Detalhe da pesquisa
1.
Distinctive In Vitro Phenotypes in iPSC-Derived Neurons From Patients With Gain- and Loss-of-Function SCN2A Developmental and Epileptic Encephalopathy.
J Neurosci
; 44(8)2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38148154
2.
Generation of a stably transfected mouse embryonic stem cell line for inducible differentiation to excitatory neurons.
Exp Cell Res
; 435(1): 113902, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38145818
3.
Carbogen-Induced Respiratory Acidosis Blocks Experimental Seizures by a Direct and Specific Inhibition of NaV1.2 Channels in the Axon Initial Segment of Pyramidal Neurons.
J Neurosci
; 43(10): 1658-1667, 2023 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36732074
4.
Therapeutic Inhibition of Acid-Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury.
Circulation
; 144(12): 947-960, 2021 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34264749
5.
CDKL5 deficiency disorder: molecular insights and mechanisms of pathogenicity to fast-track therapeutic development.
Biochem Soc Trans
; 50(4): 1207-1224, 2022 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35997111
6.
Can mutation-mediated effects occurring early in development cause long-term seizure susceptibility in genetic generalized epilepsies?
Epilepsia
; 59(5): 915-922, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29658992
7.
Multipotent caudal neural progenitors derived from human pluripotent stem cells that give rise to lineages of the central and peripheral nervous system.
Stem Cells
; 33(6): 1759-70, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25753817
8.
An integrated in vitro human iPSCs-derived neuron and in vivo animal approach for preclinical screening of anti-seizure compounds.
J Adv Res
; 2023 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37995945
9.
The role of the adenosine system in epilepsy and its comorbidities.
Br J Pharmacol
; 2023 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37076128
10.
Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects.
Nat Commun
; 14(1): 3403, 2023 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37296101
11.
Targeting the AAVS1 Site by CRISPR/Cas9 with an Inducible Transgene Cassette for the Neuronal Differentiation of Human Pluripotent Stem Cells.
Methods Mol Biol
; 2495: 99-114, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35696030
12.
Early and progressive dysfunction revealed by in vivo neurite imaging in the rNLS8 TDP-43 mouse model of ALS.
Neuroimage Clin
; 34: 103016, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35483133
13.
Impaired glymphatic function in the early stages of disease in a TDP-43 mouse model of amyotrophic lateral sclerosis.
Transl Neurodegener
; 11(1): 17, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35287738
14.
In vitro neurons learn and exhibit sentience when embodied in a simulated game-world.
Neuron
; 110(23): 3952-3969.e8, 2022 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36228614
15.
Antisense oligonucleotide therapy for KCNT1 encephalopathy.
JCI Insight
; 7(23)2022 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36173683
16.
Antisense oligonucleotide therapy reduces seizures and extends life span in an SCN2A gain-of-function epilepsy model.
J Clin Invest
; 131(23)2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34850743
17.
Scientific communication and the semantics of sentience.
Neuron
; 111(5): 606-607, 2023 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36863320
18.
Author Correction: Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects.
Nat Commun
; 14(1): 3566, 2023 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37322043
19.
New era of personalised epilepsy management.
BMJ
; 371: m3658, 2020 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33037001
20.
Non-linear elasticity of core/shell spun PGS/PLLA fibres and their effect on cell proliferation.
Biomaterials
; 34(27): 6306-17, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23747009