Detalhe da pesquisa
1.
Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins.
J Cell Sci
; 135(2)2022 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34982109
2.
Transplanted human neural stem cells rescue phenotypes in zQ175 Huntington's disease mice and innervate the striatum.
Mol Ther
; 31(12): 3545-3563, 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37807512
3.
PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease.
Proc Natl Acad Sci U S A
; 118(4)2021 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33468657
4.
Treatment with JQ1, a BET bromodomain inhibitor, is selectively detrimental to R6/2 Huntington's disease mice.
Hum Mol Genet
; 29(2): 202-215, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31696228
5.
Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease.
Brain
; 143(1): 266-288, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31848580
6.
Aberrant splicing in Huntington's disease via disrupted TDP-43 activity accompanied by altered m6A RNA modification.
bioRxiv
; 2023 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961595
7.
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Nat Commun
; 13(1): 7791, 2022 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36543778
8.
Impaired intestinal vitamin B1 (thiamin) uptake in thiamin transporter-2-deficient mice.
Gastroenterology
; 138(5): 1802-9, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19879271
9.
Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization.
J Clin Invest
; 131(12)2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33945510
10.
N-Glycosylation is required for Na+-dependent vitamin C transporter functionality.
Biochem Biophys Res Commun
; 374(1): 123-7, 2008 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18619416
11.
Therapeutic effects of stem cells in rodent models of Huntington's disease: Review and electrophysiological findings.
CNS Neurosci Ther
; 24(4): 329-342, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29512295
12.
Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice.
Stem Cell Reports
; 10(1): 58-72, 2018 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29233555
13.
Functional analysis of two regulatory regions of the human Na+ -dependent vitamin C transporter 2, SLC23A2, in human vascular smooth muscle cells.
Biochim Biophys Acta
; 1732(1-3): 76-81, 2005 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-16380174
14.
PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo.
Neuron
; 90(3): 507-20, 2016 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27146268
15.
Cellular and molecular aspects of thiamin uptake by human liver cells: studies with cultured HepG2 cells.
Biochim Biophys Acta
; 1567(1-2): 106-12, 2002 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-12488043
16.
Expression and promoter analysis of SLC19A2 in the human intestine.
Biochim Biophys Acta
; 1561(2): 180-7, 2002 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-11997118
17.
Promoter analysis of the human ascorbic acid transporters SVCT1 and 2: mechanisms of adaptive regulation in liver epithelial cells.
J Nutr Biochem
; 22(4): 344-50, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20471816
18.
Differentiation-dependent regulation of the intestinal folate uptake process: studies with Caco-2 cells and native mouse intestine.
Am J Physiol Cell Physiol
; 295(3): C828-35, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18650265
19.
Mechanisms and regulation of vitamin C uptake: studies of the hSVCT systems in human liver epithelial cells.
Am J Physiol Gastrointest Liver Physiol
; 295(6): G1217-27, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18845575
20.
Regulation of the human biotin transporter hSMVT promoter by KLF-4 and AP-2: confirmation of promoter activity in vivo.
Am J Physiol Cell Physiol
; 292(4): C1305-12, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17135299