Detalhe da pesquisa
1.
Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia.
Blood
; 118(3): 693-702, 2011 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21628411
2.
Structure-activity relationships for 4-anilinoquinoline derivatives as inhibitors of the DNA methyltransferase enzyme DNMT1.
Bioorg Med Chem
; 21(11): 3147-53, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23639684
3.
Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells.
Blood
; 114(19): 4150-7, 2009 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19734450
4.
S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis).
J Transl Med
; 8: 92, 2010 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20932295
5.
Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides.
Cancer Res
; 67(13): 6400-8, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17616700
6.
Retraction: A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation.
Cancer Res
; 83(24): 4180, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38098454
7.
Transbuccal delivery of 5-aza-2 -deoxycytidine: effects of drug concentration, buffer solution, and bile salts on permeation.
AAPS PharmSciTech
; 8(3): E55, 2007 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-17915805
8.
MET/HGF Coexpression as a Novel Predictive Biomarker for Response to MET Inhibitor Therapy in a Case of Psammomatous Melanotic Schwannoma.
JCO Precis Oncol
; 6: e2200096, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35675576
9.
Phase 1B study of amuvatinib in combination with five standard cancer therapies in adults with advanced solid tumors.
Cancer Chemother Pharmacol
; 74(1): 195-204, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24849582
10.
Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase.
J Med Chem
; 57(6): 2582-8, 2014 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24520856
11.
A phase I, first-in-human dose-escalation study of amuvatinib, a multi-targeted tyrosine kinase inhibitor, in patients with advanced solid tumors.
Cancer Chemother Pharmacol
; 71(2): 463-71, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23178951
12.
Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines.
J Hematol Oncol
; 6: 92, 2013 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24326130
13.
Safety, tolerability, and pharmacokinetics of amuvatinib from three phase 1 clinical studies in healthy volunteers.
Cancer Chemother Pharmacol
; 70(1): 183-90, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22349808
14.
Erratum to: Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines.
J Hematol Oncol
; 9(1): 110, 2016 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27737688
15.
S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth.
Mol Cancer Ther
; 9(5): 1443-50, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20442312
16.
Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes.
Mol Cancer Ther
; 8(10): 2882-93, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19825806
17.
A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation.
Cancer Res
; 69(10): 4277-85, 2009 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19417133
18.
Oral decitabine reactivates expression of the methylated gamma-globin gene in Papio anubis.
Am J Hematol
; 82(11): 981-5, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17696208
19.
Expect the unexpected-screen your screens.
J Pharm Sci
; 100(5): 1996, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21374629