Detalhe da pesquisa
1.
Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer.
Proc Natl Acad Sci U S A
; 119(18): e2200143119, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35476525
2.
Mixed lineage kinase 3 and CD70 cooperation sensitize trastuzumab-resistant HER2+ breast cancer by ceramide-loaded nanoparticles.
Proc Natl Acad Sci U S A
; 119(38): e2205454119, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36095190
3.
Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity.
Proc Natl Acad Sci U S A
; 117(14): 7961-7970, 2020 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32209667
4.
Berberine Represses ß-Catenin Translation Involving 4E-BPs in Hepatocellular Carcinoma Cells.
Mol Pharmacol
; 99(1): 1-16, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33130557
5.
Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-Troglitazone-induced Apoptosis in Prostate Cancer Cells Involve AMP-activated Protein Kinase.
J Biol Chem
; 290(36): 21865-75, 2015 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26198640
6.
Human Epidermal Growth Factor Receptor 2 (HER2) Impedes MLK3 Kinase Activity to Support Breast Cancer Cell Survival.
J Biol Chem
; 290(35): 21705-12, 2015 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26152725
7.
Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function.
Proc Natl Acad Sci U S A
; 109(21): 8149-54, 2012 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566623
8.
Molecular Insights of MAP4K4 Signaling in Inflammatory and Malignant Diseases.
Cancers (Basel)
; 15(8)2023 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37190200
9.
Interplay between MAP kinases and tumor microenvironment: Opportunity for immunotherapy in pancreatic cancer.
Adv Cancer Res
; 159: 113-143, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37268394
10.
TrkA expression directs the anti-neoplastic activity of MLK3 inhibitors in triple-negative breast cancer.
Oncogene
; 42(14): 1132-1143, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36813855
11.
Mixed lineage kinase 3 modulates ß-catenin signaling in cancer cells.
J Biol Chem
; 286(43): 37470-82, 2011 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21880738
12.
Dysregulation of immune checkpoint proteins in hepatocellular carcinoma: Impact on metabolic reprogramming.
Curr Opin Pharmacol
; 64: 102232, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35526340
13.
Ets1 mediates sorafenib resistance by regulating mitochondrial ROS pathway in hepatocellular carcinoma.
Cell Death Dis
; 13(7): 581, 2022 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35789155
14.
The regulatory function of mixed lineage kinase 3 in tumor and host immunity.
Pharmacol Ther
; 219: 107704, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33045253
15.
Tumor-infiltrating CD8+ T cell antitumor efficacy and exhaustion: molecular insights.
Drug Discov Today
; 26(4): 951-967, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33450394
16.
Mixed Lineage Kinase 3 phosphorylates prolyl-isomerase PIN1 and potentiates GLI1 signaling in pancreatic cancer development.
Cancer Lett
; 515: 1-13, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34052323
17.
MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3.
Oncogene
; 40(43): 6153-6165, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34511598
18.
Transcription Factors in Cancer Development and Therapy.
Cancers (Basel)
; 12(8)2020 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32824207
19.
Correction: Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1.
Oncogene
; 39(3): 722, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31530933
20.
Mitogen-Activated Protein Kinase Inhibitors and T-Cell-Dependent Immunotherapy in Cancer.
Pharmaceuticals (Basel)
; 13(1)2020 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31936067