Detalhe da pesquisa
1.
Capivasertib combines with docetaxel to enhance anti-tumour activity through inhibition of AKT-mediated survival mechanisms in prostate cancer.
Br J Cancer
; 130(8): 1377-1387, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38396173
2.
Characterization of full-length p53 aggregates and their kinetics of formation.
Biophys J
; 121(22): 4280-4298, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36230002
3.
Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival.
J Pathol
; 237(2): 152-65, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25965974
4.
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation.
Sci Signal
; 17(825): eadf2670, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38412255
5.
The role of branched-chain aminotransferase 1 in driving glioblastoma cell proliferation and invasion varies with tumor subtype.
Neurooncol Adv
; 5(1): vdad120, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37885806
6.
Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models.
NPJ Breast Cancer
; 9(1): 64, 2023 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37543694
7.
The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER+ Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance.
Cancer Res
; 83(23): 3989-4004, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37725704
8.
Hepatic overexpression of a constitutively active form of liver glycogen synthase improves glucose homeostasis.
J Biol Chem
; 285(48): 37170-7, 2010 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20841354
9.
Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy.
Nat Neurosci
; 10(11): 1407-13, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17952067
10.
Metabolic imaging with hyperpolarized [1-13C] pyruvate in patient-derived preclinical mouse models of breast cancer.
STAR Protoc
; 2(3): 100608, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34189473
11.
Regulation of glycogen synthesis by the laforin-malin complex is modulated by the AMP-activated protein kinase pathway.
Hum Mol Genet
; 17(5): 667-78, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18029386
12.
18F-C2Am: a targeted imaging agent for detecting tumor cell death in vivo using positron emission tomography.
EJNMMI Res
; 10(1): 151, 2020 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33296043
13.
Breast cancer-associated macrophages promote tumorigenesis by suppressing succinate dehydrogenase in tumor cells.
Sci Signal
; 13(652)2020 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33023985
14.
Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer.
Cancer Cell
; 38(4): 516-533.e9, 2020 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32976773
15.
Magnetic Resonance Imaging Is More Sensitive Than PET for Detecting Treatment-Induced Cell Death-Dependent Changes in Glycolysis.
Cancer Res
; 79(14): 3557-3569, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31088837
16.
Metastatic small cell carcinoma to the thyroid gland: a pathologic and molecular study demonstrating the origin in the urinary bladder.
Endocr Pathol
; 19(3): 190-6, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18446450
17.
Metabolic Imaging Detects Low Levels of Glycolytic Activity That Vary with Levels of c-Myc Expression in Patient-Derived Xenograft Models of Glioblastoma.
Cancer Res
; 78(18): 5408-5418, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30054337
18.
Author Correction: Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models.
NPJ Breast Cancer
; 9(1): 76, 2023 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37726304
19.
Author Correction: Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models.
NPJ Breast Cancer
; 9(1): 69, 2023 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37596288
20.
Enhanced detection of circulating tumor DNA by fragment size analysis.
Sci Transl Med
; 10(466)2018 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30404863