Pesquisa | Biblioteca Virtual em Saúde

1.

Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs.

Hadi, Kevin; Yao, Xiaotong; Behr, Julie M; Deshpande, Aditya; Xanthopoulakis, Charalampos; Tian, Huasong; Kudman, Sarah; Rosiene, Joel; Darmofal, Madison; DeRose, Joseph; Mortensen, Rick; Adney, Emily M; Shaiber, Alon; Gajic, Zoran; Sigouros, Michael; Eng, Kenneth; Wala, Jeremiah A; Wrzeszczynski, Kazimierz O; Arora, Kanika; Shah, Minita; Emde, Anne-Katrin; Felice, Vanessa; Frank, Mayu O; Darnell, Robert B; Ghandi, Mahmoud; Huang, Franklin; Dewhurst, Sally; Maciejowski, John; de Lange, Titia; Setton, Jeremy; Riaz, Nadeem; Reis-Filho, Jorge S; Powell, Simon; Knowles, David A; Reznik, Ed; Mishra, Bud; Beroukhim, Rameen; Zody, Michael C; Robine, Nicolas; Oman, Kenji M; Sanchez, Carissa A; Kuhner, Mary K; Smith, Lucian P; Galipeau, Patricia C; Paulson, Thomas G; Reid, Brian J; Li, Xiaohong; Wilkes, David; Sboner, Andrea; Mosquera, Juan Miguel.

Cell ; 183(1): 197-210.e32, 2020 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-33007263

2.

Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers.

Setton, Jeremy; Hadi, Kevin; Choo, Zi-Ning; Kuchin, Katherine S; Tian, Huasong; Da Cruz Paula, Arnaud; Rosiene, Joel; Selenica, Pier; Behr, Julie; Yao, Xiaotong; Deshpande, Aditya; Sigouros, Michael; Manohar, Jyothi; Nauseef, Jones T; Mosquera, Juan-Miguel; Elemento, Olivier; Weigelt, Britta; Riaz, Nadeem; Reis-Filho, Jorge S; Powell, Simon N; Imielinski, Marcin.

Nature ; 621(7977): 129-137, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37587346

3.

Non-cell-autonomous cancer progression from chromosomal instability.

Li, Jun; Hubisz, Melissa J; Earlie, Ethan M; Duran, Mercedes A; Hong, Christy; Varela, Austin A; Lettera, Emanuele; Deyell, Matthew; Tavora, Bernardo; Havel, Jonathan J; Phyu, Su M; Amin, Amit Dipak; Budre, Karolina; Kamiya, Erina; Cavallo, Julie-Ann; Garris, Christopher; Powell, Simon; Reis-Filho, Jorge S; Wen, Hannah; Bettigole, Sarah; Khan, Atif J; Izar, Benjamin; Parkes, Eileen E; Laughney, Ashley M; Bakhoum, Samuel F.

Nature ; 620(7976): 1080-1088, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37612508

4.

Single-cell genomic variation induced by mutational processes in cancer.

Funnell, Tyler; O'Flanagan, Ciara H; Williams, Marc J; McPherson, Andrew; McKinney, Steven; Kabeer, Farhia; Lee, Hakwoo; Salehi, Sohrab; Vázquez-García, Ignacio; Shi, Hongyu; Leventhal, Emily; Masud, Tehmina; Eirew, Peter; Yap, Damian; Zhang, Allen W; Lim, Jamie L P; Wang, Beixi; Brimhall, Jazmine; Biele, Justina; Ting, Jerome; Au, Vinci; Van Vliet, Michael; Liu, Yi Fei; Beatty, Sean; Lai, Daniel; Pham, Jenifer; Grewal, Diljot; Abrams, Douglas; Havasov, Eliyahu; Leung, Samantha; Bojilova, Viktoria; Moore, Richard A; Rusk, Nicole; Uhlitz, Florian; Ceglia, Nicholas; Weiner, Adam C; Zaikova, Elena; Douglas, J Maxwell; Zamarin, Dmitriy; Weigelt, Britta; Kim, Sarah H; Da Cruz Paula, Arnaud; Reis-Filho, Jorge S; Martin, Spencer D; Li, Yangguang; Xu, Hong; de Algara, Teresa Ruiz; Lee, So Ra; Llanos, Viviana Cerda; Huntsman, David G.

