Detalhe da pesquisa
1.
Immunomodulatory effect of Myrtenol on benzo (a) pyrene-induced lung cancer in Swiss albino mice via modulation of tumor markers, cytokines and inhibition of PCNA expression.
J Biochem Mol Toxicol
; 38(1): e23578, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37927152
2.
PathFX provides mechanistic insights into drug efficacy and safety for regulatory review and therapeutic development.
PLoS Comput Biol
; 14(12): e1006614, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30532240
3.
Genome-wide discovery of drug-dependent human liver regulatory elements.
PLoS Genet
; 10(10): e1004648, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25275310
4.
Dosing recommendations for pharmacogenetic interactions related to drug metabolism.
Pharmacogenet Genomics
; 26(7): 334-9, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27058883
5.
Statin Drug-Drug Interactions: Pharmacokinetic Basis of FDA Labeling Recommendations and Comparison Across Common Tertiary Clinical Resources.
J Clin Pharmacol
; 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38299698
6.
Regulation of microRNA expression by rifampin in human hepatocytes.
Drug Metab Dispos
; 41(10): 1763-8, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935064
7.
Optimization and validation of a capillary electrophoresis laser-induced fluorescence method for amino acids determination in human plasma: application to bipolar disorder study.
Electrophoresis
; 34(11): 1701-9, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23512402
8.
Inclusion of Subjects who are Obese in Drug Development: Current Status and Opportunities.
J Clin Pharmacol
; 63 Suppl 2: S10-S17, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37942907
9.
Promoting Clinical Trial Diversity: A Highlight of Select US FDA Initiatives.
Clin Pharmacol Ther
; 113(3): 528-535, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36514867
10.
US FDA Postmarketing Requirements and Commitments: A Systematic Assessment of Clinical Pharmacology Studies and Their Impact on US FDA Prescribing Information.
J Clin Pharmacol
; 63(6): 695-703, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36731882
11.
Pediatric dosing for locally acting drugs in submissions to the U.S. Food and Drug Administration between 2002 and 2020.
Clin Transl Sci
; 16(10): 2046-2057, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37551830
12.
Need for Representation of Pediatric Patients with Obesity in Clinical Trials.
Children (Basel)
; 10(10)2023 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37892303
13.
Cannabinoid receptor activation correlates with the proapoptotic action of the ß2-adrenergic agonist (R,R')-4-methoxy-1-naphthylfenoterol in HepG2 hepatocarcinoma cells.
J Pharmacol Exp Ther
; 343(1): 157-66, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22776956
14.
In silico and in vitro identification of microRNAs that regulate hepatic nuclear factor 4α expression.
Drug Metab Dispos
; 40(4): 726-33, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22232426
15.
The stereoselective sulfate conjugation of 4'-methoxyfenoterol stereoisomers by sulfotransferase enzymes.
Chirality
; 24(10): 796-803, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22744891
16.
Breast cancer resistance protein (BCRP/ABCG2) localises to the nucleus in glioblastoma multiforme cells.
Xenobiotica
; 42(8): 748-55, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22401348
17.
Stereoselective and regiospecific hydroxylation of ketamine and norketamine.
Xenobiotica
; 42(11): 1076-87, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22612619
18.
Racial and Ethnic Differences in Drug Disposition and Response: Review of New Molecular Entities Approved Between 2014 and 2019.
J Clin Pharmacol
; 62(4): 486-493, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34608640
19.
Clinical pharmacology information in regulatory submissions and labeling: A comparative analysis of orphan and non-orphan drugs approved by the FDA.
Clin Transl Sci
; 15(11): 2583-2596, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36165094
20.
Application of Solubility and Dissolution Profile Comparison for Prediction of Gastric pH-Mediated Drug-Drug Interactions.
AAPS J
; 24(1): 35, 2022 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35165814