Detalhe da pesquisa
1.
Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.
Proc Natl Acad Sci U S A
; 115(5): E886-E895, 2018 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29339518
2.
The protofilament architecture of a de novo designed coiled coil-based amyloidogenic peptide.
J Struct Biol
; 203(3): 263-272, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29857134
3.
Investigation of the network of preferred interactions in an artificial coiled-coil association using the peptide array technique.
Beilstein J Org Chem
; 8: 640-9, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22563362
4.
A systematic study of fundamentals in α-helical coiled coil mimicry by alternating sequences of ß- and γ-amino acids.
Amino Acids
; 41(3): 733-42, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21638022
5.
Intramolecular charge interactions as a tool to control the coiled-coil-to-amyloid transformation.
Chemistry
; 14(36): 11442-51, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-19016556
6.
Designing helical peptide inhibitors of protein-protein interactions.
Curr Opin Struct Biol
; 39: 27-38, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27123812
7.
Rapid Optimization of Mcl-1 Inhibitors using Stapled Peptide Libraries Including Non-Natural Side Chains.
ACS Chem Biol
; 11(5): 1238-44, 2016 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26854535
8.
A beta/gamma motif to mimic alpha-helical turns in proteins.
Chembiochem
; 11(3): 335-9, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20039254
9.
An unusual interstrand H-bond stabilizes the heteroassembly of helical αßγ-chimeras with natural peptides.
ACS Chem Biol
; 9(3): 613-6, 2014 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24341921
10.
ß- and γ-Amino Acids at α-Helical Interfaces: Toward the Formation of Highly Stable Foldameric Coiled Coils.
ACS Med Chem Lett
; 5(12): 1300-3, 2014 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25516788