Detalhe da pesquisa
1.
Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer's disease reveals distinct sequential responses to Aß and tau.
Acta Neuropathol
; 147(1): 65, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38557897
2.
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.
Nature
; 541(7635): 81-86, 2017 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28002404
3.
Seventy-five genetic loci influencing the human red blood cell.
Nature
; 492(7429): 369-75, 2012 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23222517
4.
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.
PLoS Genet
; 11(7): e1005230, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26132169
5.
A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.
J Lipid Res
; 58(9): 1834-1844, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28512139
6.
Human metabolic individuality in biomedical and pharmaceutical research.
Nature
; 477(7362): 54-60, 2011 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-21886157
7.
Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses.
Hum Mol Genet
; 23(21): 5847-57, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24927737
8.
Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels.
PLoS Genet
; 9(8): e1003585, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23990791
9.
Harmonization of study and reference data by PhaseLift: saving time when imputing study data.
Genet Epidemiol
; 38(5): 381-8, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24962562
10.
Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.
Hum Genet
; 134(2): 131-46, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25367360
11.
Discovery of sexual dimorphisms in metabolic and genetic biomarkers.
PLoS Genet
; 7(8): e1002215, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21852955
12.
A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.
PLoS Genet
; 7(10): e1002333, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22028671
13.
Establishment of a high-content imaging assay for tau aggregation in hiPSC-derived neurons differentiated from two protocols to routinely evaluate compounds and genetic perturbations.
SLAS Discov
; 29(2): 100137, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38128829
14.
PSEA: Phenotype Set Enrichment Analysis--a new method for analysis of multiple phenotypes.
Genet Epidemiol
; 36(3): 244-52, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22714936
15.
The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.
PLoS Med
; 10(6): e1001474, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23824655
16.
Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.
Hum Mol Genet
; 20(5): 1042-7, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21149283
17.
Rare exonic deletions of the RBFOX1 gene increase risk of idiopathic generalized epilepsy.
Epilepsia
; 54(2): 265-71, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23350840
18.
Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.
PLoS Genet
; 6(11): e1001213, 2010 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21124955
19.
Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.
PLoS Genet
; 6(8)2010 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20700443
20.
Common genetic variants associate with serum phosphorus concentration.
J Am Soc Nephrol
; 21(7): 1223-32, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20558539