Detalhe da pesquisa
1.
The nematode (Ascaris suum) intestine is a location of synergistic anthelmintic effects of Cry5B and levamisole.
PLoS Pathog
; 20(5): e1011835, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38758969
2.
Nodulisporic acid produces direct activation and positive allosteric modulation of AVR-14B, a glutamate-gated chloride channel from adult Brugia malayi.
Proc Natl Acad Sci U S A
; 119(34): e2111932119, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35969762
3.
Diethylcarbamazine elicits Ca2+ signals through TRP-2 channels that are potentiated by emodepside in Brugia malayi muscles.
Antimicrob Agents Chemother
; 67(10): e0041923, 2023 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37728916
4.
EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor.
PLoS Pathog
; 16(4): e1008396, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32243475
5.
Re-analysis of genomic data: An overview of the mechanisms and complexities of clinical adoption.
Genet Med
; 24(4): 798-810, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35065883
6.
Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content.
BMC Cancer
; 22(1): 85, 2022 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35057759
7.
Combining monoamine oxidase B and semicarbazide-sensitive amine oxidase enzyme inhibition to address inflammatory disease.
Bioorg Med Chem Lett
; 74: 128942, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35973549
8.
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
Nature
; 538(7626): 477-482, 2016 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27760111
9.
Genomic analyses identify molecular subtypes of pancreatic cancer.
Nature
; 531(7592): 47-52, 2016 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26909576
10.
Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel.
PLoS Pathog
; 15(9): e1008041, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31553770
11.
Whole genomes redefine the mutational landscape of pancreatic cancer.
Nature
; 518(7540): 495-501, 2015 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25719666
12.
p38α Regulates Expression of DUX4 in a Model of Facioscapulohumeral Muscular Dystrophy.
J Pharmacol Exp Ther
; 374(3): 489-498, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32576599
13.
Functional genomics in Brugia malayi reveal diverse muscle nAChRs and differences between cholinergic anthelmintics.
Proc Natl Acad Sci U S A
; 114(21): 5539-5544, 2017 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28487481
14.
sCNAphase: using haplotype resolved read depth to genotype somatic copy number alterations from low cellularity aneuploid tumors.
Nucleic Acids Res
; 45(5): e34, 2017 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27903916
15.
Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects.
J Pharmacol Exp Ther
; 358(1): 125-37, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27189974
16.
Functional characterization of a novel family of acetylcholine-gated chloride channels in Schistosoma mansoni.
PLoS Pathog
; 10(6): e1004181, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24945827
17.
Investigation of acetylcholine receptor diversity in a nematode parasite leads to characterization of tribendimidine- and derquantel-sensitive nAChRs.
PLoS Pathog
; 10(1): e1003870, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24497826
18.
Interaction of carvacrol with the Ascaris suum nicotinic acetylcholine receptors and gamma-aminobutyric acid receptors, potential mechanism of antinematodal action.
Parasitol Res
; 114(8): 3059-68, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25944741
19.
Clinically significant changes in genes and variants associated with epilepsy over time: implications for re-analysis.
Sci Rep
; 14(1): 7717, 2024 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38565608
20.
Reanalysis of genomic data in rare disease: current practice and attitudes among Australian clinical and laboratory genetics services.
Eur J Hum Genet
; 2024 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38796577