Detalhe da pesquisa
1.
Long-term safety and efficacy outcomes of valoctocogene roxaparvovec gene transfer up to 6 years post-treatment.
Haemophilia
; 30(2): 320-330, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38317480
2.
Multiyear Follow-up of AAV5-hFVIII-SQ Gene Therapy for Hemophilia A.
N Engl J Med
; 382(1): 29-40, 2020 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31893514
3.
Short-term transcriptional response to IL-17 receptor-A antagonism in the treatment of psoriasis.
J Allergy Clin Immunol
; 145(3): 922-932, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31883845
4.
Effect of IL-17 receptor A blockade with brodalumab in inflammatory diseases.
Rheumatology (Oxford)
; 55(suppl 2): ii43-ii55, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27856660
5.
The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses.
Trends Immunol
; 34(4): 174-81, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23291100
6.
Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti-IL-17 receptor monoclonal antibody.
J Immunol
; 192(8): 3828-36, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24646743
7.
Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis.
N Engl J Med
; 366(13): 1181-9, 2012 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22455412
8.
Cellular responses to individual amino-acid depletion in antibody-expressing and parental CHO cell lines.
Biotechnol Bioeng
; 111(5): 965-79, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24254056
9.
Large-scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes.
J Allergy Clin Immunol
; 139(3): 1061-1064.e4, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27871878
10.
Interindividual variability in transgene mRNA and protein production following adeno-associated virus gene therapy for hemophilia A.
Nat Med
; 28(4): 789-797, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35411075
11.
Molecular analysis of AAV5-hFVIII-SQ vector-genome-processing kinetics in transduced mouse and nonhuman primate livers.
Mol Ther Methods Clin Dev
; 24: 142-153, 2022 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35036471
12.
Evidence for endotoxin contamination in plastic Na+-heparin blood collection tube lots.
Clin Chem
; 56(9): 1483-91, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20663962
13.
Neurofilament light is a treatment-responsive biomarker in CLN2 disease.
Ann Clin Transl Neurol
; 6(12): 2437-2447, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31814335
14.
Distinguishing Molecular Features of Allergic Fungal Rhinosinusitis.
Otolaryngol Head Neck Surg
; 159(1): 185-193, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29584543
15.
Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-γ Antibody, in Patients With Discoid Lupus Erythematosus.
Arthritis Rheumatol
; 69(5): 1028-1034, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28118537
16.
The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings.
J Invest Dermatol
; 133(1): 17-26, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22673731
17.
A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis.
Arthritis Res Ther
; 15(5): R164, 2013 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24286136
18.
Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial.
J Invest Dermatol
; 132(10): 2466-2469, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22622425