Detalhe da pesquisa
1.
Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer.
Int J Mol Sci
; 18(10)2017 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29039788
2.
The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanisms.
BMC Cancer
; 16: 49, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26833217
3.
Dual-Luciferase Reporter Assay for Prescreening CRISPR (d)Cas9-Mediated Epigenetic Editing on a Plant Promoter Using Human Cells.
Methods Mol Biol
; 2788: 273-285, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38656520
4.
Biomarker RIPK3 Is Silenced by Hypermethylation in Melanoma and Epigenetic Editing Reestablishes Its Tumor Suppressor Function.
Genes (Basel)
; 15(2)2024 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38397165
5.
Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner.
Cancer Gene Ther
; 29(12): 1975-1987, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35902728
6.
The RASSF proteins in cancer; from epigenetic silencing to functional characterization.
Biochim Biophys Acta
; 1796(2): 114-28, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19344752
7.
Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences.
Mol Cancer
; 9: 264, 2010 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20920251
8.
The ZAR1 protein in cancer; from epigenetic silencing to functional characterisation and epigenetic therapy of tumour suppressors.
Biochim Biophys Acta Rev Cancer
; 1874(2): 188417, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32828887
9.
RASSF10 is frequently epigenetically inactivated in kidney cancer and its knockout promotes neoplasia in cancer prone mice.
Oncogene
; 39(15): 3114-3127, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32047266
10.
Epigenetic Inactivation of the Tumor Suppressor IRX1 Occurs Frequently in Lung Adenocarcinoma and Its Silencing Is Associated with Impaired Prognosis.
Cancers (Basel)
; 12(12)2020 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33256112
11.
RASSF10 Is a TGFß-Target That Regulates ASPP2 and E-Cadherin Expression and Acts as Tumor Suppressor That Is Epigenetically Downregulated in Advanced Cancer.
Cancers (Basel)
; 11(12)2019 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31817988
12.
Epigenetic therapy of novel tumour suppressor ZAR1 and its cancer biomarker function.
Clin Epigenetics
; 11(1): 182, 2019 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31801617
13.
The tumor suppressor RASSF1A induces the YAP1 target gene ANKRD1 that is epigenetically inactivated in human cancers and inhibits tumor growth.
Oncotarget
; 8(51): 88437-88452, 2017 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29179447
14.
ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer.
Clin Epigenetics
; 9: 60, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28588743
15.
Aberrant Promoter Methylation of the Tumour Suppressor RASSF10 and Its Growth Inhibitory Function in Breast Cancer.
Cancers (Basel)
; 8(3)2016 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26927176
16.
Claudin11 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin, but Uncommon in Nevus Cell Nevi.
Cancers (Basel)
; 7(3): 1233-43, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26198249
17.
Promoter methylation status of Ras-association domain family members in pheochromocytoma.
Front Endocrinol (Lausanne)
; 6: 21, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25750636
18.
The apoptosis associated tyrosine kinase gene is frequently hypermethylated in human cancer and is regulated by epigenetic mechanisms.
Genes Cancer
; 5(9-10): 365-74, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25352953
19.
ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth.
Sci Rep
; 4: 6899, 2014 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25367630
20.
Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma.
Cancers (Basel)
; 5(4): 1566-76, 2013 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24252868