1079-89, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26402634
16.
Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study.
Alzheimers Dement (Amst)
; 1(3): 339-348, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26693175
17.
Disease progression model for Clinical Dementia Rating-Sum of Boxes in mild cognitive impairment and Alzheimer's subjects from the Alzheimer's Disease Neuroimaging Initiative.
Neuropsychiatr Dis Treat
; 10: 929-52, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24926196
18.
Coalition Against Major Diseases: Precompetitive Collaborations and Regulatory Paths to Accelerating Drug Development for Neurodegenerative Diseases.
Ther Innov Regul Sci
; 47(6): 632-638, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30235546
19.
An improved model for disease progression in patients from the Alzheimer's disease neuroimaging initiative.
J Clin Pharmacol
; 52(5): 629-44, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21659625
20.
A novel subject synchronization clinical trial design for Alzheimer's disease.
J Alzheimers Dis
; 31(3): 507-16, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22614878