Nature ; 612(7938): 106-115, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-36289342

5.

Diverse alterations associated with resistance to KRAS(G12C) inhibition.

Zhao, Yulei; Murciano-Goroff, Yonina R; Xue, Jenny Y; Ang, Agnes; Lucas, Jessica; Mai, Trang T; Da Cruz Paula, Arnaud F; Saiki, Anne Y; Mohn, Deanna; Achanta, Pragathi; Sisk, Ann E; Arora, Kanika S; Roy, Rohan S; Kim, Dongsung; Li, Chuanchuan; Lim, Lee P; Li, Mark; Bahr, Amber; Loomis, Brian R; de Stanchina, Elisa; Reis-Filho, Jorge S; Weigelt, Britta; Berger, Michael; Riely, Gregory; Arbour, Kathryn C; Lipford, J Russell; Li, Bob T; Lito, Piro.

Nature ; 599(7886): 679-683, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34759319

6.

Genetic interactions in cancer progression and treatment.

Ashworth, Alan; Lord, Christopher J; Reis-Filho, Jorge S.

Cell ; 145(1): 30-8, 2011 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-21458666

7.

Standard-of-care systemic therapy with or without stereotactic body radiotherapy in patients with oligoprogressive breast cancer or non-small-cell lung cancer (Consolidative Use of Radiotherapy to Block [CURB] oligoprogression): an open-label, randomised, controlled, phase 2 study.

Tsai, Chiaojung Jillian; Yang, Jonathan T; Shaverdian, Narek; Patel, Juber; Shepherd, Annemarie F; Eng, Juliana; Guttmann, David; Yeh, Randy; Gelblum, Daphna Y; Namakydoust, Azadeh; Preeshagul, Isabel; Modi, Shanu; Seidman, Andrew; Traina, Tiffany; Drullinsky, Pamela; Flynn, Jessica; Zhang, Zhigang; Rimner, Andreas; Gillespie, Erin F; Gomez, Daniel R; Lee, Nancy Y; Berger, Michael; Robson, Mark E; Reis-Filho, Jorge S; Riaz, Nadeem; Rudin, Charles M; Powell, Simon N.

Lancet ; 403(10422): 171-182, 2024 Jan 13.

Artigo em Inglês | MEDLINE | ID: mdl-38104577

8.

Decreased HER2 expression in endometrial cancer following anti-HER2 therapy.

Chui, M Herman; Brown, David N; Da Cruz Paula, Arnaud; da Silva, Edaise M; Momeni-Boroujeni, Amir; Reis-Filho, Jorge S; Zhang, Yanming; Makker, Vicky; Ellenson, Lora Hedrick; Weigelt, Britta.

J Pathol ; 262(2): 129-136, 2024 02.

Artigo em Inglês | MEDLINE | ID: mdl-38013631

9.

Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer.

Jahangir, Chowdhury Arif; Page, David B; Broeckx, Glenn; Gonzalez, Claudia A; Burke, Caoimbhe; Murphy, Clodagh; Reis-Filho, Jorge S; Ly, Amy; Harms, Paul W; Gupta, Rajarsi R; Vieth, Michael; Hida, Akira I; Kahila, Mohamed; Kos, Zuzana; van Diest, Paul J; Verbandt, Sara; Thagaard, Jeppe; Khiroya, Reena; Abduljabbar, Khalid; Acosta Haab, Gabriela; Acs, Balazs; Adams, Sylvia; Almeida, Jonas S; Alvarado-Cabrero, Isabel; Azmoudeh-Ardalan, Farid; Badve, Sunil; Baharun, Nurkhairul Bariyah; Bellolio, Enrique R; Bheemaraju, Vydehi; Blenman, Kim Rm; Botinelly Mendonça Fujimoto, Luciana; Burgues, Octavio; Chardas, Alexandros; Cheang, Maggie Chon U; Ciompi, Francesco; Cooper, Lee Ad; Coosemans, An; Corredor, Germán; Dantas Portela, Flavio Luis; Deman, Frederik; Demaria, Sandra; Dudgeon, Sarah N; Elghazawy, Mahmoud; Fernandez-Martín, Claudio; Fineberg, Susan; Fox, Stephen B; Giltnane, Jennifer M; Gnjatic, Sacha; Gonzalez-Ericsson, Paula I; Grigoriadis, Anita.

