Detalhe da pesquisa
1.
Clinical and genomic characterization of patients diagnosed with the provisional entity acute myeloid leukemia with BCR-ABL1, a Swedish population-based study.
Genes Chromosomes Cancer
; 60(6): 426-433, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33433047
2.
A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells.
Haematologica
; 105(8): 2095-2104, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31582541
3.
Genetic profiling of a chondroblastoma-like osteosarcoma/malignant phosphaturic mesenchymal tumor of bone reveals a homozygous deletion of CDKN2A, intragenic deletion of DMD, and a targetable FN1-FGFR1 gene fusion.
Genes Chromosomes Cancer
; 58(10): 731-736, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31066955
4.
IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models.
Blood
; 128(23): 2683-2693, 2016 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27621309
5.
IL1RAP is expressed in several subtypes of pediatric acute lymphoblastic leukemia and can be used as a target to eliminate ETV6::RUNX1-positive leukemia cells in preclinical models.
Haematologica
; 108(2): 599-604, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36226493
6.
CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting.
Haematologica
; 103(3): 447-455, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29284680
7.
Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
Proc Natl Acad Sci U S A
; 112(34): 10786-91, 2015 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26261316
8.
Primary cells in BCR/FGFR1-positive 8p11 myeloproliferative syndrome are sensitive to dovitinib, ponatinib, and dasatinib.
Eur J Haematol
; 99(5): 442-448, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28881484
9.
Isolated myelosarcoma is characterized by recurrent NFE2 mutations and concurrent preleukemic clones in the bone marrow.
Blood
; 131(5): 577-581, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29191917
10.
Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.
Blood
; 121(18): 3709-13, 2013 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23479569
11.
Smad4 binds Hoxa9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by Hoxa9 and leukemia transformation.
Blood
; 117(22): 5918-30, 2011 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21471525
12.
Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.
Proc Natl Acad Sci U S A
; 107(37): 16280-5, 2010 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20805474
13.
The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML.
Blood Adv
; 7(7): 1204-1218, 2023 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36383712
14.
Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice.
Blood
; 116(12): 2103-11, 2010 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20554971
15.
Clonal competition within complex evolutionary hierarchies shapes AML over time.
Nat Commun
; 11(1): 579, 2020 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32024830
16.
Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia.
Leukemia
; 32(10): 2117-2125, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29626196
17.
Transgenic expression of human cytokines in immunodeficient mice does not facilitate myeloid expansion of BCR-ABL1 transduced human cord blood cells.
PLoS One
; 12(10): e0186035, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29023488
18.
Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.
Nat Commun
; 7: 11790, 2016 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27265895
19.
The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
Nat Genet
; 47(6): 672-6, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25961940
20.
Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney.
Cancer Lett
; 357(2): 498-501, 2015 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25481751