Detalhe da pesquisa
1.
Combined GS-4774 and Tenofovir Therapy Can Improve HBV-Specific T-Cell Responses in Patients With Chronic Hepatitis.
Gastroenterology
; 157(1): 227-241.e7, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30930022
2.
Randomized phase II study of GS-4774 as a therapeutic vaccine in virally suppressed patients with chronic hepatitis B.
J Hepatol
; 65(3): 509-16, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27210427
3.
Identification and characterization of a cytotoxic T-lymphocyte agonist epitope of brachyury, a transcription factor involved in epithelial to mesenchymal transition and metastasis.
Cancer Immunol Immunother
; 63(12): 1307-17, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25186612
4.
A Phase 2 Randomized Placebo-Controlled Adjuvant Trial of GI-4000, a Recombinant Yeast Expressing Mutated RAS Proteins in Patients with Resected Pancreas Cancer.
J Pancreat Cancer
; 7(1): 8-19, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33786412
5.
Whole Recombinant Saccharomyces cerevisiae Yeast Expressing Ras Mutations as Treatment for Patients With Solid Tumors Bearing Ras Mutations: Results From a Phase 1 Trial.
J Immunother
; 41(3): 141-150, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29528991
6.
GI-19007, a Novel Saccharomyces cerevisiae-Based Therapeutic Vaccine against Tuberculosis.
Clin Vaccine Immunol
; 24(12)2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29046306
7.
Mutation-selective tumor remission with Ras-targeted, whole yeast-based immunotherapy.
Cancer Res
; 64(15): 5084-8, 2004 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15289309
8.
Construction and Immunogenicity Testing of Whole Recombinant Yeast-Based T-Cell Vaccines.
Methods Mol Biol
; 1404: 529-545, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27076321
9.
Phase I Trial of a Yeast-Based Therapeutic Cancer Vaccine (GI-6301) Targeting the Transcription Factor Brachyury.
Cancer Immunol Res
; 3(11): 1248-56, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26130065
10.
Safety, tolerability and immunogenicity of GS-4774, a hepatitis B virus-specific therapeutic vaccine, in healthy subjects: a randomized study.
Vaccine
; 32(39): 4925-31, 2014 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25045824
11.
A whole recombinant yeast-based therapeutic vaccine elicits HBV X, S and Core specific T cells in mice and activates human T cells recognizing epitopes linked to viral clearance.
PLoS One
; 9(7): e101904, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25051027
12.
Whole recombinant yeast-based immunotherapy induces potent T cell responses targeting HCV NS3 and Core proteins.
Vaccine
; 25(8): 1452-63, 2007 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17098335
13.
A randomized, placebo-controlled trial of oral beclomethasone dipropionate as a prednisone-sparing therapy for gastrointestinal graft-versus-host disease.
Blood
; 109(10): 4557-63, 2007 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17244684
14.
Yeasts encoding tumour antigens in cancer immunotherapy.
Expert Opin Biol Ther
; 5(4): 565-75, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15934834