Detalhe da pesquisa
1.
Genomic Approaches to Antifungal Drug Target Identification and Validation.
Annu Rev Microbiol
; 76: 369-388, 2022 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35650665
2.
Advancements and challenges in antifungal therapeutic development.
Clin Microbiol Rev
; 37(1): e0014223, 2024 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38294218
3.
A functionally divergent intrinsically disordered region underlying the conservation of stochastic signaling.
PLoS Genet
; 17(9): e1009629, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34506483
4.
Evaluating the scope of rural general surgery in British Columbia.
Can J Surg
; 67(2): E91-E98, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38453349
5.
Bacterial-fungal interactions and their impact on microbial pathogenesis.
Mol Ecol
; 32(10): 2565-2581, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35231147
6.
Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond.
Chem Rev
; 121(6): 3390-3411, 2021 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32441527
7.
Expanding pediatric services to include adults during the COVID-19 pandemic.
J Pediatr Nurs
; 68: 68-73, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36707148
8.
Molecular Evolution of Antifungal Drug Resistance.
Annu Rev Microbiol
; 71: 753-775, 2017 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28886681
9.
Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway.
PLoS Biol
; 17(3): e2006966, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30865631
10.
Functional divergence of a global regulatory complex governing fungal filamentation.
PLoS Genet
; 15(1): e1007901, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30615616
11.
Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs.
PLoS Genet
; 14(4): e1007319, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29702647
12.
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space.
PLoS Genet
; 14(3): e1007270, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29590106
13.
Functional Genomic Analysis of Candida albicans Adherence Reveals a Key Role for the Arp2/3 Complex in Cell Wall Remodelling and Biofilm Formation.
PLoS Genet
; 12(11): e1006452, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27870871
14.
Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues.
PLoS Genet
; 12(10): e1006405, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27788136
15.
Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis.
PLoS Genet
; 12(10): e1006350, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27695031
16.
Extensive functional redundancy in the regulation of Candida albicans drug resistance and morphogenesis by lysine deacetylases Hos2, Hda1, Rpd3 and Rpd31.
Mol Microbiol
; 103(4): 635-656, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27868254
17.
Regulation of the heat shock transcription factor Hsf1 in fungi: implications for temperature-dependent virulence traits.
FEMS Yeast Res
; 18(5)2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29788061
18.
Interdisciplinary approaches for the discovery of novel antifungals.
Trends Mol Med
; 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38777733
19.
A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen Candida albicans.
Microbiol Spectr
; 12(4): e0409523, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38376363
20.
Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-ß-thiophenylacrylamides exerts highly selective antifungal activity.
Cell Chem Biol
; 31(4): 760-775.e17, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38402621