Pesquisa | Biblioteca Virtual em Saúde

1.

Insulin sensitivity and beta cell function after Duodenal Mucosal Resurfacing (DMR): An Open-Label, Mechanistic, Pilot Study.

Busch, Celine B E; Meiring, Suzanne; van Baar, Annieke C G; Gastaldelli, Amalia; DeFronzo, Ralph; Mingrone, Geltrude; Hagen, Moira; White, Kelly; Rajagopalan, Harith; Nieuwdorp, Max; Bergman, Jacques J G H M.

Gastrointest Endosc ; 2024 Jan 25.

Artigo em Inglês | MEDLINE | ID: mdl-38280531

2.

Safety and efficacy of hydrothermal duodenal mucosal resurfacing in patients with type 2 diabetes: the randomised, double-blind, sham-controlled, multicentre REVITA-2 feasibility trial.

Mingrone, Geltrude; van Baar, Annieke Cg; Devière, Jacques; Hopkins, David; Moura, Eduardo; Cercato, Cintia; Rajagopalan, Harith; Lopez-Talavera, Juan Carlos; White, Kelly; Bhambhani, Vijeta; Costamagna, Guido; Haidry, Rehan; Grecco, Eduardo; Galvao Neto, Manoel; Aithal, Guruprasad; Repici, Alessandro; Hayee, Bu'Hussain; Haji, Amyn; Morris, A John; Bisschops, Raf; Chouhan, Manil D; Sakai, Naomi S; Bhatt, Deepak L; Sanyal, Arun J; Bergman, J J G H M.

Gut ; 71(2): 254-264, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-33597157

3.

Duodenal mucosal resurfacing: proof-of-concept, procedural development, and initial implementation in the clinical setting.

Haidry, Rehan J; van Baar, Annieke C; Galvao Neto, Manoel P; Rajagopalan, Harith; Caplan, Jay; Levin, Philip S; Bergman, Jacques J; Rodriguez, Leonardo; Deviere, Jacques; Thompson, Christopher C.

Gastrointest Endosc ; 90(4): 673-681.e2, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-30935932

4.

Bariatrics and endoscopic therapies for the treatment of metabolic disease: Past, present, and future.

Mingrone, Geltrude; Rajagopalan, Harith.

Diabetes Res Clin Pract ; 211: 111651, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38580037

5.

The significance of unstable chromosomes in colorectal cancer.

Rajagopalan, Harith; Nowak, Martin A; Vogelstein, Bert; Lengauer, Christoph.

Nat Rev Cancer ; 3(9): 695-701, 2003 09.

Artigo em Inglês | MEDLINE | ID: mdl-12951588

6.

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

Bachman, Kurtis E; Park, Ben Ho; Rhee, Ina; Rajagopalan, Harith; Herman, James G; Baylin, Stephen B; Kinzler, Kenneth W; Vogelstein, Bert.

Cancer Cell ; 3(1): 89-95, 2003 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-12559178

7.

A Gut-Centric Model of Metabolic Homeostasis.

Rajagopalan, Harith; Lopez-Talavera, Juan Carlos; Klonoff, David C; Cherrington, Alan D.

J Diabetes Sci Technol ; 16(6): 1567-1574, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-34697950

8.

Durable metabolic improvements 2 years after duodenal mucosal resurfacing (DMR) in patients with type 2 diabetes (REVITA-1 Study).

van Baar, Annieke C G; Devière, Jacques; Hopkins, David; Crenier, Laurent; Holleman, Frits; Galvão Neto, Manoel P; Becerra, Pablo; Vignolo, Paulina; Rodriguez Grunert, Leonardo; Mingrone, Geltrude; Costamagna, Guido; Nieuwdorp, Max; Guidone, Caterina; Haidry, Rehan J; Hayee, Bu; Magee, Cormac; Carlos Lopez-Talavera, Juan; White, Kelly; Bhambhani, Vijeta; Cozzi, Emily; Rajagopalan, Harith; J G H M Bergman, Jacques.

Diabetes Res Clin Pract ; 184: 109194, 2022 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-35032562

9.

Chronic peptide-based GIP receptor inhibition exhibits modest glucose metabolic changes in mice when administered either alone or combined with GLP-1 agonism.

West, Jason A; Tsakmaki, Anastasia; Ghosh, Soumitra S; Parkes, David G; Grønlund, Rikke V; Pedersen, Philip J; Maggs, David; Rajagopalan, Harith; Bewick, Gavin A.

PLoS One ; 16(3): e0249239, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33788878

10.

Aneuploidy and cancer.

