Detalhe da pesquisa
1.
An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.
Mol Cell
; 63(3): 485-97, 2016 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27425408
2.
Small-molecule allosteric inhibitors of BAX.
Nat Chem Biol
; 15(4): 322-330, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718816
3.
An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.
Mol Cell
; 64(2): 431, 2016 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27768876
4.
BH3-triggered structural reorganization drives the activation of proapoptotic BAX.
Mol Cell
; 40(3): 481-92, 2010 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21070973
5.
Bax regulates primary necrosis through mitochondrial dynamics.
Proc Natl Acad Sci U S A
; 109(17): 6566-71, 2012 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22493254
6.
Direct and selective small-molecule activation of proapoptotic BAX.
Nat Chem Biol
; 8(7): 639-45, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22634637
7.
Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer.
Nat Commun
; 13(1): 1199, 2022 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35256598
8.
Eltrombopag directly inhibits BAX and prevents cell death.
Nat Commun
; 12(1): 1134, 2021 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33602934
9.
Apoptosis signaling molecules as treatment targets in head and neck squamous cell carcinoma.
Laryngoscope
; 130(11): 2643-2649, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31894587
10.
Liposomal Permeabilization Assay to Study the Functional Interactions of the BCL-2 Family.
Methods Mol Biol
; 1877: 111-119, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30536001
11.
Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment.
Cancer Discov
; 9(7): 890-909, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31048321
12.
Optimal targeting of BCL-family proteins in head and neck squamous cell carcinoma requires inhibition of both BCL-xL and MCL-1.
Oncotarget
; 10(4): 494-510, 2019 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30728900
13.
Progress in targeting the BCL-2 family of proteins.
Curr Opin Chem Biol
; 39: 133-142, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28735187
14.
Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia.
Cancer Cell
; 32(4): 490-505.e10, 2017 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29017059
15.
In Response to Regarding: Apoptosis Signaling Molecules as Treatment Targets in Head and Neck Squamous Carcinoma.
Laryngoscope
; 130(8): E458-E459, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32421206
16.
An interconnected hierarchical model of cell death regulation by the BCL-2 family.
Nat Cell Biol
; 17(10): 1270-81, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26344567
17.
Pulling the BAX trigger for tumor cell death.
Oncotarget
; 9(9): 8204-8205, 2018 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29492188
18.
Self-regulation of BAX-induced cell death.
Oncotarget
; 7(41): 66326-66327, 2016 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27626173