Detalhe da pesquisa
1.
Pharmacologic Comparison of Clinical Neutral Endopeptidase Inhibitors in a Rat Model of Acute Secretory Diarrhea.
J Pharmacol Exp Ther
; 357(2): 423-31, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26907621
2.
Evaluation of spiropiperidine hydantoins as a novel class of antimalarial agents.
Bioorg Med Chem
; 23(16): 5144-50, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25797165
3.
Synthesis of new verapamil analogues and their evaluation in combination with rifampicin against Mycobacterium tuberculosis and molecular docking studies in the binding site of efflux protein Rv1258c.
Bioorg Med Chem Lett
; 24(14): 2985-90, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24894561
4.
A simplified, G-CSF-free procedure allows for in vivo HSC gene therapy of sickle cell disease in a mouse model.
Blood Adv
; 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38843380
5.
Antibody-drug conjugates plus Janus kinase inhibitors enable MHC-mismatched allogeneic hematopoietic stem cell transplantation.
J Clin Invest
; 131(24)2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34730109
6.
Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.
Bioorg Med Chem Lett
; 20(2): 576-80, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20005097
7.
Targeting CXCR4, VLA-4, and CXCR2 for hematopoietic stem cell mobilization.
Blood Adv
; 8(6): 1379-1383, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38190608
8.
Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells.
J Clin Invest
; 129(7): 2745-2759, 2019 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085833
9.
Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in Mice.
Cell Mol Gastroenterol Hepatol
; 2(4): 499-518, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28174730
10.
Discovery of N-(4-Fluoro-3-methoxybenzyl)-6-(2-(((2S,5R)-5-(hydroxymethyl)-1,4-dioxan-2-yl)methyl)-2H-tetrazol-5-yl)-2-methylpyrimidine-4-carboxamide. A Highly Selective and Orally Bioavailable Matrix Metalloproteinase-13 Inhibitor for the Potential Treatment of Osteoarthritis.
J Med Chem
; 59(1): 313-27, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26653735
11.
Anti-metastatic properties of RGD-peptidomimetic agents S137 and S247.
Clin Exp Metastasis
; 21(2): 129-38, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15168730
12.
Adenovirus inhibition by peptidomimetic integrin antagonists.
Antiviral Res
; 55(1): 169-78, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12076761
13.
Evaluation of aminohydantoins as a novel class of antimalarial agents.
ACS Med Chem Lett
; 5(1): 89-93, 2014 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900778
14.
Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.
Nat Med
; 19(12): 1617-24, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24216753
15.
R-isomers of Arg-Gly-Asp (RGD) mimics as potent alphavbeta3 inhibitors.
Bioorg Med Chem
; 15(11): 3783-800, 2007 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17399986
16.
From bench to clinic: bridging the translational gap in neglected disease drug development.
Future Med Chem
; 3(10): 1253-7, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21859300