Detalhe da pesquisa
1.
Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding.
Nucleic Acids Res
; 52(5): 2355-2371, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38180815
2.
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase.
Nucleic Acids Res
; 51(4): 1783-1802, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36762474
3.
Control of backbone chemistry and chirality boost oligonucleotide splice switching activity.
Nucleic Acids Res
; 50(10): 5443-5466, 2022 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35061895
5.
AR cooperates with SMAD4 to maintain skeletal muscle homeostasis.
Acta Neuropathol
; 143(6): 713-731, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35522298
6.
MicroRNA-298 reduces levels of human amyloid-ß precursor protein (APP), ß-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties.
Mol Psychiatry
; 26(10): 5636-5657, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31942037
7.
DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends.
Nucleic Acids Res
; 48(5): 2424-2441, 2020 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31879780
8.
A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy.
Hum Mol Genet
; 25(10): 1979-1989, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26962150
9.
Beyond motor neurons: expanding the clinical spectrum in Kennedy's disease.
J Neurol Neurosurg Psychiatry
; 89(8): 808-812, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29353237
10.
MiR-298 Counteracts Mutant Androgen Receptor Toxicity in Spinal and Bulbar Muscular Atrophy.
Mol Ther
; 24(5): 937-45, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26755334
11.
Cowchock syndrome is associated with a mutation in apoptosis-inducing factor.
Am J Hum Genet
; 91(6): 1095-102, 2012 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23217327
12.
Plasma pNfH levels differentiate SBMA from ALS.
J Neurol Neurosurg Psychiatry
; 91(2): 215-217, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31575607
13.
Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients.
Neurobiol Dis
; 70: 12-20, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24925468
14.
Hereditary spastic paraplegia type 43 (SPG43) is caused by mutation in C19orf12.
Hum Mutat
; 34(10): 1357-60, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23857908
15.
RNA Transcript Diversity in Neuromuscular Research.
J Neuromuscul Dis
; 10(4): 473-482, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37182892
16.
The multistep path to replicative senescence onset: zooming on triggering and inhibitory events at telomeric DNA.
Front Cell Dev Biol
; 11: 1250264, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37771378
17.
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation.
Cell Rep
; 42(11): 113360, 2023 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38007689
18.
A modular RNA delivery system comprising spherical nucleic acids built on endosome-escaping polymeric nanoparticles.
Nanoscale Adv
; 5(11): 2941-2949, 2023 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37260495
19.
PRMT inhibitor promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue SMA mice.
EMBO Mol Med
; 15(11): e17683, 2023 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37724723
20.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.
Nat Commun
; 14(1): 603, 2023 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36746939