Detalhe da pesquisa
1.
Targeting autophagy impairment improves the phenotype of a novel CLN8 zebrafish model.
Neurobiol Dis
; 197: 106536, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38763444
2.
New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2.
Int J Mol Sci
; 24(3)2023 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36768458
3.
New Synthetic Methodology for Drug-like Molecules.
Molecules
; 28(15)2023 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37570616
4.
Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells.
Molecules
; 27(9)2022 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35566369
5.
Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment.
Cancer Cell Int
; 21(1): 318, 2021 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34167552
6.
Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects.
Bioorg Chem
; 107: 104572, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33418316
7.
Diphenyl-Methane Based Thyromimetic Inhibitors for Transthyretin Amyloidosis.
Int J Mol Sci
; 22(7)2021 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33800546
8.
TG68, a Novel Thyroid Hormone Receptor-ß Agonist for the Treatment of NAFLD.
Int J Mol Sci
; 22(23)2021 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884910
9.
Areca catechu-From farm to food and biomedical applications.
Phytother Res
; 34(9): 2140-2158, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32159263
10.
Endogenous 3-Iodothyronamine (T1AM) and Synthetic Thyronamine-like Analog SG-2 Act as Novel Pleiotropic Neuroprotective Agents Through the Modulation of SIRT6.
Molecules
; 25(5)2020 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32110992
11.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.
Molecules
; 25(13)2020 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32605268
12.
Lipolytic Effects of 3-Iodothyronamine (T1AM) and a Novel Thyronamine-Like Analog SG-2 through the AMPK Pathway.
Int J Mol Sci
; 20(16)2019 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31434215
13.
A review on the hybrids of hydroxycinnamic acid as multi-target-directed ligands against Alzheimer's disease.
Bioorg Med Chem
; 26(3): 543-550, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29310862
14.
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors.
Bioorg Med Chem Lett
; 27(21): 4812-4816, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28993050
15.
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD.
Bioorg Med Chem Lett
; 25(4): 807-10, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25597007
16.
Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications.
Bioorg Med Chem
; 23(3): 422-8, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25577707
17.
Synthetic Thyroid Hormone Receptor-ß Agonists Promote Oligodendrocyte Precursor Cell Differentiation in the Presence of Inflammatory Challenges.
Pharmaceuticals (Basel)
; 16(9)2023 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37765015
18.
Potential use of TG68 - A novel thyromimetic - for the treatment of non-alcoholic fatty liver (NAFLD)-associated hepatocarcinogenesis.
Front Oncol
; 13: 1127517, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36910628
19.
Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.
Bioorg Med Chem Lett
; 22(20): 6498-502, 2012 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22981331
20.
Development of classification models for identifying "true" P-glycoprotein (P-gp) inhibitors through inhibition, ATPase activation and monolayer efflux assays.
Int J Mol Sci
; 13(6): 6924-6943, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22837672