Detalhe da pesquisa
1.
Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold.
J Enzyme Inhib Med Chem
; 38(1): 2270180, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37850364
2.
Synergistic Effects of A Combined Treatment of Glioblastoma U251 Cells with An Anti-miR-10b-5p Molecule and An AntiCancer Agent Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole Scaffold.
Int J Mol Sci
; 23(11)2022 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35682670
3.
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
Bioorg Chem
; 112: 104919, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33957538
4.
Apoptosis Pathways Triggered by a Potent Antiproliferative Hybrid Chalcone on Human Melanoma Cells.
Int J Mol Sci
; 22(24)2021 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34948260
5.
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
Bioorg Chem
; 97: 103665, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32086053
6.
Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold.
Molecules
; 25(7)2020 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32272719
7.
Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents.
Molecules
; 25(9)2020 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32384805
8.
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy.
Med Res Rev
; 38(4): 1031-1072, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28682469
9.
3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
Bioorg Chem
; 80: 361-374, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29986184
10.
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
J Enzyme Inhib Med Chem
; 33(1): 1225-1238, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30141353
11.
Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells.
J Enzyme Inhib Med Chem
; 33(1): 727-742, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29620429
12.
Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives.
Bioorg Med Chem Lett
; 24(18): 4568-4574, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25131537
13.
Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5-substituted thiophene derivatives as allosteric enhancers of the A1 adenosine receptor.
Bioorg Med Chem
; 22(1): 148-66, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24332652
14.
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.
Bioorg Med Chem
; 22(18): 5097-109, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24398384
15.
TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis.
Angiogenesis
; 16(3): 647-62, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23456551
16.
The new iodoacetamidobenzofuran derivative TR120 decreases STAT5 expression and induces antitumor effects in imatinib-sensitive and imatinib-resistant BCR-ABL-expressing leukemia cells.
Anticancer Drugs
; 24(4): 384-93, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23370613
17.
Allosteric modulation of A1-adenosine receptor: a review.
Drug Discov Today Technol
; 10(2): e285-96, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24050280
18.
Design, synthesis and biological evaluation of novel 2,4-thiazolidinedione derivatives able to target the human BAG3 protein.
Eur J Med Chem
; 261: 115824, 2023 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783101
19.
Development of a clot-adhesive coating to improve the performance of thrombectomy devices.
J Neurointerv Surg
; 15(12): 1207-1211, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36878688
20.
Pyrrolo- and pyrazolo-[3,4-e][1,2,4]triazolo[1,5-c]pyrimidines as adenosine receptor antagonists.
Bioorg Med Chem
; 20(2): 1046-59, 2012 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22204739