Detalhe da pesquisa
1.
Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases.
J Biol Chem
; 296: 100101, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33214225
2.
The discovery and maturation of peptide biologics targeting the small G-protein Cdc42: A bioblockade for Ras-driven signaling.
J Biol Chem
; 295(9): 2866-2884, 2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31959628
3.
Is more better? A comparison of tri- and tetrapeptidic catalysts.
Org Biomol Chem
; 15(28): 5877-5881, 2017 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28590473
4.
Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency.
Nat Chem
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38755312
5.
Systems Biology and Peptide Engineering to Overcome Absorption Barriers for Oral Peptide Delivery: Dosage Form Optimization Case Study Preceding Clinical Translation.
Pharmaceutics
; 15(10)2023 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37896196
6.
Targeted oral peptide delivery using multi-unit particulates: Drug and permeation enhancer layering approach.
J Control Release
; 338: 784-791, 2021 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34499981
7.
Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease.
Sci Rep
; 11(1): 22521, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34795324
8.
Peptide catalyzed asymmetric conjugate addition reactions of aldehydes to nitroethylene--a convenient entry into gamma2-amino acids.
J Am Chem Soc
; 130(17): 5610-1, 2008 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-18386927
9.
Peptidic catalysts developed by combinatorial screening methods.
Curr Opin Chem Biol
; 11(3): 269-78, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17548237
10.
TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.
EMBO Mol Med
; 9(10): 1366-1378, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28855301
11.
Increased structural complexity leads to higher activity: peptides as efficient and versatile catalysts for asymmetric aldol reactions.
Org Lett
; 7(6): 1101-3, 2005 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-15760149
12.
PS-COD and PS-9-BBN: polymer-supported reagents for solution-phase parallel synthesis.
Org Lett
; 7(5): 831-3, 2005 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-15727452
13.
Ionic liquid acceleration of solid-phase suzuki-miyaura cross-coupling reactions.
Org Lett
; 4(18): 3071-3, 2002 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12201719
14.
A 'triflate-like' tetrafluoroarylsulfonate linker for multifunctional solid-phase organic synthesis.
Chem Commun (Camb)
; (17): 1916-7, 2004 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15340599
15.
Tripeptides as efficient asymmetric catalysts for 1,4-addition reactions of aldehydes to nitroolefins--a rational approach.
Angew Chem Int Ed Engl
; 47(10): 1871-4, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18228232
16.
Recombinant expression and in vitro characterisation of active Huwentoxin-IV.
PLoS One
; 8(12): e83202, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24324842
17.
Potency optimization of Huwentoxin-IV on hNav1.7: a neurotoxin TTX-S sodium-channel antagonist from the venom of the Chinese bird-eating spider Selenocosmia huwena.
Peptides
; 44: 40-6, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23523779
18.
Stapled Vasoactive Intestinal Peptide (VIP) Derivatives Improve VPAC2 Agonism and Glucose-Dependent Insulin Secretion.
ACS Med Chem Lett
; 4(12): 1163-8, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900623
19.
Separating stereoisomers of di-, tri-, and tetrapeptides using capillary electrophoresis with contactless conductivity detection.
J Sep Sci
; 31(3): 565-73, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18210379
20.
Solid-supported and pegylated H-Pro-Pro-Asp-NHR as catalysts for asymmetric aldol reactions.
Biopolymers
; 84(1): 105-13, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16245260