Rajagopalan, Harith; Lengauer, Christoph.

Nature ; 432(7015): 338-41, 2004 Nov 18.

Artigo em Inglês | MEDLINE | ID: mdl-15549096

11.

Inactivation of hCDC4 can cause chromosomal instability.

Rajagopalan, Harith; Jallepalli, Prasad V; Rago, Carlo; Velculescu, Victor E; Kinzler, Kenneth W; Vogelstein, Bert; Lengauer, Christoph.

Nature ; 428(6978): 77-81, 2004 Mar 04.

Artigo em Inglês | MEDLINE | ID: mdl-14999283

12.

Hydrothermal Duodenal Mucosal Resurfacing: Role in the Treatment of Metabolic Disease.

Cherrington, Alan D; Rajagopalan, Harith; Maggs, David; Devière, Jacques.

Gastrointest Endosc Clin N Am ; 27(2): 299-311, 2017 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-28292408

13.

Endoscopic Duodenal Mucosal Resurfacing for the Treatment of Type 2 Diabetes: 6-Month Interim Analysis From the First-in-Human Proof-of-Concept Study.

Rajagopalan, Harith; Cherrington, Alan D; Thompson, Christopher C; Kaplan, Lee M; Rubino, Francesco; Mingrone, Geltrude; Becerra, Pablo; Rodriguez, Patricia; Vignolo, Paulina; Caplan, Jay; Rodriguez, Leonardo; Galvao Neto, Manoel P.

Diabetes Care ; 39(12): 2254-2261, 2016 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-27519448

14.

Linear model of colon cancer initiation.

Michor, Franziska; Iwasa, Yoh; Rajagopalan, Harith; Lengauer, Christoph; Nowak, Martin A.

Cell Cycle ; 3(3): 358-62, 2004 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-14726709

15.

CIN-ful cancers.

Rajagopalan, Harith; Lengauer, Christoph.

Cancer Chemother Pharmacol ; 54 Suppl 1: S65-8, 2004 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-15309517

16.

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.

Yun, Jihye; Rago, Carlo; Cheong, Ian; Pagliarini, Ray; Angenendt, Philipp; Rajagopalan, Harith; Schmidt, Kerstin; Willson, James K V; Markowitz, Sandy; Zhou, Shibin; Diaz, Luis A; Velculescu, Victor E; Lengauer, Christoph; Kinzler, Kenneth W; Vogelstein, Bert; Papadopoulos, Nickolas.

Science ; 325(5947): 1555-9, 2009 Sep 18.

Artigo em Inglês | MEDLINE | ID: mdl-19661383

17.

hCDC4 and genetic instability in cancer.

Rajagopalan, Harith; Lengauer, Christoph.

Cell Cycle ; 3(6): 693-4, 2004 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-15118416

18.

Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status.

Rajagopalan, Harith; Bardelli, Alberto; Lengauer, Christoph; Kinzler, Kenneth W; Vogelstein, Bert; Velculescu, Victor E.

Nature ; 418(6901): 934, 2002 Aug 29.

Artigo em Inglês | MEDLINE | ID: mdl-12198537

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Insulin sensitivity and beta cell function after Duodenal Mucosal Resurfacing (DMR): An Open-Label, Mechanistic, Pilot Study.

Safety and efficacy of hydrothermal duodenal mucosal resurfacing in patients with type 2 diabetes: the randomised, double-blind, sham-controlled, multicentre REVITA-2 feasibility trial.

Duodenal mucosal resurfacing: proof-of-concept, procedural development, and initial implementation in the clinical setting.

Bariatrics and endoscopic therapies for the treatment of metabolic disease: Past, present, and future.

The significance of unstable chromosomes in colorectal cancer.

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

A Gut-Centric Model of Metabolic Homeostasis.

Durable metabolic improvements 2 years after duodenal mucosal resurfacing (DMR) in patients with type 2 diabetes (REVITA-1 Study).

Chronic peptide-based GIP receptor inhibition exhibits modest glucose metabolic changes in mice when administered either alone or combined with GLP-1 agonism.

Aneuploidy and cancer.

Inactivation of hCDC4 can cause chromosomal instability.

Hydrothermal Duodenal Mucosal Resurfacing: Role in the Treatment of Metabolic Disease.

Endoscopic Duodenal Mucosal Resurfacing for the Treatment of Type 2 Diabetes: 6-Month Interim Analysis From the First-in-Human Proof-of-Concept Study.

Linear model of colon cancer initiation.

CIN-ful cancers.

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.

hCDC4 and genetic instability in cancer.

Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status.