J Pathol ; 262(3): 271-288, 2024 03.

Artigo em Inglês | MEDLINE | ID: mdl-38230434

10.

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.

Heidorn, Sonja J; Milagre, Carla; Whittaker, Steven; Nourry, Arnaud; Niculescu-Duvas, Ion; Dhomen, Nathalie; Hussain, Jahan; Reis-Filho, Jorge S; Springer, Caroline J; Pritchard, Catrin; Marais, Richard.

Cell ; 140(2): 209-21, 2010 Jan 22.

Artigo em Inglês | MEDLINE | ID: mdl-20141835

11.

Nonlobular Invasive Breast Carcinomas with Biallelic Pathogenic CDH1 Somatic Alterations: A Histologic, Immunophenotypic, and Genomic Characterization.

Derakhshan, Fatemeh; Da Cruz Paula, Arnaud; Selenica, Pier; da Silva, Edaise M; Grabenstetter, Anne; Jalali, Sahar; Gazzo, Andrea M; Dopeso, Higinio; Marra, Antonio; Brown, David N; Ross, Dara S; Mandelker, Diana; Razavi, Pedram; Chandarlapaty, Sarat; Wen, Hannah Y; Brogi, Edi; Zhang, Hong; Weigelt, Britta; Pareja, Fresia; Reis-Filho, Jorge S.

Mod Pathol ; 37(2): 100375, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-37925055

12.

Adenoid cystic carcinoma of the Bartholin's gland is underpinned by MYB- and MYBL1- rearrangements.

Feinberg, Jacqueline; Da Cruz Paula, Arnaud; da Silva, Edaise M; Pareja, Fresia; Patel, Juber; Zhu, Yingjie; Selenica, Pier; Leitao, Mario M; Abu-Rustum, Nadeem R; Reis-Filho, Jorge S; Joehlin-Price, Amy; Weigelt, Britta.

Gynecol Oncol ; 185: 58-67, 2024 Feb 17.

Artigo em Inglês | MEDLINE | ID: mdl-38368814

13.

NR4A3 Expression Is Consistently Absent in Acinic Cell Carcinomas of the Breast: A Potential Nosologic Shift.

Richardson, Edward T; Selenica, Pier; Pareja, Fresia; Cin, Paola Dal; Hanlon, Etta; Weigelt, Britta; Reis-Filho, Jorge S; Hornick, Jason L; Jo, Vickie Y; Schnitt, Stuart J.

Mod Pathol ; 36(6): 100144, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-36828363

14.

HER2 Genetic Intratumor Heterogeneity Is Associated With Resistance to Trastuzumab and Trastuzumab Emtansine Therapy in Recurrent High-Grade Endometrial Cancer.

Shen, Sherry; Ma, Weining; Brown, David; Da Cruz Paula, Arnaud; Zhou, Qin; Iaosonos, Alexia; Tessier-Cloutier, Basile; Ross, Dara S; Troso-Sandoval, Tiffany; Reis-Filho, Jorge S; Abu-Rustum, Nadeem; Zhang, Yanming; Ellenson, Lora H; Weigelt, Britta; Makker, Vicky; Chui, M Herman.

Mod Pathol ; 36(11): 100299, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37558129

15.

Impact of immune infiltration signatures on prognosis in endometrial carcinoma is dependent on the underlying molecular subtype.

