Detalhe da pesquisa
1.
An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells.
Cell
; 182(4): 1009-1026.e29, 2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32730809
2.
Chemical Proteomic Discovery of Isotype-Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2.
Angew Chem Int Ed Engl
; 62(51): e202311924, 2023 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37909922
3.
Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1.
J Am Chem Soc
; 144(40): 18688-18699, 2022 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36170674
4.
Correction to "Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1".
J Am Chem Soc
; 145(23): 12948, 2023 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37268298
5.
Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.
Angew Chem Int Ed Engl
; 56(21): 5738-5743, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28418626
6.
Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities.
Nat Struct Mol Biol
; 30(8): 1160-1171, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37488358
7.
A novel ß-catenin/BCL9 complex inhibitor blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer.
Sci Adv
; 8(17): eabm3108, 2022 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35486727
8.
Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8.
ACS Chem Biol
; 16(11): 2185-2192, 2021 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34515462
9.
Dual Inhibition of TAF1 and BET Bromodomains from the BI-2536 Kinase Inhibitor Scaffold.
ACS Med Chem Lett
; 10(10): 1443-1449, 2019 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31620231
10.
A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.
Nat Cell Biol
; 20(12): 1410-1420, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30397315
11.
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma.
Elife
; 72018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30431433
12.
Cannabis Roots: A Traditional Therapy with Future Potential for Treating Inflammation and Pain.
Cannabis Cannabinoid Res
; 2(1): 210-216, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29082318
13.
Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET-BRET.
ChemMedChem
; 11(23): 2575-2581, 2016 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27862999