Detalhe da pesquisa
1.
RNA Toxicity and Perturbation of rRNA Processing in Spinocerebellar Ataxia Type 2.
Mov Disord
; 36(11): 2519-2529, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34390268
2.
ATXN2-AS, a gene antisense to ATXN2, is associated with spinocerebellar ataxia type 2 and amyotrophic lateral sclerosis.
Ann Neurol
; 80(4): 600-15, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27531668
3.
Quantitative Proteomic Analysis Reveals Similarities between Huntington's Disease (HD) and Huntington's Disease-Like 2 (HDL2) Human Brains.
J Proteome Res
; 15(9): 3266-83, 2016 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27486686
4.
Phosphorodiamidate morpholino oligomers suppress mutant huntingtin expression and attenuate neurotoxicity.
Hum Mol Genet
; 23(23): 6302-17, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25035419
5.
Pathogenic insights from Huntington's disease-like 2 and other Huntington's disease genocopies.
Curr Opin Neurol
; 29(6): 743-748, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27749395
6.
Neuropathology and Cellular Pathogenesis of Spinocerebellar Ataxia Type 12.
Mov Disord
; 30(13): 1813-1824, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26340331
7.
A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression.
Hum Mol Genet
; 20(17): 3467-77, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21672921
8.
Loss of junctophilin-3 contributes to Huntington disease-like 2 pathogenesis.
Ann Neurol
; 71(2): 245-57, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22367996
9.
Brain, blood, and iron: perspectives on the roles of erythrocytes and iron in neurodegeneration.
Neurobiol Dis
; 46(3): 607-24, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22426390
10.
A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity.
Sci Rep
; 11(1): 6157, 2021 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33731741
11.
Diced triplets expose neurons to RISC.
PLoS Genet
; 8(2): e1002545, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22383898
12.
Exploring Novel Biologically-Relevant Chemical Space Through Artificial Intelligence: The NCATS ASPIRE Program.
Front Robot AI
; 6: 143, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-33501158
13.
A comparison of huntington disease and huntington disease-like 2 neuropathology.
J Neuropathol Exp Neurol
; 67(4): 366-74, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18379432
14.
Absence of Acanthocytosis in Huntington's Disease-like 2: A Prospective Comparison with Huntington's Disease.
Tremor Other Hyperkinet Mov (N Y)
; 7: 512, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29226019
15.
Eighth International Chorea-Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points.
Tremor Other Hyperkinet Mov (N Y)
; 7: 428, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28224046
16.
Assessing a peptidylic inhibitor-based therapeutic approach that simultaneously suppresses polyglutamine RNA- and protein-mediated toxicities in patient cells and Drosophila.
Dis Model Mech
; 9(3): 321-34, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26839389
17.
Huntington's disease like-2: review and update.
Acta Neurol Taiwan
; 14(1): 1-8, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15835282
18.
Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65.
Sci Rep
; 5: 12521, 2015 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26218986
19.
Repeat expansion and autosomal dominant neurodegenerative disorders: consensus and controversy.
Expert Rev Mol Med
; 5(21): 1-24, 2003 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-14585172
20.
Mapping biologically active chemical space to accelerate drug discovery.
Nat Rev Drug Discov
; 18(2): 83-84, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30710133