Dessources, Kimberly; Ferrando, Lorenzo; Zhou, Qin C; Iasonos, Alexia; Abu-Rustum, Nadeem R; Reis-Filho, Jorge S; Riaz, Nadeem; Zamarin, Dmitriy; Weigelt, Britta.

Gynecol Oncol ; 171: 15-22, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36804617

16.

Recurrent WWTR1 S89W mutations and Hippo pathway deregulation in clear cell carcinomas of the cervix.

Kim, Sarah H; Basili, Thais; Dopeso, Higinio; Da Cruz Paula, Arnaud; Bi, Rui; Issa Bhaloo, Shirin; Pareja, Fresia; Li, Qing; da Silva, Edaise M; Zhu, Yingjie; Hoang, Timothy; Selenica, Pier; Murali, Rajmohan; Chan, Eric; Wu, Michelle; Derakhshan, Fatemeh; Maroldi, Ana; Hanlon, Etta; Ferreira, Carlos Gil; Lapa E Silva, Jose Roberto; Abu-Rustum, Nadeem R; Zamarin, Dmitriy; Chandarlapaty, Sarat; Matrai, Cathleen; Yoon, Ju-Yoon; Reis-Filho, Jorge S; Park, Kay J; Weigelt, Britta.

J Pathol ; 257(5): 635-649, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35411948

17.

The clinical behavior and genomic features of the so-called adenoid cystic carcinomas of the solid variant with basaloid features.

Schwartz, Christopher J; Brogi, Edi; Marra, Antonio; Da Cruz Paula, Arnaud F; Nanjangud, Gouri J; da Silva, Edaise M; Patil, Sujata; Shah, Shreena; Ventura, Katia; Razavi, Pedram; Norton, Larry; D'alfonso, Timothy; Weigelt, Britta; Pareja, Fresia; Reis-Filho, Jorge S; Wen, Hannah Y.

Mod Pathol ; 35(2): 193-201, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34599282

18.

Pancreatoblastomas and mixed and pure acinar cell carcinomas share epigenetic signatures distinct from other neoplasms of the pancreas.

Benhamida, Jamal K; Vyas, Monika; Tanaka, Atsushi; Wang, Lu; Bahrami, Armita; Ozcan, Kerem; Basturk, Olca; Villafania, Liliana; Mata, Douglas A; El Jabbour, Tony; Selenica, Pier; Roehrl, Michael H A; Weigelt, Britta; Reis-Filho, Jorge S; Scaltriti, Maurizio; Klimstra, David S.

Mod Pathol ; 35(7): 956-961, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-34969956

19.

Hyperthermic intraperitoneal chemotherapy (HIPEC) with carboplatin induces distinct transcriptomic changes in ovarian tumor and normal tissues.

Moukarzel, Lea A; Ferrando, Lorenzo; Dopeso, Higinio; Stylianou, Anthe; Basili, Thais; Pareja, Fresia; Da Cruz Paula, Arnaud; Zoppoli, Gabriele; Abu-Rustum, Nadeem R; Reis-Filho, Jorge S; Long Roche, Kara; Tew, William P; Chi, Dennis S; Sonoda, Yukio; Zamarin, Dmitriy; Aghajanian, Carol; O'Cearbhaill, Roisin E; Zivanovic, Oliver; Weigelt, Britta.

Gynecol Oncol ; 165(2): 239-247, 2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-35292180

20.

Independent real-world application of a clinical-grade automated prostate cancer detection system.

da Silva, Leonard M; Pereira, Emilio M; Salles, Paulo Go; Godrich, Ran; Ceballos, Rodrigo; Kunz, Jeremy D; Casson, Adam; Viret, Julian; Chandarlapaty, Sarat; Ferreira, Carlos Gil; Ferrari, Bruno; Rothrock, Brandon; Raciti, Patricia; Reuter, Victor; Dogdas, Belma; DeMuth, George; Sue, Jillian; Kanan, Christopher; Grady, Leo; Fuchs, Thomas J; Reis-Filho, Jorge S.

J Pathol ; 254(2): 147-158, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-33904171

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