1.
Dermatol Online J
; 30(2)2024 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38959922
RESUMO
Febrile ulceronecrotic Mucha-Habermann disease is a rare and severe variant of pityriasis lichenoides, characterized by sudden onset of generalized ulceronecrotic papules that rapidly coalesce into ulcers associated with high fever. Systemic manifestations such as intravascular disseminated coagulation and pulmonary, cardiac, gastrointestinal, and central nervous system involvement are common. Treatment is based on oral corticosteroids, immunosuppressive drugs such as methotrexate, and general supportive treatment. The present case describes a stepwise approach to a patient with Mucha-Habermann disease with insufficient response to methotrexate.
Assuntos
Metotrexato , Pitiríase Liquenoide , Humanos , Febre/etiologia , Herpes Simples , Imunossupressores/uso terapêutico , Metotrexato/uso terapêutico , Pitiríase Liquenoide/patologia , Pitiríase Liquenoide/tratamento farmacológico , Úlcera Cutânea/etiologia , Úlcera Cutânea/tratamento farmacológico , Úlcera Cutânea/patologia
2.
BMJ Case Rep
; 15(3)2022 03 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35296501