Detalhe da pesquisa
1.
Neurobehavioral and Cardiovascular Effects of Potassium Cyanide Administered Orally to Mice.
Int J Toxicol
; 35(5): 604-15, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27170681
2.
MMB4 DMS: cardiovascular and pulmonary effects on dogs and neurobehavioral effects on rats.
Int J Toxicol
; 32(4 Suppl): 49S-58S, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23929450
3.
Comparing the sensitivity of cross-over and parallel study designs for QTc assessment: An analysis based on a single large study of moxifloxacin in 48 nonhuman primates.
J Pharmacol Toxicol Methods
; 123: 107299, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37495163
4.
The "One-Step" approach for QT analysis increases the sensitivity of nonclinical QTc analysis.
Clin Transl Sci
; 16(11): 2253-2264, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37726963
5.
Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&As.
J Pharmacol Toxicol Methods
; 123: 107270, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37164235
6.
Chronic xanthine oxidase inhibition following myocardial infarction in rabbits: effects of early versus delayed treatment.
Life Sci
; 82(9-10): 495-502, 2008 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18215719
7.
A canine model of sustained atrial fibrillation induced by rapid atrial pacing and phenylephrine.
Comp Med
; 58(5): 490-3, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19004376
8.
Integration of cardiac energetics, function and histology from isolated rat hearts perfused with doxorubicin and doxorubicin-ol; a model for use in drug safety evaluations.
J Pharmacol Toxicol Methods
; 94(Pt 2): 54-63, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30195582
9.
Use of a failing rabbit heart as a model to predict torsadogenicity.
Toxicol Sci
; 93(1): 205-12, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16740615
10.
Relationship between prolongation of QTc and prolongation of the peak of T (Tp) to the end of T (Te).
J Pharmacol Toxicol Methods
; 52(1): 178-81, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15932797
11.
Evaluation of the six-minute walk test in dogs.
Am J Vet Res
; 65(3): 311-3, 2004 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15027678
12.
Changes in concentrations of neuroendocrine hormones and catecholamines in dogs with myocardial failure induced by rapid ventricular pacing.
Am J Vet Res
; 63(10): 1413-7, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12371769
13.
Effects of tyrosine kinase inhibitors on rat isolated heart function and protein biomarkers indicative of toxicity.
J Pharmacol Toxicol Methods
; 68(1): 150-9, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23660125
14.
Effects of sarcolemmal Ca(2+) entry, ryanodine function, and kinase inhibitors on a rabbit model of heart failure.
Int Heart J
; 51(4): 285-90, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20716847