Detalhe da pesquisa
1.
ß-Secretase BACE1 regulates hippocampal and reconstituted M-currents in a ß-subunit-like fashion.
J Neurosci
; 35(8): 3298-311, 2015 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25716831
2.
BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs).
J Mol Cell Cardiol
; 89(Pt B): 335-48, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26454161
3.
Lysosomal integral membrane protein type-2 (LIMP-2/SCARB2) is a substrate of cathepsin-F, a cysteine protease mutated in type-B-Kufs-disease.
Biochem Biophys Res Commun
; 457(3): 334-40, 2015 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25576872
4.
TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death.
Cell Mol Life Sci
; 71(2): 331-48, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23760205
5.
Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice.
Gut
; 62(4): 520-30, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22442160
6.
Physiological functions of the amyloid precursor protein secretases ADAM10, BACE1, and presenilin.
Exp Brain Res
; 217(3-4): 331-41, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22120156
7.
Tumor necrosis factor-alpha (TNF-alpha) regulates shedding of TNF-alpha receptor 1 by the metalloprotease-disintegrin ADAM8: evidence for a protease-regulated feedback loop in neuroprotection.
J Neurosci
; 30(36): 12210-8, 2010 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20826683
8.
ß-Site APP-cleaving enzyme 1 (BACE1) cleaves cerebellar Na+ channel ß4-subunit and promotes Purkinje cell firing by slowing the decay of resurgent Na+ current.
Pflugers Arch
; 461(3): 355-71, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21246381
9.
Non-proteolytic effect of beta-site APP-cleaving enzyme 1 (BACE1) on sodium channel function.
Neurobiol Dis
; 33(2): 282-9, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19056495
10.
Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression.
Obesity (Silver Spring)
; 21(12): E626-33, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23596049
11.
Regulated expression of ADAM8 (a disintegrin and metalloprotease domain 8) in the mouse ovary: evidence for a regulatory role of luteinizing hormone, progesterone receptor, and epidermal growth factor-like growth factors.
Biol Reprod
; 78(6): 1038-48, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18287572
12.
Control of peripheral nerve myelination by the beta-secretase BACE1.
Science
; 314(5799): 664-6, 2006 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16990514
13.
Metalloprotease-disintegrin ADAM8: expression analysis and targeted deletion in mice.
Dev Dyn
; 232(1): 221-31, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15580619