Detalhe da pesquisa
1.
Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity.
Nat Immunol
; 24(2): 267-279, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36543958
2.
Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion.
Nat Immunol
; 22(2): 205-215, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33398183
3.
Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance.
Immunity
; 51(3): 548-560.e4, 2019 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31471106
4.
The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis.
PLoS Biol
; 14(7): e1002507, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27389535
5.
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
Proc Natl Acad Sci U S A
; 112(28): 8638-43, 2015 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26124089
6.
An oncolytic virus-delivered TGFß inhibitor overcomes the immunosuppressive tumor microenvironment.
J Exp Med
; 220(10)2023 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37552475
7.
Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma.
Clin Cancer Res
; 29(1): 154-164, 2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36166093
8.
RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage.
Gastroenterology
; 141(4): 1439-50, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21704587
9.
Association of RB/p16-pathway perturbations with DCIS recurrence: dependence on tumor versus tissue microenvironment.
Am J Pathol
; 179(3): 1171-8, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21756866
10.
Fully murine CD105-targeted CAR-T cells provide an immunocompetent model for CAR-T cell biology.
Oncoimmunology
; 11(1): 2131229, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36275862
11.
Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells.
Gastroenterology
; 138(5): 1920-30, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20100483
12.
Antitumor T-cell Reconditioning: Improving Metabolic Fitness for Optimal Cancer Immunotherapy.
Clin Cancer Res
; 24(11): 2473-2481, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29386217
13.
4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses.
J Exp Med
; 215(4): 1091-1100, 2018 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29511066
14.
Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer.
J Clin Invest
; 127(10): 3755-3769, 2017 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28891816
15.
Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion.
Sci Signal
; 8(389): ra80, 2015 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26268608
16.
CDK4/6 inhibition antagonizes the cytotoxic response to anthracycline therapy.
Cell Cycle
; 11(14): 2747-55, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22751436
17.
Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells.
Cell Cycle
; 9(16): 3256-76, 2010 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20814239