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1.
BMC Infect Dis ; 20(1): 70, 2020 Jan 22.
Artigo em Inglês | MEDLINE | ID: mdl-31969122

RESUMO

After publication of the original article [1], we have noticed that the word 'Carbapenem-producing' should be replaced with 'Carbapenemase-producing'.

2.
Euro Surveill ; 25(15)2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-32317052

RESUMO

On 20 November 2019, Lassa fever was diagnosed in a physician repatriated from Sierra Leone to the Netherlands. A second physician with suspected Lassa fever, repatriated a few days later from the same healthcare facility, was confirmed infected with Lassa virus on 21 November. Comprehensive contact monitoring involving high- and low-risk contacts proved to be feasible and follow-up of the contacts did not reveal any case of secondary transmission in the Netherlands.


Assuntos
Busca de Comunicante , Pessoal de Saúde , Febre Lassa/diagnóstico , Vírus Lassa/isolamento & purificação , Antivirais/uso terapêutico , Infecção Hospitalar , Feminino , Humanos , Transmissão de Doença Infecciosa do Paciente para o Profissional , Febre Lassa/tratamento farmacológico , Vírus Lassa/genética , Masculino , Países Baixos , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Serra Leoa , Viagem , Sequenciamento Completo do Genoma
3.
BMC Infect Dis ; 19(1): 1050, 2019 Dec 11.
Artigo em Inglês | MEDLINE | ID: mdl-31829149

RESUMO

BACKGROUND: Antimicrobial resistance (AMR) increasingly threatens public health. Carbapenem-producing gram-negative bacteria (CPB) pose the biggest threat. The risk for CPB spread is heightened during the transfer of a CPB-positive patient between different healthcare institutions or healthcare providers. We aimed to gain insight into the frequency of CPB-positive patients in the Dutch provinces of Noord-Holland (NH) and Flevoland (FL). Secondly, we aimed to obtain a deeper understanding of the communication between healthcare providers during transfers of CPB-positive patients and explore possible communication-related risk situations for CPB spread. METHODS: This mixed-methods study consisted of a quantitative and qualitative section. For the quantitative section, 14 laboratories that provide diagnostics in NH and FL voluntarily reported carbapenem-producing Enterobacteriaceae (CPE) positive patients between February 2018 and February 2019. Additionally, two laboratories reported carbapenem-resistant Acinetobacter spp. (CRA) and carbapenem-resistant Pseudomonas aeruginosa (CRP) positive patients. For the qualitative section, healthcare providers of reported patients were interviewed about information exchange during patient transfers, precautionary measures and knowledge and beliefs concerning CPB. RESULTS: In total, 50 CPE-positive, 10 CRA-positive and 4 CRP-positive patients were reported during the inclusion period. Eighteen index-specific and 2 general interviews were conducted with 20 different care providers of 9 patients. The interviews revealed that, in most cases, information concerning the patient was transferred timely, but often a standardized method for sharing the information within and between institutions was lacking. Factors that enhanced care providers' motivation to adhere to precautionary measures were taking responsibility for the health of other patients, (pregnant) colleagues and for ones own health. Factors that reduced motivation were not acknowledging the relevance of the precautionary measures, a perceived negative impact of the measures on patients' recovery, differences in precautionary measures between healthcare settings and incomprehension for changes in precautionary measures. CONCLUSIONS: CPB-positivity occurred more frequently than expected in the Dutch provinces of NH and FL. Standardizing the transference of information concerning CPB-positive patients, implementing transmural agreements, training personnel on CPB knowledge and procedures, launching a national website on CPB and assigning one or several designated employees for CPB within healthcare institutions could improve communication between healthcare providers and thereby decrease the risk of CPB transmission.


Assuntos
Antibacterianos/farmacologia , Carbapenêmicos/farmacologia , Transmissão de Doença Infecciosa/prevenção & controle , Farmacorresistência Bacteriana , Bactérias Gram-Negativas/fisiologia , Pessoal de Saúde , Transferência de Pacientes , Idoso , Antibacterianos/efeitos adversos , Carbapenêmicos/efeitos adversos , Testes Diagnósticos de Rotina , Feminino , Bactérias Gram-Negativas/efeitos dos fármacos , Humanos , Masculino , Pessoa de Meia-Idade , Países Baixos , Risco
4.
Foodborne Pathog Dis ; 9(2): 102-7, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22047057

RESUMO

Between April and May 2010, several medical microbiological laboratories in the Netherlands notified a total of 90 cases of Salmonella enterica serovar Typhimurium with the same antibiogram type (resistant for ampicillin, tetracycline, and co-trimoxazol) and the same multiple locus variable number tandem repeats analysis pattern (03-16-09-NA-311) or single locus variants. Date of illness onset ranged from end of March to mid-May with a peak in the second week of April. Almost half of the cases were hospitalized. Cases completed a questionnaire about food items and other risk factors in the 7 days before illness onset. A matched case-control study was performed. Consumption of "ossenworst" (matched odds ratio 48.2 [95% confidence interval (CI): 3.9-595.9]) and filet américain (8.5 [95% CI: 1.0-73.6]) were found to be significant risk factors for illness. Eighty percent of the cases had eaten at least one or both raw meat products. The producer of the ground beef that was used to produce the "ossenworst" was identified, but no microbiological evidence was found. Consumers should be made more aware of the presence of raw meat in ready-to-eat products and of the potential risk in eating these products. Vulnerable persons such as young children, elderly, and persons with poor health should be discouraged from eating these products. Detection of this outbreak was mainly based on the antibiogram pattern that had identified possible cases 10 days before detailed typing results from the reference laboratory became available, thus facilitating early case findings.


Assuntos
Surtos de Doenças/estatística & dados numéricos , Produtos da Carne/microbiologia , Intoxicação Alimentar por Salmonella/epidemiologia , Salmonella typhimurium/isolamento & purificação , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Animais , Estudos de Casos e Controles , Bovinos , Criança , Pré-Escolar , Farmacorresistência Bacteriana Múltipla , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Países Baixos/epidemiologia , Intoxicação Alimentar por Salmonella/microbiologia , Salmonella typhimurium/efeitos dos fármacos , Salmonella typhimurium/genética , Inquéritos e Questionários , Adulto Jovem
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