Detalhe da pesquisa
1.
The Novel Phosphodiesterase 9A Inhibitor BI 409306 Increases Cyclic Guanosine Monophosphate Levels in the Brain, Promotes Synaptic Plasticity, and Enhances Memory Function in Rodents.
J Pharmacol Exp Ther
; 371(3): 633-641, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578258
2.
K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation.
EMBO J
; 33(17): 1912-27, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25024434
3.
Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-ß.
Nature
; 485(7400): 651-5, 2012 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22660329
4.
Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc.
Proc Natl Acad Sci U S A
; 110(2): 648-53, 2013 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23267072
5.
Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal Neurons.
Neural Plast
; 2016: 4145708, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26881108
6.
Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy.
Kidney Int
; 87(1): 74-84, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25075770
7.
Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke.
Acta Neuropathol
; 129(2): 259-77, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25391494
8.
Molecular basis of ß-amyloid oligomer recognition with a conformational antibody fragment.
Proc Natl Acad Sci U S A
; 109(31): 12503-8, 2012 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22814377
9.
SPECT-imaging of activity-dependent changes in regional cerebral blood flow induced by electrical and optogenetic self-stimulation in mice.
Neuroimage
; 103: 171-180, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25234116
10.
Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity.
Proc Natl Acad Sci U S A
; 107(5): 1942-7, 2010 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20133839
11.
Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aß is induced by pyroglutamate-Aß formation.
J Neurosci
; 31(36): 12790-801, 2011 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21900558
12.
N-Terminal pyroglutamate formation of Aß38 and Aß40 enforces oligomer formation and potency to disrupt hippocampal long-term potentiation.
J Neurochem
; 121(5): 774-84, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22375951
13.
Insufficient endogenous redox buffer capacity may underlie neuronal vulnerability to cerebral ischemia and reperfusion.
J Neurosci Res
; 90(1): 193-202, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21971686
14.
Do basophile structures as age dependent phenomenon indicate small vessel wall damage?
Microvasc Res
; 84(3): 375-7, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22902586
15.
A population of serum deprivation-induced bone marrow stem cells (SD-BMSC) expresses marker typical for embryonic and neural stem cells.
Exp Cell Res
; 315(1): 50-66, 2009 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18992240
16.
Microglia cells protect neurons by direct engulfment of invading neutrophil granulocytes: a new mechanism of CNS immune privilege.
J Neurosci
; 28(23): 5965-75, 2008 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18524901
17.
Neuroprotection and enhanced neurogenesis by extract from the tropical plant Knema laurina after inflammatory damage in living brain tissue.
J Neuroimmunol
; 206(1-2): 91-9, 2009 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19028400
18.
Time-dependent segmentation of BrdU-signal leads to late detection problems in studies using BrdU as cell label or proliferation marker.
J Neurosci Methods
; 177(1): 149-59, 2009 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19007815
19.
Inhibition of Calpain Prevents N-Methyl-D-aspartate-Induced Degeneration of the Nucleus Basalis and Associated Behavioral Dysfunction.
J Pharmacol Exp Ther
; 327(2): 343-52, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18701765
20.
The novel selective PDE9 inhibitor BAY 73-6691 improves learning and memory in rodents.
Neuropharmacology
; 55(5): 908-18, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18674549